7-bromo-2,4,8,9-tetrazabicyclo[4.3.0]nona-2,4,6,9-tetraen-5-amine

Product Name: 7-bromo-2,4,8,9-tetrazabicyclo[4.3.0]nona-2,4,6,9-tetraen-5-amine
CAS No.: 83255-86-1
Chemical Name: 7-bromo-2,4,8,9-tetrazabicyclo[4.3.0]nona-2,4,6,9-tetraen-5-amine
Synonyms: 9-tetraen-5-amine;9-tetrazabicyclo[4.3.0]nona-2;4-Amino-3-Bromo-pyrazolo[3,4-d]pyrimidine;3-BROMO-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE;3-bromo-2H-pyrazolo[4,3-e]pyrimidin-4-amine;3-bromo-2H-pyrazolo[3,4-d]pyrimidin-4-amine;4-amine, 3-bromo-1H-Pyrazolo[3,4-d]pyrimidin;4-Amino-3-bromo-1H-pyrazolo[3,4-d]pyrimidine;4-Amino-3-bromo-1H-pyrazole(3,4-d)pyrimidine;3-Bromo-1H-pyrazolo[3,4-d]pyrimidinyl-4-amine
CBNumber: CB71459422
Molecular Formula: C5H4BrN5
Formula Weight: 214.02
MOL File: 83255-86-1.mol

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7-bromo-2,4,8,9-tetrazabicyclo[4.3.0]nona-2,4,6,9-tetraen-5-amine Property

Melting point:: 350°C(lit.)
Boiling point:: 287.4±50.0 °C(Predicted)
Density: 2.54±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
form: powder to crystal
pka: 10.32±0.20(Predicted)
color: White to Light yellow
InChI: InChI=1S/C5H4BrN5/c6-3-2-4(7)8-1-9-5(2)11-10-3/h1H,(H3,7,8,9,10,11)
InChIKey: GZQVGSRUUTUJNG-UHFFFAOYSA-N
SMILES: C1=NC(N)=C2C(Br)=NNC2=N1

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Safety

Hazard Codes: Xn
Risk Statements: 22
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: ADE001441
Product name: 3-Bromo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Purity: Aldrich
Packaging: 1g
Price: $497
Updated: 2025/07/31

TCI Chemical

Product number: B4630
Product name: 3-Bromo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Purity: >97.0%(HPLC)(N)
Packaging: 1g
Price: $33
Updated: 2025/07/31

TCI Chemical

Product number: B4630
Product name: 3-Bromo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Purity: >97.0%(HPLC)(N)
Packaging: 5g
Price: $164
Updated: 2024/03/01

TRC

Product number: B997215
Product name: 3-Bromo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Packaging: 100mg
Price: $75
Updated: 2021/12/16

ChemScene

Product number: CS-W008671
Product name: 3-Bromo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Purity: 99.45%
Packaging: 5g
Price: $19
Updated: 2021/12/16

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7-bromo-2,4,8,9-tetrazabicyclo[4.3.0]nona-2,4,6,9-tetraen-5-amine Chemical Properties,Usage,Production

Chemical Properties

Yellow solid

Synthesis

2380-63-4

83255-86-1

The general procedure for the synthesis of 3-bromo-1H-pyrazolo[3,4-d]pyrimidin-4-amine using 4-aminopyrazolo[3,4-d]pyrimidine as starting material was as follows: 1H-pyrazolo[3,4-d]pyrimidin-4-amine (20.0 g, 148.0 mmol) and N-bromosuccinimide (27.7 g, 155.4 mmol) were suspended in N,N- dimethylformamide (DMF, 400 mL). The reaction mixture was heated to 80 °C and the reaction was stirred at this temperature for 2.5 hours. Upon completion of the reaction, the mixture was cooled to room temperature, followed by slow dropwise addition of water (800 mL) to quench the reaction. The resulting precipitate was collected by filtration and suspended in saturated sodium sulfite solution (100 mL). The solid product was filtered again and washed sequentially with water (3 x 100 mL) and cold ethanol (2 x 50 mL). Finally, the product was dried under vacuum to afford 3-bromo-1H-pyrazolo[3,4-d]pyrimidin-4-amine as a beige solid (22.7 g, 105.9 mmol, 72% yield).

References

[1] Patent: WO2017/17619, 2017, A1. Location in patent: Page/Page column 8-9
[2] Bioorganic and Medicinal Chemistry, 2018, vol. 26, # 17, p. 4774 - 4786
[3] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1982, vol. 18, # 7, p. 753 - 755
[4] Khimiya Geterotsiklicheskikh Soedinenii, 1982, # 7, p. 982 - 984
[5] Patent: EP2548877, 2013, A1. Location in patent: Paragraph 0416

7-bromo-2,4,8,9-tetrazabicyclo[4.3.0]nona-2,4,6,9-tetraen-5-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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7-bromo-2,4,8,9-tetrazabicyclo[4.3.0]nona-2,4,6,9-tetraen-5-amine Suppliers

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View Lastest Price from 7-bromo-2,4,8,9-tetrazabicyclo[4.3.0]nona-2,4,6,9-tetraen-5-amine manufacturers

Shaanxi Xianhe Biotech Co., Ltd

Product: 3-Bromo-1H-pyrazolo[3,4-d]pyrimidin-4-amine 83255-86-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 1000kg
Release date: 2025-04-17

Nanjing Fred Technology Co., Ltd

Product: 3-Bromo-1H-pyrazolo[3,4-d]pyrimidin-4-amine 83255-86-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1 ton
Release date: 2023-12-28

Henan Fengda Chemical Co., Ltd

Product: 7-bromo-2,4,8,9-tetrazabicyclo[4.3.0]nona-2,4,6,9-tetraen-5-amine 83255-86-1
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-09

83255-86-1, 7-bromo-2,4,8,9-tetrazabicyclo[4.3.0]nona-2,4,6,9-tetraen-5-amineRelated Search:

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83255-86-1