2-Iodo-6-methylpyridine
- Product Name
- 2-Iodo-6-methylpyridine
- CAS No.
- 62674-71-9
- Chemical Name
- 2-Iodo-6-methylpyridine
- Synonyms
- 6-Iodo-2-picoline;2-Iodo-6-methylpyridine;Pyridine,2-iodo-6-methyl-;2,2'-Biquinoline-4,4'-diyl bis(sulfide);2-Iodo-6-methylpyridine ISO 9001：2015 REACH
- CBNumber
- CB71471149
- Molecular Formula
- C6H6IN
- Formula Weight
- 219.02
- MOL File
- 62674-71-9.mol
2-Iodo-6-methylpyridine Property
- Boiling point:
- 222.1±20.0 °C(Predicted)
- Density
- 1.810±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 2.57±0.10(Predicted)
- Appearance
- Colorless to light yellow Liquid
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- I737678
- Product name
- 2-Iodo-6-methylpyridine
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- I737678
- Product name
- 2-Iodo-6-methylpyridine
- Packaging
- 100mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- 9463AB
- Product name
- 6-Iodo-2-picoline
- Packaging
- 250mg
- Price
- $131
- Updated
- 2021/12/16
- Product number
- 3H32-H-67
- Product name
- 2-Iodo-6-methylpyridine
- Packaging
- 1g
- Price
- $432
- Updated
- 2021/12/16
- Product number
- 9463AB
- Product name
- 6-Iodo-2-picoline
- Packaging
- 1g
- Price
- $251
- Updated
- 2021/12/16
2-Iodo-6-methylpyridine Chemical Properties,Usage,Production
Synthesis
5315-25-3
75-36-5
62674-71-9
General procedure for the synthesis of 2-iodo-6-methylpyridine from 2-bromo-6-methylpyridine and acetyl chloride: to an anhydrous acetonitrile (13 mL) solution of 2-bromo-6-methylpyridine (2.0 g, 11.6 mmol) and sodium iodide (2.78 g, 18.6 mmol) was slowly added acetyl chloride (1.9 g, 24.4 mmol) dropwise, and the reaction mixture formed a light-yellow The reaction mixture formed a pale yellow suspension. The suspension was heated to reflux. After 16 hours of reaction, the conversion was shown to be 50% by gas chromatography (GC) analysis. Subsequently, acetyl chloride (1 eq.) and sodium iodide (0.8 eq.) were added additionally and refluxing was continued for 16 h. GC analysis showed 90% conversion with the presence of bromine and chlorine by-products detected. Upon completion of the reaction, the mixture was cooled to room temperature, diluted with 10% aqueous potassium carbonate and 5% aqueous sodium bisulfite (75 mL each), and extracted with ether (2 x 75 mL). The organic phases were combined, washed with potassium carbonate/sodium bisulfite solution, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford 2.39 g (94%) of the crude product 2-iodo-6-methylpyridine as a dark oil, which was directly used in the subsequent reaction without further purification. The structure of the product was confirmed by 1H NMR (CDCl3): δ 2.52 (s, 3H), 7.10 (d, 1H, J = 7.51 Hz), 7.20 (t, 1H, J = 7.69 Hz), 7.58 (d, 1H, J = 7.69 Hz). Ref: Tetrahedron Lett. 1990, 31, 6757.
References
[1] Patent: US2002/19370, 2002, A1
2-Iodo-6-methylpyridine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Iodo-6-methylpyridine Suppliers
- Tel
- +49 5662 408730
- Fax
- +49 5662 4087320
- info@synchem.de
- Country
- Germany
- ProdList
- 4705
- Advantage
- 70
View Lastest Price from 2-Iodo-6-methylpyridine manufacturers
- Product
- 2-Iodo-6-methylpyridine 62674-71-9
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 20 tons
- Release date
- 2025-07-23
- Product
- 2-Iodo-6-methylpyridine 62674-71-9
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-31
- Product
- 2-Iodo-6-methylpyridine 62674-71-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11