(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol

Product Name: (2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol
CAS No.: 289893-25-0
Chemical Name: (2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol
Synonyms: Pefcalcitol;Amrioclomol;arimoclomol;BRX-220 free base;(2R-)Arimoclomol NEW;(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol;3-Pyridinecarboximidoyl chloride, N-[(2R)-2-hydroxy-3-(1-piperidinyl)propoxy]-, 1-oxide;aggregation,Heat shock proteins,HSP,co-inducer,system,BRX220,motor,Arimoclomol,inhibit,ubiquitin,BRX 220,neurons,misfolded,proteasome,BRX-220,protein,assemblies,clearance,Inhibitor
CBNumber: CB71480024
Molecular Formula: C14H20ClN3O3
Formula Weight: 313.78
MOL File: 289893-25-0.mol

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(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Property

Melting point:: 93 - 95o C
Boiling point:: 539.2±60.0 °C(Predicted)
Density: 1.32±0.1 g/cm3(Predicted)
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 14.03±0.20(Predicted)
color: White to Off-White
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H261In contact with water releases flammable gas

Precautionary statements

P223Keep away from any possible contact with water, because of violent reaction and possible flash fire.

P231+P232Handle under inert gas. Protect from moisture.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P335+P334Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.

P370+P378In case of fire: Use … for extinction.

P402+P404Store in a dry place. Store in a closed container.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: A771278
Product name: Arimoclomol
Packaging: 1mg
Price: $110
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA30834
Product name: (2R-)Arimoclomol NEW
Packaging: 5mg
Price: $175
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA30834
Product name: (2R-)Arimoclomol NEW
Packaging: 10mg
Price: $300
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA30834
Product name: (2R-)Arimoclomol NEW
Packaging: 25mg
Price: $475
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0007198
Product name: AMRIOCLOMOL
Purity: 95.00%
Packaging: 100MG
Price: $2732.5
Updated: 2021/12/16

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(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Chemical Properties,Usage,Production

Uses

Arimoclomol is a co-inducer of HSP that acts through heat shock factor 1 (HSF1) in cells undergoing cellular stress. Has therapeutic potential in motor neuron degenerative diseases. Potential treatment for liposomal storage disorders, such as Niemann-Pick disease type C.

(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Preparation Products And Raw materials

Raw materials

Preparation Products

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(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Suppliers

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289893-25-0, (2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-olRelated Search:

Aprepitant

(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol

arimoclomol

Amrioclomol

Pefcalcitol

(2R-)Arimoclomol NEW

BRX-220 free base

3-Pyridinecarboximidoyl chloride, N-[(2R)-2-hydroxy-3-(1-piperidinyl)propoxy]-, 1-oxide

aggregation,Heat shock proteins,HSP,co-inducer,system,BRX220,motor,Arimoclomol,inhibit,ubiquitin,BRX 220,neurons,misfolded,proteasome,BRX-220,protein,assemblies,clearance,Inhibitor

289893-25-0