ChemicalBook > CAS DataBase List > 1,3-DIBROMO-4-IODOBENZENE

1,3-DIBROMO-4-IODOBENZENE

Product Name
1,3-DIBROMO-4-IODOBENZENE
CAS No.
19393-94-3
Chemical Name
1,3-DIBROMO-4-IODOBENZENE
Synonyms
1,3-DIBROMO-4-IODOBENZENE;Benzene, 2,4-dibromo-1-iodo-;1,3-Dibromo-4-iodobenzene Solution;1,3-Dibromo-4-iodobenzene Solution in Isooctane
CBNumber
CB71500599
Molecular Formula
C6H3Br2I
Formula Weight
361.8
MOL File
19393-94-3.mol
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1,3-DIBROMO-4-IODOBENZENE Property

Melting point:
45-46℃
Boiling point:
299.1±20.0 °C(Predicted)
Density 
2.514±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform, Methanol (Slightly, Sonicated)
form 
solid
color 
White
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Safety

HS Code 
2903998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC
Product number
B426248
Product name
2,4-Dibromo-1-iodobenzene
Packaging
50mg
Price
$45
Updated
2021/12/16
TRC
Product number
B426248
Product name
2,4-Dibromo-1-iodobenzene
Packaging
500mg
Price
$85
Updated
2021/12/16
Matrix Scientific
Product number
095848
Product name
2,4-Dibromo-1-iodobenzene
Purity
95+%
Packaging
5g
Price
$123
Updated
2021/12/16
AK Scientific
Product number
J51078
Product name
2,4-Dibromo-1-iodobenzene
Packaging
5g
Price
$135
Updated
2021/12/16
Matrix Scientific
Product number
095848
Product name
2,4-Dibromo-1-iodobenzene
Purity
95+%
Packaging
1g
Price
$46
Updated
2021/12/16
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1,3-DIBROMO-4-IODOBENZENE Chemical Properties,Usage,Production

Synthesis

615-57-6

19393-94-3

The general procedure for the synthesis of 2,4-dibromoiodobenzene from 2,4-dibromoaniline is as follows:[Example of Manufacture 1]; Intermediate A1 of indeno compound A was produced by the following synthetic route.2,4-Dibromoaniline (10 g, 40 mmol) was suspended in an aqueous hydrochloric acid solution comprising 40 mL of concentrated hydrochloric acid and 30 mL of water, and the suspension was cooled at -8°C in an ice/salt bath. Aqueous sodium nitrite (3.0 g, 43 mmol, 1.1 eq./15 mL) was added dropwise over a period of 10 min, followed by stirring of the reaction mixture at -10 °C to 0 °C for 30 min to prepare the diazonium salt. The reaction solution was slowly added dropwise to an aqueous potassium iodide solution (60 g, 0.36 mmol, 9 eq/180 mL) over 20 min at room temperature. The reaction mixture was continued to be stirred at room temperature for 3 hours, after which dichloromethane (200 mL) and sodium bisulfite (2 g) were added to neutralize the free iodine. The organic layer was separated and washed sequentially with aqueous sodium bisulfite (100 mL) and saturated brine (30 mL) before drying with anhydrous magnesium sulfate. Subsequently, the solvent was removed by distillation to give a red liquid product. The product was purified by column chromatography (silica gel/hexane) to give a white solid (11.0 g, 76% yield).1H-NMR (400 MHz, CDCl3, TMS) data were as follows: δ 7.11 (1H, dd, J=8Hz, 2Hz), 7.69 (1H, d, J=8Hz), 7.76 (1H, d, J=2Hz).

References

[1] Organometallics, 2015, vol. 34, # 20, p. 4798 - 4801
[2] Angewandte Chemie - International Edition, 2008, vol. 47, # 5, p. 888 - 890
[3] Patent: EP2316816, 2011, A1. Location in patent: Page/Page column 14
[4] Journal of Organic Chemistry, 1987, vol. 52, # 5, p. 748 - 753
[5] Inorganic Chemistry, 2012, vol. 51, # 2, p. 799 - 811

1,3-DIBROMO-4-IODOBENZENE Preparation Products And Raw materials

Raw materials

Preparation Products

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1,3-DIBROMO-4-IODOBENZENE Suppliers

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View Lastest Price from 1,3-DIBROMO-4-IODOBENZENE manufacturers

Career Henan Chemical Co
Product
1,3-DIBROMO-4-IODOBENZENE 19393-94-3
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2018-08-22