4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine
- Product Name
- 4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine
- CAS No.
- 180869-36-7
- Chemical Name
- 4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine
- Synonyms
- 4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine;Pyrimidine,4-(dimethoxymethyl)-2-(methylthio)-;2-methylthiopyrimidine-4-carboxaldehyde dimethyl acetal;4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine ISO 9001：2015 REACH
- CBNumber
- CB71501455
- Molecular Formula
- C8H12N2O2S
- Formula Weight
- 200.26
- MOL File
- 180869-36-7.mol
4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine Property
- Boiling point:
- 273.0±25.0 °C(Predicted)
- Density
- 1.18±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 0.37±0.31(Predicted)
- Appearance
- light yellow liquid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D472543
- Product name
- 4-(Dimethoxymethyl)-2-(methylthio)pyrimidine
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 8H66-1-6D
- Product name
- 4-(Dimethoxymethyl)-2-(methylsulfanyl)pyrimidine
- Purity
- 97.0%
- Packaging
- 250mg
- Price
- $190
- Updated
- 2021/12/16
- Product number
- 126704
- Product name
- 4-(Dimethoxymethyl)-2-(methylthio)pyrimidine
- Purity
- >95%
- Packaging
- 1g
- Price
- $270
- Updated
- 2021/12/16
- Product number
- Z4313
- Product name
- 4-(Dimethoxymethyl)-2-(methylthio)pyrimidine
- Packaging
- 10g
- Price
- $371
- Updated
- 2021/12/16
- Product number
- 8H66-1-6D
- Product name
- 4-(Dimethoxymethyl)-2-(methylsulfanyl)pyrimidine
- Purity
- 97.0%
- Packaging
- 1g
- Price
- $540
- Updated
- 2021/12/16
4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine Chemical Properties,Usage,Production
Synthesis
6342-56-9
7732-18-5
4637-24-5
180869-36-7
General procedure: 2-methylthiopyrimidine-4-carbaldehyde dimethyl acetal (19.2 mL, 159.1 mmol) was mixed with N,N-dimethylformamide dimethyl acetal (21.12 mL, 159.1 mmol) in a 500 mL flask and the reaction was heated at 100 °C for 4.5 hours. After the reaction was completed, thiourea (11.0 g, 144.5 mmol), NaOMe (25 wt% MeOH solution, 39.7 mL, 173 mmol) and 30 mL of MeOH were added to the flask, and the reaction continued to be heated at 65°C for 18 hours. At the end of the reaction, the reaction solution was cooled to 25 °C and MeI (10.8 mL, 173 mmol) was added slowly over 5 min (note exothermic). After continuing the reaction for 3 h, the reaction solution was diluted with 250 mL of H2O and extracted with EtOAc (3 × 100 mL). The organic phases were combined, dried over Na2SO4 and concentrated to give 4-(dimethoxymethyl)-2-methylthiopyrimidine (26.8 g, 93% yield) as a brown oil.
References
[1] Patent: US5593991, 1997, A
[2] Patent: US5593992, 1997, A
[3] Patent: US5670527, 1997, A
[4] Patent: US5739143, 1998, A
[5] Patent: US5658903, 1997, A
4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine manufacturers
- Product
- 4-(Dimethoxymethyl)-2-(methylthio)pyrimidine 180869-36-7
- Price
- US $1.60-9.60/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-20
- Product
- 4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine 180869-36-7
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-15
- Product
- 4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine 180869-36-7
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-02-13