ChemicalBook > CAS DataBase List > 4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine

4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine

Product Name
4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine
CAS No.
180869-36-7
Chemical Name
4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine
Synonyms
4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine;Pyrimidine,4-(dimethoxymethyl)-2-(methylthio)-;2-methylthiopyrimidine-4-carboxaldehyde dimethyl acetal;4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine ISO 9001：2015 REACH
CBNumber
CB71501455
Molecular Formula
C8H12N2O2S
Formula Weight
200.26
MOL File
180869-36-7.mol
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4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine Property

Boiling point:
273.0±25.0 °C(Predicted)
Density 
1.18±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
0.37±0.31(Predicted)
Appearance
light yellow liquid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
D472543
Product name
4-(Dimethoxymethyl)-2-(methylthio)pyrimidine
Packaging
50mg
Price
$45
Updated
2021/12/16
SynQuest Laboratories
Product number
8H66-1-6D
Product name
4-(Dimethoxymethyl)-2-(methylsulfanyl)pyrimidine
Purity
97.0%
Packaging
250mg
Price
$190
Updated
2021/12/16
Matrix Scientific
Product number
126704
Product name
4-(Dimethoxymethyl)-2-(methylthio)pyrimidine
Purity
>95%
Packaging
1g
Price
$270
Updated
2021/12/16
AK Scientific
Product number
Z4313
Product name
4-(Dimethoxymethyl)-2-(methylthio)pyrimidine
Packaging
10g
Price
$371
Updated
2021/12/16
SynQuest Laboratories
Product number
8H66-1-6D
Product name
4-(Dimethoxymethyl)-2-(methylsulfanyl)pyrimidine
Purity
97.0%
Packaging
1g
Price
$540
Updated
2021/12/16
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4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine Chemical Properties,Usage,Production

Synthesis

6342-56-9

7732-18-5

4637-24-5

180869-36-7

General procedure: 2-methylthiopyrimidine-4-carbaldehyde dimethyl acetal (19.2 mL, 159.1 mmol) was mixed with N,N-dimethylformamide dimethyl acetal (21.12 mL, 159.1 mmol) in a 500 mL flask and the reaction was heated at 100 °C for 4.5 hours. After the reaction was completed, thiourea (11.0 g, 144.5 mmol), NaOMe (25 wt% MeOH solution, 39.7 mL, 173 mmol) and 30 mL of MeOH were added to the flask, and the reaction continued to be heated at 65°C for 18 hours. At the end of the reaction, the reaction solution was cooled to 25 °C and MeI (10.8 mL, 173 mmol) was added slowly over 5 min (note exothermic). After continuing the reaction for 3 h, the reaction solution was diluted with 250 mL of H2O and extracted with EtOAc (3 × 100 mL). The organic phases were combined, dried over Na2SO4 and concentrated to give 4-(dimethoxymethyl)-2-methylthiopyrimidine (26.8 g, 93% yield) as a brown oil.

References

[1] Patent: US5593991, 1997, A
[2] Patent: US5593992, 1997, A
[3] Patent: US5670527, 1997, A
[4] Patent: US5739143, 1998, A
[5] Patent: US5658903, 1997, A

4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
4-(Dimethoxymethyl)-2-(methylthio)pyrimidine 180869-36-7
Price
US $1.60-9.60/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-20
Dideu Industries Group Limited
Product
4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine 180869-36-7
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-15
Career Henan Chemical Co
Product
4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine 180869-36-7
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-02-13

180869-36-7, 4-(Dimethoxymethyl)-2-(methylthio)-pyrimidineRelated Search:

4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine 2-BENZYLSULFANYL-4-CHLORO-6-DIETHOXYMETHYL-PYRIMIDINE 4-DIMETHOXYMETHYL-2-PROPYLSULFANYL-PYRIMIDINE

  • 4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine
  • Pyrimidine,4-(dimethoxymethyl)-2-(methylthio)-
  • 2-methylthiopyrimidine-4-carboxaldehyde dimethyl acetal
  • 4-(Dimethoxymethyl)-2-(methylthio)-pyrimidine ISO 9001：2015 REACH
  • 180869-36-7
  • pharmacetical