ChemicalBook > CAS DataBase List > H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (Cys3-Cys9)

H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (Cys3-Cys9)

Product Name
H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (Cys3-Cys9)
CAS No.
309247-84-5
Chemical Name
H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (Cys3-Cys9)
Synonyms
CRUSTACEAN CARDIOACTIVE PEPTIDE, CCAP;Crustacean cardioactive peptide, free acid;Crustacean Cardioactive Peptide , CCAPfreeacid;H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (Cys3-Cys9);PRO-PHE-CYS-ASN-ALA-PHE-THR-GLY-CYS(DISULFIDE BRIDGE CYS3-CYS9);L-Cysteine, L-prolyl-L-phenylalanyl-L-cysteinyl-L-asparaginyl-L-alanyl-L-phenylalanyl-L-threonylglycyl-
CBNumber
CB71513078
Molecular Formula
C42H58N10O12S2
Formula Weight
959.1
MOL File
309247-84-5.mol
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H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (Cys3-Cys9) Property

storage temp. 
Store at -20°C
solubility 
DMSO : 50 mg/mL (52.13 mM);Water : < 0.1 mg/mL (insoluble)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (Cys3-Cys9) Chemical Properties,Usage,Production

Uses

Crustacean cardioactive peptide, free acid is a highly conserved, amidated cyclic nonapeptide, first isolated from the pericardial organs of the shore crab Carcinus maenas, where it has a role in regulating heartbeat; Crustacean cardioactive peptide, free acid also modulates the neuronal activity in other arthropods.

in vivo

CCAP, FMRFamide and SALDKNFMRFamide increase the mosquito antennal accessory pulsatile organ (APO) and heart contraction rates, increase hemolymph flow velocity in the antennal space[1].

References

[1] Suggs JM, et al. CCAP and FMRFamide-like peptides accelerate the contraction rate of the antennal accessory pulsatile organs (auxiliary hearts) of mosquitoes. J Exp Biol. 2016 Aug 1;219(Pt 15):2388-95. DOI:10.1242/jeb.141655
[2] Moris-Sanz M, et al. The study of the Bithorax-complex genes in patterning CCAP neurons reveals a temporal control of neuronal differentiation by Abd-B. Biol Open. 2015 Aug 14;4(9):1132-42. DOI:10.1242/bio.012872

H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (Cys3-Cys9) Preparation Products And Raw materials

Raw materials

Preparation Products

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309247-84-5, H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (Cys3-Cys9)Related Search:


  • CRUSTACEAN CARDIOACTIVE PEPTIDE, CCAP
  • H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (Cys3-Cys9)
  • PRO-PHE-CYS-ASN-ALA-PHE-THR-GLY-CYS(DISULFIDE BRIDGE CYS3-CYS9)
  • L-Cysteine, L-prolyl-L-phenylalanyl-L-cysteinyl-L-asparaginyl-L-alanyl-L-phenylalanyl-L-threonylglycyl-
  • Crustacean cardioactive peptide, free acid
  • Crustacean Cardioactive Peptide , CCAPfreeacid
  • 309247-84-5
  • C42H56N10O12S2
  • C42H58N10O12S2
  • Peptide