H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (Cys3-Cys9)
- Product Name
- H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (Cys3-Cys9)
- CAS No.
- 309247-84-5
- Chemical Name
- H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (Cys3-Cys9)
- Synonyms
- CRUSTACEAN CARDIOACTIVE PEPTIDE, CCAP;Crustacean cardioactive peptide, free acid;Crustacean Cardioactive Peptide , CCAPfreeacid;H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (Cys3-Cys9);PRO-PHE-CYS-ASN-ALA-PHE-THR-GLY-CYS(DISULFIDE BRIDGE CYS3-CYS9);L-Cysteine, L-prolyl-L-phenylalanyl-L-cysteinyl-L-asparaginyl-L-alanyl-L-phenylalanyl-L-threonylglycyl-
- CBNumber
- CB71513078
- Molecular Formula
- C42H58N10O12S2
- Formula Weight
- 959.1
- MOL File
- 309247-84-5.mol
H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (Cys3-Cys9) Property
- storage temp.
- Store at -20°C
- solubility
- DMSO : 50 mg/mL (52.13 mM);Water : < 0.1 mg/mL (insoluble)
- form
- Solid
- color
- White to off-white
H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (Cys3-Cys9) Chemical Properties,Usage,Production
Uses
Crustacean cardioactive peptide, free acid is a highly conserved, amidated cyclic nonapeptide, first isolated from the pericardial organs of the shore crab Carcinus maenas, where it has a role in regulating heartbeat; Crustacean cardioactive peptide, free acid also modulates the neuronal activity in other arthropods.
in vivo
CCAP, FMRFamide and SALDKNFMRFamide increase the mosquito antennal accessory pulsatile organ (APO) and heart contraction rates, increase hemolymph flow velocity in the antennal space[1].
References
[1] Suggs JM, et al. CCAP and FMRFamide-like peptides accelerate the contraction rate of the antennal accessory pulsatile organs (auxiliary hearts) of mosquitoes. J Exp Biol. 2016 Aug 1;219(Pt 15):2388-95. DOI:10.1242/jeb.141655
[2] Moris-Sanz M, et al. The study of the Bithorax-complex genes in patterning CCAP neurons reveals a temporal control of neuronal differentiation by Abd-B. Biol Open. 2015 Aug 14;4(9):1132-42. DOI:10.1242/bio.012872
H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (Cys3-Cys9) Preparation Products And Raw materials
Raw materials
Preparation Products
H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (Cys3-Cys9) Suppliers
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- Country
- Germany
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