derquantel
- Product Name
- derquantel
- CAS No.
- 187865-22-1
- Chemical Name
- derquantel
- Synonyms
- derquantel;Unii-0L0ugk6oox;2-Deoxoparaherquamide;2-DeoxoparaherquaMide, 2-DeoxoparaherquaMide A, 2-DesoxoparaherquaMide A, PF 00520904, PNU 141962;Spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,7'(8'H)-[5H,6H-5a,9a](iminomethano)[1H]cyclopent[f]indolizin]-10'-one, 2',3',8'a,9,9',10-hexahydro-1'-hydroxy-1',4,4,8',8',11'-hexamethyl-, (1'R,5'aS,7'R,8'aS,9'aR)-
- CBNumber
- CB71518503
- Molecular Formula
- C28H37N3O4
- Formula Weight
- 479.61
- MOL File
- 187865-22-1.mol
derquantel Property
- Boiling point:
- 641.3±55.0 °C(Predicted)
- Density
- 1.34
- storage temp.
- Store at -20°C
- solubility
- DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
- form
- A solid
- pka
- 15.18±0.60(Predicted)
- JECFA Number
- 75
N-Bromosuccinimide Price
- Product number
- 19441
- Product name
- Derquantel
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $321
- Updated
- 2024/03/01
- Product number
- 19441
- Product name
- Derquantel
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $1280
- Updated
- 2024/03/01
- Product number
- C4619
- Product name
- Derquantel
- Packaging
- 25mg
- Price
- $1381
- Updated
- 2021/12/16
- Product number
- C4619
- Product name
- Derquantel
- Packaging
- 5mg
- Price
- $345
- Updated
- 2021/12/16
- Product number
- 2982DC
- Product name
- Derquantel
- Packaging
- 5mg
- Price
- $436
- Updated
- 2021/12/16
derquantel Chemical Properties,Usage,Production
Description
Derquantel is an anthelmintic spiroindole that acts as a nicotinic acetylcholine receptor antagonist, causing flaccid paralysis and expulsion of nematodes. A combination of derquantel and the macrocyclic lactone, abamectin , has been found to have synergistic anthelmintic effects against gastrointestinal nematode parasites in sheep.
Uses
Derquantel is a semi-synthetic paraherquamide analogue prepared by removal of the 2-oxo group in a four-step sequence of N-protection, reduction, N-deprotection and a final reduction. Derquantel isa potent nematocide and was the first paraherquamide to be successfully commercialised in combination with avermectin. Derquantel, like other paraherquamides, induces a flaccid paralysis in nematodes thought to be due to inhibition of nicotinic acetylcholine receptors acting as an antagonist of acetylcholine.
Definition
ChEBI: Derquantel is an azaspiro compound.
derquantel Preparation Products And Raw materials
Raw materials
Preparation Products
derquantel Suppliers
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