ChemicalBook > CAS DataBase List > Tildipirosin

Tildipirosin

Product Name: Tildipirosin
CAS No.: 328898-40-4
Chemical Name: Tildipirosin
Synonyms: Zuprevo.;tildipirosin;Taijiluo Xin;Tildipirosin 98%;Tildipirosin USP/EP/BP;TILDIPIROSIN 328898-40-4;Tildipirosin in methanol;high qualtiy Tildipirosin;TIP; TILDIPIROSIN; ZUPREVO.;Tildipirosin, 10 mM in DMSO
CBNumber: CB71518543
Molecular Formula: C41H71N3O8
Formula Weight: 734.02
MOL File: 328898-40-4.mol

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Tildipirosin Property

Melting point:: >110°C (dec.)
Boiling point:: 846.8±65.0 °C(Predicted)
Density: 1.15
storage temp.: 2-8°C
solubility: Chloroform (Sparingly), DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 13.18±0.70(Predicted)
color: Off-White to Pale Beige
InChI: InChI=1/C41H71N3O8/c1-8-35-32(26-44-20-13-10-14-21-44)23-27(2)15-16-33(45)28(3)24-31(17-22-43-18-11-9-12-19-43)40(29(4)34(46)25-36(47)51-35)52-41-39(49)37(42(6)7)38(48)30(5)50-41/h15-16,23,28-32,34-35,37-41,46,48-49H,8-14,17-22,24-26H2,1-7H3/b16-15+,27-23+/t28-,29+,30-,31+,32-,34-,35-,37+,38-,39-,40-,41+/s3
InChIKey: HNDXPZPJZGTJLJ-IGVBWUSTNA-N
SMILES: [C@@H]1(O[C@H]2[C@@H](CCN3CCCCC3)C[C@@H](C)C(=O)C=CC(C)=C[C@H](CN3CCCCC3)[C@@H](CC)OC(=O)C[C@@H](O)[C@@H]2C)O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]1O |t:18,21,&1:0,2,3,13,22,30,37,39,42,44,46,50,r|

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H360May damage fertility or the unborn child

H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 17089
Product name: Tildipirosin
Purity: ≥95%
Packaging: 1mg
Price: $335
Updated: 2024/03/01

Cayman Chemical

Product number: 17089
Product name: Tildipirosin
Purity: ≥95%
Packaging: 5mg
Price: $1201
Updated: 2024/03/01

TRC

Product number: T440150
Product name: Tildipirosin
Packaging: 10mg
Price: $180
Updated: 2021/12/16

Usbiological

Product number: 021863
Product name: Tildipirosin
Packaging: 10mg
Price: $460
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FT137728
Product name: 20-Deoxo-23-deoxy-5-O-[3,6-dideoxy-3-(dimethylamino)-beta-D-glucopyranosyl]-20,23-di-1-piperidinyltylonolide
Packaging: 25mg
Price: $50
Updated: 2021/12/16

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Tildipirosin Chemical Properties,Usage,Production

Description

Tildiprosin is an antibiotic derived from a tylosin derivative by iodination and reaction with piperidine. Tildiprosin provides good protection against Bartonella henselae in livestock. Treatment of swine respiratory disease (SRD) associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Bordetella bronchiseptica and Haemophilus parasuis sensitive to tildipirosin. The introduction of a third basic moiety into the tylosin core provides a wider spectrum of antibiotic action than the dibasic analogues such as tilmicosin. Tildipirosin′s interaction with the ribosomal site of action differs from that of tylosin and tilmicosin.

Uses

Tildiprosin is a semi-synthetic antibiotic derived from a tylosin derivative by iodination and reaction with piperidine. The introduction of a third basic moiety into the tylosin core provides a wider spectrum of antibiotic action than the dibasic analogues such as tilmicosin, in particular good protection against Pasteurella in livestock. Tildipirosin’s interaction with the ribosomal site of action differs from that of tylosin and tilmicosin.

Uses

Tildipirosin is a novel 16-membered-ring macrolide used in veterinary medicine. Tildipirosin treats bacterial pathogens including Mannheimia haemolytica and Pasteurella multocida that cause respiratory tract infections in cattle and swine (BRD Bovine Respiratory Disease).

Biochem/physiol Actions

Tildipirosin has additionally proven effective against Histophilus somni, Bordetella bronchiseptica, Actinobacillus pleuropneumoniae, and Haemophilus parasuis, which can also be associated with animal respiratory diseases.

Mechanism of action

The mechanism of action of Tildipirosin consists of the inhibition of the bacterial protein synthesis as a consequence of binding to 23S ribosomal RNA for 50S subunit.

Side effects

In target animal safety studies, administration of the maximum recommended injection volume (5 ml) occasionally caused slight swellings at the injection site that were not painful on palpation. Swellings persisted for up to 3 days. Pathomorphological injection site reactions resolved completely within 21 days. During clinical trials, pain on injection and injection site swellings were seen very commonly in treated pigs. These swellings resolved within 1 to 6 days. During clinical trials, treatment caused shock symptoms in 2 out of 1048 animals. These symptoms quickly resolved in one animal, but led to death in the other animal.

Tildipirosin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Tildipirosin manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd

Product: Tildipirosin 328898-40-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: Customise
Release date: 2025-11-20

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Tildipirosin 328898-40-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 100kg
Release date: 2022-11-15

Henan Suikang Pharmaceutical Co.,Ltd.

Product: Tildipirosin 328898-40-4
Price: US $0.00/kg
Min. Order: 25kg
Purity: ＞98%
Supply Ability: 10tons
Release date: 2024-04-24

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tildipirosin

20-Deoxo-23-deoxy-5-O-[3,6-dideoxy-3-(dimethylamino)-beta-D-glucopyranosyl]-20,23-di-1-piperidinyltylonolide

Tildipirosin Solution, 100ppm

TIP; TILDIPIROSIN; ZUPREVO.

Zuprevo.

20-Deoxo-23-deoxy-5-O-[3,6-dideoxy-3-(dimethylamino)-beta-D-glucopyranosyl]-20,23-di-1-piperidinylty

Tylonolide, 20-deoxo-23-deoxy-5-O-[3,6-dideoxy-3-(dimethylamino)-β-D-glucopyranosyl]-20,23-di-1-piperidinyl-

Tildipirosin USP/EP/BP

TILDIPIROSIN 328898-40-4

(4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-(((2R,3R,4S,5S,6R)-4-(Dimethylamino)-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-16-ethyl-4-hydroxy-5,9,13-trimethyl-7-(2-(piperidin-1-yl)ethyl)-15-(piperidin-1-ylmethyl)oxacyclohexadeca-11,13-diene-2,10-dione

Tildipirosin in methanol

high qualtiy Tildipirosin

Tildipirosin, 10 mM in DMSO

Taijiluo Xin

Tildipirosin 98%

(4R,5S,6S,7R,9R,11E,13E,16R)-6-(((3S,4R,5R,6S)-4-(dimethylamino)-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-16-ethyl-4-hydroxy-5,9,13-trimethyl-7-(2-(piperidin-1-yl)ethyl)-15-(piperidin-1-ylmethyl)oxacyclohexadeca-11,13-diene-2,10-dione

328898-40-4

C41H71N3O8

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