Unii-p9vxv1408y
- Product Name
- Unii-p9vxv1408y
- CAS No.
- 866021-48-9
- Chemical Name
- Unii-p9vxv1408y
- Synonyms
- Ceftaroline;4-[2-[[(6R;Unii-p9vxv1408y;Ceftarolin Fosamil;Ceftaroline Impurity8;Ceftaroline USP/EP/BP;Unii-p9vxv1408y USP/EP/BP;Ceftaroline Fosamil Acetate Hydrate;7R)-2-Carboxy-7-[[(2Z)-(ethoxyimino)[5-(phosphonoamino)-1;acetic acid,(6R,7R)-7-[[(2Z)-2-ethoxyimino-2-[5-(phosphonoamino)
- CBNumber
- CB82496122
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- SML3102
- Product name
- Ceftaroline fosamil acetate hydrate
- Purity
- ≥98% (HPLC)
- Packaging
- 10MG
- Price
- $142
- Updated
- 2023/06/20
- Product number
- SML3102
- Product name
- Ceftaroline fosamil acetate hydrate
- Purity
- ≥98% (HPLC)
- Packaging
- 50MG
- Price
- $570
- Updated
- 2023/06/20
Unii-p9vxv1408y Chemical Properties,Usage,Production
Definition
ChEBI: Ceftaroline fosamil acetate monohydrate is a hydrate that is the monohydrate form of ceftaroline fosamil acetate. A prodrug for ceftaroline, used for the treatment of adults with acute bacterial skin and skin structure infections. It has a role as an antimicrobial agent, an antibacterial drug and a prodrug. It contains a ceftaroline fosamil acetate.
Antimicrobial activity
A semisynthetic cephalosporin formulated as the water-soluble fosamil acetate prodrug for intravenous administration. Its properties are similar to those of ceftobiprole, with which it shares an enhanced affinity for penicillin-binding protein 2′ (2a) of methicillin-resistant Staph. aureus. It is hydrolyzed by extended-spectrum β-lactamases and is not active against Amp-C derepressed strains of Gram-negative bacilli.
Pharmacokinetics
Cmax 600 mg intravenous (1-h infusion): 19 mg/L end infusion
Plasma half-life: 2.6 h
Volume of distribution: 0.37 L/kg
Plasma protein binding :<20%
Like ceftobiprole, ceftaroline fosamil is rapidly hydrolyzed in
plasma after intravenous infusion and excreted principally in urine.
In preliminary clinical studies it appears to be well tolerated.
Unii-p9vxv1408y Preparation Products And Raw materials
Raw materials
Preparation Products
Unii-p9vxv1408y Suppliers
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View Lastest Price from Unii-p9vxv1408y manufacturers
- Product
- ceftaroline fosamil acetate monohydrate 866021-48-9
- Price
- US $300.00/KG
- Min. Order
- 10g
- Purity
- 99%
- Supply Ability
- 500kg/month
- Release date
- 2021-12-24
- Product
- Ceftaroline fosamil 866021-48-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
- Product
- Ceftaroline 866021-48-9
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-06-29