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Unii-p9vxv1408y

Product Name
Unii-p9vxv1408y
CAS No.
866021-48-9
Chemical Name
Unii-p9vxv1408y
Synonyms
Ceftaroline;4-[2-[[(6R;Unii-p9vxv1408y;Ceftarolin Fosamil;Ceftaroline Impurity8;Ceftaroline USP/EP/BP;Unii-p9vxv1408y USP/EP/BP;Ceftaroline Fosamil Acetate Hydrate;7R)-2-Carboxy-7-[[(2Z)-(ethoxyimino)[5-(phosphonoamino)-1;acetic acid,(6R,7R)-7-[[(2Z)-2-ethoxyimino-2-[5-(phosphonoamino)
CBNumber
CB82496122
Formula Weight
0
MOL File
Mol file
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML3102
Product name
Ceftaroline fosamil acetate hydrate
Purity
≥98% (HPLC)
Packaging
10MG
Price
$142
Updated
2023/06/20
Sigma-Aldrich
Product number
SML3102
Product name
Ceftaroline fosamil acetate hydrate
Purity
≥98% (HPLC)
Packaging
50MG
Price
$570
Updated
2023/06/20
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Unii-p9vxv1408y Chemical Properties,Usage,Production

Definition

ChEBI: Ceftaroline fosamil acetate monohydrate is a hydrate that is the monohydrate form of ceftaroline fosamil acetate. A prodrug for ceftaroline, used for the treatment of adults with acute bacterial skin and skin structure infections. It has a role as an antimicrobial agent, an antibacterial drug and a prodrug. It contains a ceftaroline fosamil acetate.

Antimicrobial activity

A semisynthetic cephalosporin formulated as the water-soluble fosamil acetate prodrug for intravenous administration. Its properties are similar to those of ceftobiprole, with which it shares an enhanced affinity for penicillin-binding protein 2′ (2a) of methicillin-resistant Staph. aureus. It is hydrolyzed by extended-spectrum β-lactamases and is not active against Amp-C derepressed strains of Gram-negative bacilli.

Pharmacokinetics

Cmax 600 mg intravenous (1-h infusion): 19 mg/L end infusion
Plasma half-life: 2.6 h
Volume of distribution: 0.37 L/kg
Plasma protein binding :<20%
Like ceftobiprole, ceftaroline fosamil is rapidly hydrolyzed in plasma after intravenous infusion and excreted principally in urine. In preliminary clinical studies it appears to be well tolerated.

Unii-p9vxv1408y Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Unii-p9vxv1408y manufacturers

Hebei Mingeng Biotechnology Co., Ltd
Product
ceftaroline fosamil acetate monohydrate 866021-48-9
Price
US $300.00/KG
Min. Order
10g
Purity
99%
Supply Ability
500kg/month
Release date
2021-12-24
Zhuozhou Wenxi import and Export Co., Ltd
Product
Ceftaroline fosamil 866021-48-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11
Dideu Industries Group Limited
Product
Ceftaroline 866021-48-9
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-06-29

866021-48-9, Unii-p9vxv1408yRelated Search:

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  • Ceftaroline
  • Unii-p9vxv1408y
  • acetic acid,(6R,7R)-7-[[(2Z)-2-ethoxyimino-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-3-[[4-(1-methylpyridin-1-ium-4-yl)-1,3-thiazol-2-yl]sulfanyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate,hydrate
  • Ceftaroline Fosamil Acetate Hydrate
  • Ceftaroline Impurity8
  • 4-[2-[[(6R
  • 4-thiadiazol-3-yl]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]-4-thiazolyl]-1-methylpyridinium acetate hydrate
  • 7R)-2-Carboxy-7-[[(2Z)-(ethoxyimino)[5-(phosphonoamino)-1
  • Ceftarolin Fosamil
  • Unii-p9vxv1408y USP/EP/BP
  • Ceftaroline USP/EP/BP
  • acetic acid,(6R,7R)-7-[[(2Z)-2-ethoxyimino-2-[5-(phosphonoamino)
  • 866021-48-9
  • Amines
  • API
  • Chiral Reagents
  • Heterocycles