5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID
- Product Name
- 5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID
- CAS No.
- 128455-63-0
- Chemical Name
- 5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID
- Synonyms
- BUTTPARK 99\18-36;RARECHEM AL BO 1764;5-Chloro-1-methyl-3-(trifluoromethyl);4-Carboxy-5-chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazole;5-chloro-1-methyl-3-trifluoromethylpyrazole-4-carboxylic acid;5-chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxyl...;5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID;1H-Pyrazole-4-carboxylic acid, 5-chloro-1-methyl-3-(trifluoromethyl)-;5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylicacid97%
- CBNumber
- CB7155068
- Molecular Formula
- C6H4ClF3N2O2
- Formula Weight
- 228.56
- MOL File
- 128455-63-0.mol
5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID Property
- Melting point:
- 201 °C
- Boiling point:
- 284.4±40.0 °C(Predicted)
- Density
- 1.71±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 1.77±0.50(Predicted)
- CAS DataBase Reference
- 128455-63-0(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26
- HazardClass
- IRRITANT
- HS Code
- 2933199090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- PC6318
- Product name
- 5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylicacid
- Packaging
- 250mg
- Price
- $29
- Updated
- 2021/12/16
- Product number
- 4H21-7-09
- Product name
- 5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid
- Purity
- 97%
- Packaging
- 250mg
- Price
- $32
- Updated
- 2021/12/16
- Product number
- FC98081
- Product name
- 5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylicacid
- Packaging
- 100mg
- Price
- $40
- Updated
- 2021/12/16
- Product number
- FC98081
- Product name
- 5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylicacid
- Packaging
- 250mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- C11119
- Product name
- 5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylicacid
- Purity
- 98%
- Packaging
- 1g
- Price
- $70
- Updated
- 2021/12/16
5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID Chemical Properties,Usage,Production
Synthesis
128455-62-9
128455-63-0
Example 5: 10 g of 5-chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxaldehyde was added to 50 mL of an aqueous solution containing 5 g of sodium hydroxide (2 equivalents). Under vigorous stirring, 34.4 g of 35% hydrogen peroxide solution was slowly added in 8 drops over a temperature range of 40°C to 50°C, taking 1.5 hours. After the dropwise addition was completed, the reaction mixture was continued to be stirred for 30 minutes and subsequently cooled to 15°C. The pH of the reaction solution was adjusted to 1 with concentrated hydrochloric acid and the solid product was precipitated. The crystals were collected by filtration and washed well with water, after which the crystals were dissolved in ether. The ether solution was dried over anhydrous magnesium sulfate and decolorized by activated carbon, and then the ether was removed by distillation under reduced pressure to give 8.6 g of 5-chloro-1-methyl-3-(trifluoromethyl)pyrrole-4-carboxylic acid in 80.0% yield and 197.5-199.5 °C melting point.
References
[1] Patent: US2004/19221, 2004, A1. Location in patent: Page 7
[2] Patent: CN103951663, 2016, B. Location in patent: Paragraph 0091; 0096; 0097
[3] Journal of Heterocyclic Chemistry, 1990, vol. 27, # 2, p. 243 - 245
[4] Patent: WO2007/84868, 2007, A2. Location in patent: Page/Page column 39
[5] Journal of Heterocyclic Chemistry, 2011, vol. 48, # 2, p. 389 - 396
5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID Suppliers
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- Country
- India
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View Lastest Price from 5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID manufacturers
- Product
- 5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID 128455-63-0
- Price
- US $100.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-07-31