BRYOPOGONIC ACID

Product Name: BRYOPOGONIC ACID
CAS No.: 571-67-5
Chemical Name: BRYOPOGONIC ACID
Synonyms: NORSTICTIC ACID;BRYOPOGONIC ACID;1,3-Dihydro-1,4,10-trihydroxy-5,8-dimethyl-3,7-dioxo-7H-isobenzofuro[4,5-b][1,4]benzodioxepin-11-carbaldehyde;7H-Isobenzofuro[4,5-b][1,4]benzodioxepin-11-carboxaldehyde, 1,3-dihydro-1,4,10-trihydroxy-5,8-dimethyl-3,7-dioxo-
CBNumber: CB7155275
Molecular Formula: C18H12O9
Formula Weight: 372.28
MOL File: 571-67-5.mol

More

Less

BRYOPOGONIC ACID Property

storage temp.: Store at -20°C
solubility: DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form: A solid
color: White to off-white
LogP: 2.330 (est)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 29581
Product name: Norstictic Acid
Packaging: 1mg
Price: $178
Updated: 2024/03/01

Cayman Chemical

Product number: 29581
Product name: Norstictic Acid
Packaging: 5mg
Price: $704
Updated: 2024/03/01

AK Scientific

Product number: 1018CP
Product name: Norsticticacid
Packaging: 5mg
Price: $883
Updated: 2021/12/16

More

Less

BRYOPOGONIC ACID Chemical Properties,Usage,Production

Description

Norstictic acid is a lichen metabolite that has been found in R. farinacea and has antimicrobial and anticancer activities. It is active against A. hydrophilia, B. subtilis, L. monocytogenes, P. vulgaris, S. faecalis, C. albicans, and C. glabrata (MICs = 0.1-6.7 mM). Norstictic acid (1-100 μM) inhibits proliferation, migration, and invasion of MDA-MB-231 cells. In vivo, norstictic acid (15 mg/kg, i.p.) reduces tumor growth in an MDA-MB-231/GFP mouse xenograft model.

Anticancer Research

Norstictic acid (NA) is a depsidone-derived metabolite common in several lichenspecies of the genera Usnea, Ramalina and Parmelia. Various biological activitieshave been reported for NA including antioxidant, antimicrobial and cytotoxic innature (White et al. 2014). Recently, Ebrahim et al. (2016) reported that administrationof NA to MDA-MB-231 cells significantly suppressed the proliferation,migration and invasion. Also, it showed minimal toxicity to non-tumorigenicMCF-10A mammary epithelial cells. They also performed molecular modelling,Z′-LYTE biochemical kinase assay and Western blot analysis, to identify c-Met asa potential macromolecular target. Further, NA treatment significantly suppressedMDA-MB-231/GFP tumour growth of a BC xenograft model in athymic nudemice. At this juncture, they concluded that lichen-derived natural products arepromising resources to discover novel c-Met inhibitors useful to control TNBC(Ebrahim et al. 2016).

Anticancer Research

Norstictic acid significantlysuppressed the proliferation,migration and invasion. It alsosignificantly suppressedMDA-MB-231/GFP tumour growthof a breast cancer xenograft modelin athymic nude mice
Ebrahimet al. (2016)

BRYOPOGONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

BRYOPOGONIC ACID Suppliers

China 8 United Kingdom 1 United States 5 Global 14

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14055
Advantage: 65

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 52925
Advantage: 58

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

ChromaDex

Tel: --
Fax: --
Email: sales@chromadex.com
Country: United States
ProdList: 2501
Advantage: 76

571-67-5, BRYOPOGONIC ACIDRelated Search:

2-(3,5-DIMETHYLPHENOXY)BENZENECARBALDEHYDE 4-Acetoxy-3-methoxybenzoic acid 3-Phenoxybenzoic acid LECANORIC ACID 2,5-DIMETHYL-P-ANISALDEHYDE METHYL 5-METHOXYSALICYLATE 2,4-DIHYDROXY-3,6-DIMETHYLBENZOIC ACID METHYL 2,4-DIHYDROXY-3-METHYLBENZOATE 5-Methoxysalicylic acid METHYL 2,4-DIHYDROXY-3,6-DIMETHYLBENZOATE 2-PHENOXYBENZOIC ACID 2,5-DIMETHYL-3-HYDROXY BENZOIC ACID 3-METHOXY-5-METHYL-BENZOIC ACID METHYL ESTER 4-BENZYLOXY-2-METHYLBENZOIC ACID METHYL 6-HYDROXYVERATRATE METHYL 2-METHOXY-6-METHYLBENZOATE 2,3',5'-TRIMETHYLDIPHENYL ETHER 2,2'-BIS(HYDROXYMETHYL)DIPHENYL ETHER

NORSTICTIC ACID

BRYOPOGONIC ACID

1,3-Dihydro-1,4,10-trihydroxy-5,8-dimethyl-3,7-dioxo-7H-isobenzofuro[4,5-b][1,4]benzodioxepin-11-carbaldehyde

7H-Isobenzofuro[4,5-b][1,4]benzodioxepin-11-carboxaldehyde, 1,3-dihydro-1,4,10-trihydroxy-5,8-dimethyl-3,7-dioxo-

571-67-5

C18H12O9