ChemicalBook > CAS DataBase List >  Methyl 2-(hydroxymethyl)isonicotinate

Methyl 2-(hydroxymethyl)isonicotinate

Product Name
Methyl 2-(hydroxymethyl)isonicotinate
CAS No.
58481-17-7
Chemical Name
Methyl 2-(hydroxymethyl)isonicotinate
Synonyms
Methyl 2-(hydroxyMethyl) isonicotinate;2-Hydroxymethyl-isonicotinic acid methyl ester;Methyl 2-(hydroxymethyl)pyridine-4-carboxylate;2-(hydroxymethyl)-4-Pyridinecarboxylic acid methyl ester;4-Pyridinecarboxylic acid, 2-(hydroxyMethyl)-, Methyl ester;2-(Hydroxymethyl)Isonicotinic Acid 2(HYDROXYMETHYL)4PYRIDINECARBOXYLIC ACID
CBNumber
CB71558141
Molecular Formula
C8H9NO3
Formula Weight
167.16
MOL File
58481-17-7.mol
More
Less

Methyl 2-(hydroxymethyl)isonicotinate Property

Boiling point:
304.2±32.0 °C(Predicted)
Density 
1.244±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
13.20±0.10(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

AK Scientific
Product number
Y9548
Product name
2-(Hydroxymethyl)pyridine-4-carboxylicacid
Packaging
100mg
Price
$155
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0098187
Product name
2-HYDROXYMETHYL-ISONICOTINIC ACID METHYL ESTER
Purity
95.00%
Packaging
5MG
Price
$496.53
Updated
2021/12/16
Matrix Scientific
Product number
126639
Product name
Methyl2-(hydroxymethyl)isonicotinate
Purity
>95%
Packaging
1g
Price
$1404
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0098187
Product name
2-HYDROXYMETHYL-ISONICOTINIC ACID METHYL ESTER
Purity
95.00%
Packaging
1G
Price
$997.5
Updated
2021/12/16
Chemenu
Product number
CM121034
Product name
Methyl2-(Hydroxymethyl)pyridine-4-carboxylate
Purity
97%
Packaging
10g
Price
$1328
Updated
2021/12/16
More
Less

Methyl 2-(hydroxymethyl)isonicotinate Chemical Properties,Usage,Production

Synthesis

The reaction was performed in 2 separate 1000 mL round-bottomed flasks. To a solution of methyl isonicotinate (70 g, 510.44 mmol) and sulfuric acid (2.340 mL, 43.90 mmol) in MeOH (700 mL) under reflux added a solution of ammonium peroxydisulfate (210 g, 918.80 mmol) in water (350 mL) over 20 min. The reaction was refluxed for 20 min and was then allowed to cool to room temperature. The solid was filtered off and washed with MeOH. After that, MeOH was removed from the filtrate under reduced pressure and then neutralized by cautious stepwise addition of solid Na2CO3 under ice-cooling. The aqueous solution was extracted with ethyl acetate and the combined organic layers were dried with Na2SO4 and evaporated. The dark-brown residue was treated with cyclohexane (3×300 mL) and the cyclohexane phase was decanted. The remaining dark-brown residue was purified by automated flash chromatography on 2 Biotage KP-SIL 340 g columns. A gradient from 25% to 100% of EtOAc in heptane over 10 CV was used as the mobile phase. Methyl 2-(hydroxymethyl)isonicotinate (27.5 g, 32%) was isolated.

Methyl 2-(hydroxymethyl)isonicotinate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Methyl 2-(hydroxymethyl)isonicotinate Suppliers

China 75 India 2 United States 5 Global 82
Changzhou green chemical co., LTD
Tel
0519-82733646 13814799543
Email
sales_01@salutchem.com
Country
China
ProdList
107
Advantage
58
Suzhou Nuoouman Biological Technology Co., Ltd.
Tel
13913522962
Email
180642609@qq.com
Country
China
ProdList
4968
Advantage
58
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Chiba Pharmaceutical Science and technology Co, Ltd.
Tel
0531-81313138 13066006660
Fax
QQ: 3366077777
Email
chibapharm@foxmail.com
Country
China
ProdList
4056
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Shanghai Synmedia Chemical Co., Ltd.
Tel
021-38681880 13817889927
Fax
0213390-8196
Email
sales@synmedia-chem.com
Country
China
ProdList
249
Advantage
58
RennoTech Co., Ltd.
Tel
58353739
Fax
+86-25-58353700
Email
sales@rennotech.com
Country
China
ProdList
94
Advantage
58
DONGSHENG CHIRAL PHARMA
Tel
18051538752
Email
3755454181@qq.com
Country
China
ProdList
434
Advantage
55
Nanjing ShengSai Chemical Co., Ltd.
Tel
025-85205967 13951876367
Fax
025-85205967
Email
shengsaichem@163.com
Country
China
ProdList
811
Advantage
58
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883 15367835770
Fax
0731-82251112
Email
viola@huatengsci.com
Country
China
ProdList
5873
Advantage
58
Nanjing Chalf-Pharm Technology Co., Ltd.
Tel
025-57018978 18251899859
Fax
025-57018008
Email
sales@chalf-pharm.com
Country
China
ProdList
5800
Advantage
50
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Shanghai Amquar Biological Technology Co., Ltd.
Tel
021-51088985
Fax
021-20423591
Email
sale@amquar.com
Country
China
ProdList
89
Advantage
55
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862，442785678，326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9627
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8010
Advantage
62
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd.
Tel
027-50664929, 13971561712
Fax
027-50664927 / QQ: 3452835437
Email
hubxys2001@163.com
Country
China
ProdList
1437
Advantage
55
Wuhan Netcom Electronic Commerce Limited
Tel
18064670521
Fax
0757-88210752
Email
2355935187@ycphar.com
Country
China
ProdList
4879
Advantage
58
Jiaxing Deyi Chemical Co., Ltd.
Tel
0573-86-0573-85866609 13325730825
Fax
0573-85866609
Email
945717149@qq.com
Country
China
ProdList
8024
Advantage
58
Shanghai Baozhi Biological Technology Co., Ltd.
Tel
13764058804
Email
3438424070@qq.com
Country
China
ProdList
363
Advantage
58
Aikon International Limited
Tel
025-66113011 13155353615
Fax
(7)02557626880
Email
qzhang@aikonchem.com
Country
China
ProdList
15394
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 18016230971
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25004
Advantage
58
Shanghai ZiHao Pharmaceutical Co., Ltd.
Tel
021-13482410-12 13482410112
Fax
-
Email
362383684@qq.com
Country
China
ProdList
731
Advantage
58
Shanghai SPAR pharmaceutical technology co., LTD
Tel
021-000000
Email
admin@jingshipharmatech.com
Country
China
ProdList
9990
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52693
Advantage
58
Nanjing Asfam Pharmaceutical Technology Co., Ltd.
Tel
025-58867862 18751812725
Fax
02558867862
Email
sales@ace-pharm.com
Country
China
ProdList
1997
Advantage
58
Shanghai Gugang New Materials Technology Co. Ltd.
Tel
021-51317962
Fax
021-51317962
Email
296935822@qq.com
Country
China
ProdList
978
Advantage
58
Zhuzhou focus pharmaceutical technology co., LTD
Tel
+86-13776644403
Email
robert@focuspharma.cc
Country
China
ProdList
2300
Advantage
58
Hunan Jibang Biological Technology Co., LTD
Tel
+8613776644403
Email
sales02@kingboomtech.com
Country
China
ProdList
1804
Advantage
58
Henan Weituxi Chemical Technology Co., Ltd.
Tel
0371-63284658 18135795563
Fax
QQ:2885349392
Email
2885349392@qq.com
Country
China
ProdList
9967
Advantage
58
Amel Pharmatech Corporation
Tel
888-4366503
Fax
888-502-1736
Email
sales@amelpharmatech.com
Country
China
ProdList
4607
Advantage
58
Henan Pumei Jihua Pharmaceutical Technology Co., Ltd.
Tel
037188900765 18037465274
Fax
QQ3430974218
Email
enyawanglei@sina.cn
Country
China
ProdList
13747
Advantage
58
Chongqing Chemdad Co., Ltd
Tel
+86-023-6139-8061 +86-86-13650506873
Email
sales@chemdad.com
Country
China
ProdList
39894
Advantage
58
Shanghai Minhan Pharmaceutical Technology Co., Ltd.
Tel
176121882
Fax
QQ 2816925681
Email
2816925681@qq.com
Country
China
ProdList
2721
Advantage
58
Shanghai Kaiwei Chemical Technology Co., Ltd.
Tel
021-58461859 15821823057
Email
service@aiviche.com
Country
China
ProdList
49312
Advantage
58
career henan chemical co
Tel
+86-0371-86658258 +8613203830695
Fax
0086-371-86658258
Email
factory@coreychem.com
Country
China
ProdList
29810
Advantage
58
Fuxin Pharmaceutical
Tel
+86-021-021-50872116 +8613122107989
Email
contact@fuxinpharm.com
Country
China
ProdList
10032
Advantage
58
Hubei Co-prosperity Medicine Technonlogy Co., Ltd
Tel
2383948258 19172820304
Email
2383948258@qq.com
Country
China
ProdList
12987
Advantage
58
Beijing Stronger Science Co., Ltd.
Tel
0531-88924771 15614660963
Email
elsa.hang@strongerscience.com
Country
China
ProdList
10623
Advantage
58
JinOu Biomedical (Nanjing) Co., Ltd.
Tel
13000000000
Fax
jinoupharma@163
Email
jinoupharma@163.com
Country
China
ProdList
11721
Advantage
58
Hubei Kele Fine Chemical Co., Ltd
Tel
027-59101668 19945030958
Fax
027-59101668
Email
2881924765@qq.com
Country
China
ProdList
7890
Advantage
58
chemmole
Tel
400-168-9330 15013243073
Email
597760450@qq.com
Country
China
ProdList
2942
Advantage
58
Bide Pharmatech Ltd.
Tel
400-6005915
Email
sales@picasso-e.com
Country
China
ProdList
39665
Advantage
58
Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.
Tel
+86-027-59232304 15387063101
Email
2881924050@qq.com
Country
China
ProdList
9956
Advantage
58
Shanghai Lingfu Pharmaceutical Research Co. LTD
Tel
400-8675577 19945755304
Email
sales@chemany.com
Country
China
ProdList
9943
Advantage
58
Pushan Industry (Shaanxi) Co., Ltd.
Tel
029-81310890 13571859809
Email
info@pushanshiye.com
Country
China
ProdList
10000
Advantage
58
Henan Dowon Chemical Technology Co., Ltd.
Tel
16696119288
Email
779113375@qq.com
Country
China
ProdList
7627
Advantage
58
More
Less

View Lastest Price from Methyl 2-(hydroxymethyl)isonicotinate manufacturers

Career Henan Chemical Co
Product
2-Hydroxymethyl-isonicotinic acid methyl ester 58481-17-7
Price
US $6.68/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg-1000kg
Release date
2020-01-08

58481-17-7, Methyl 2-(hydroxymethyl)isonicotinateRelated Search:


  • 2-Hydroxymethyl-isonicotinic acid methyl ester
  • 4-Pyridinecarboxylic acid, 2-(hydroxyMethyl)-, Methyl ester
  • 2-(Hydroxymethyl)Isonicotinic Acid 2(HYDROXYMETHYL)4PYRIDINECARBOXYLIC ACID
  • Methyl 2-(hydroxyMethyl) isonicotinate
  • Methyl 2-(hydroxymethyl)pyridine-4-carboxylate
  • 2-(hydroxymethyl)-4-Pyridinecarboxylic acid methyl ester
  • 58481-17-7