ChemicalBook > CAS DataBase List > 5-Trifluoromethyl-pyridine-2-carbaldehyde

5-Trifluoromethyl-pyridine-2-carbaldehyde

Product Name: 5-Trifluoromethyl-pyridine-2-carbaldehyde
CAS No.: 31224-82-5
Chemical Name: 5-Trifluoromethyl-pyridine-2-carbaldehyde
Synonyms: 5-(trifluoromethyl)picolinaldehyde;Picolinaldehyde, 5-(trifluoromethyl)-;5-Trifluoromethyl-2-pyridinecarbaldehyde;5-Trifluoromethyl-pyridine-2-carbaldehyde;5-trifluoromethyl pyridine-2-formaldehyde;2-Pyridinecarboxaldehyde, 5-(trifluoromethyl)-;5-(Trifluoromethyl)pyridine-2-carboxaldehyde,95%;5-Trifluoromethyl-pyridine-2-carbaldehyde ISO 9001：2015 REACH;5-Trifluoromethyl-Pyridine-2-Carbaldehyde 5-Trifluoromethyl-Pyridine-2-Carbaldehyde
CBNumber: CB71560087
Molecular Formula: C7H4F3NO
Formula Weight: 175.11
MOL File: 31224-82-5.mol

Less

5-Trifluoromethyl-pyridine-2-carbaldehyde Property

Melting point:: 31-33℃
Boiling point:: 197.5±40.0 °C(Predicted)
Density: 1.369±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 1.30±0.10(Predicted)
Appearance: White to off-white Solid-liquid mixture
Sensitive: Air Sensitive
InChI: InChI=1S/C7H4F3NO/c8-7(9,10)5-1-2-6(4-12)11-3-5/h1-4H
InChIKey: JJDDVGAESNBKMY-UHFFFAOYSA-N
SMILES: C1(C=O)=NC=C(C(F)(F)F)C=C1

Less

Safety

HazardClass: IRRITANT, AIR SENSITIVE
HS Code: 2933399990

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

Less

N-Bromosuccinimide Price

Oakwood

Product number: 038146
Product name: 5-(Trifluoromethyl)-pyridine-2-carboxaldehyde
Packaging: 250mg
Price: $82
Updated: 2021/12/16

Apolloscientific

Product number: PC201227
Product name: 5-(Trifluoromethyl)-2-pyridinecarboxyaldehyde
Purity: 95+%
Packaging: 250mg
Price: $89
Updated: 2021/12/16

Matrix Scientific

Product number: 032348
Product name: 5-(Trifluoromethyl)pyridine-2-carboxaldehyde
Purity: 95%
Packaging: 500mg
Price: $130
Updated: 2021/12/16

Matrix Scientific

Product number: 032348
Product name: 5-(Trifluoromethyl)pyridine-2-carboxaldehyde
Purity: 95%
Packaging: 1g
Price: $195
Updated: 2021/12/16

Oakwood

Product number: 038146
Product name: 5-(Trifluoromethyl)-pyridine-2-carboxaldehyde
Packaging: 1g
Price: $206
Updated: 2021/12/16

Less

5-Trifluoromethyl-pyridine-2-carbaldehyde Chemical Properties,Usage,Production

Synthesis

31181-84-7

31224-82-5

General procedure for the synthesis of 5-trifluoromethylpyridine-2-carboxaldehyde from 5-trifluoromethylpyridine-2-methanol: A dichloromethane (10 mL) solution of Example 34B (3.89 g, 22.0 mmol) was added to a dichloromethane (10 mL) solution of Dess-Martin periodinane (1 ,1,1-tris(acetyloxy)-1,1-dihydro-1,2-benziodioxo heterocyclopentan-3(1H)-one, 10.3 g, 24.2 mmol) in a solution of dichloromethane (73 mL). The reaction mixture was stirred at room temperature for about 20 minutes under nitrogen protection until a solid was formed. The reaction mixture was diluted with 50 mL of dichloromethane and about 30 mL of saturated sodium bicarbonate solution was carefully added to quench the reaction. The undissolved solid was removed by filtration and the filtrate was transferred to a partition funnel. The aqueous phase was extracted with dichloromethane and the combined organic layers were washed with brine, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to 50 mL. The concentrate was purified by passing it through a silica gel column (Analogix? 40 x 150 mm) using 25% to 50% ethyl acetate/hexanes as eluent. 2.86 g (74% yield) of 5-trifluoromethylpyridine-2-carboxaldehyde was finally obtained as a clear oil, which solidified on standing.1H NMR (300 MHz, CDCl3) δ 10.15 (s, 1H), 9.06 (m, 1H), 8.15 (m, 1H), 8.09 (d, J=8.1 Hz, 1H).

References

[1] Patent: US2009/124666, 2009, A1. Location in patent: Page/Page column 26
[2] Patent: US2006/223837, 2006, A1. Location in patent: Page/Page column 35
[3] Patent: US2015/232460, 2015, A1. Location in patent: Paragraph 0478-0480

5-Trifluoromethyl-pyridine-2-carbaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

Less

5-Trifluoromethyl-pyridine-2-carbaldehyde Suppliers

China 115 India 3 United States 9 Global 127

Hangzhou Copiore Chemical Co., Ltd.

Tel: 0571-56501939;0571-56076030 13757145729
Fax: 0571-56501939
Email: sales@copiore.com
Country: China
ProdList: 299
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Changzhou Huanling Chemical Co., Ltd.

Tel: 0519-89803565 13776850645
Fax: 0519-89803575
Email: info4@huanlingchem.com
Country: China
ProdList: 891
Advantage: 68

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

Beijing Eternalchem Co,. Ltd.

Tel: 010-59484199 18611897322
Email: sales@eternalchem.com
Country: China
ProdList: 4383
Advantage: 60

Shanghai yirong biology science and technology co., ltd

Tel: 18049974220
Fax: +86 (21) 51062076
Email: 3060526242@qq.com
Country: China
ProdList: 995
Advantage: 60

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

SynAsst Chemical.

Tel: 021-60343070
Fax: 021-35122006
Country: China
ProdList: 12740
Advantage: 55

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Taizhou Yikang Chemical Co., Ltd.

Tel: 0576-88501337 18906763631
Fax: +86-576-88501337
Email: sales@yikangchemicals.com
Country: China
ProdList: 270
Advantage: 58

Shanghai Aspire Biological Technology Co., Ltd.

Tel: 021-61317773
Fax: 021-61486878
Email: sales@aspirebio.com
Country: China
ProdList: 2880
Advantage: 58

Shanghai Taifu Pharmaceutical Technology Co. LTD

Tel: 021-58111238 18930958102
Fax: 021-58111238
Email: sales@taifupharm.com
Country: China
ProdList: 509
Advantage: 55

NINGBO INNO PHARMCHEM CO.,LTD.

Tel: 86-574-27787657
Fax: 86-574-27912196
Email: info@dearchem.com
Country: China
ProdList: 4613
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66028182 18626450290
Email: yftan@aikonchem.com
Country: China
ProdList: 16679
Advantage: 50

Cool Pharm, Ltd

Tel: 021-60455363 18019463053
Fax: 50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12346
Advantage: 58

Hangzhou Milestone Pharmtech Co., Ltd.

Tel: 0571-82896630 18969958410
Email: sales_hz@milestonepharmtech.com
Country: China
ProdList: 4894
Advantage: 55

Nanjing Huang Tai Pharmaceutical Technology Co. Ltd.

Tel: 025-58803135 18551845925
Fax: 025-58803650
Email: 3569572487@qq.com
Country: China
ProdList: 337
Advantage: 58

NovoChemy Ltd.

Tel: 86-(0)21-31261262 373522135
Fax: 86-(0)21-33250524
Email: sales@novochemy.com
Country: China
ProdList: 6498
Advantage: 58

JW & Y Pharmlab Co., Ltd.

Tel: 021-64340559 13651849907;
Fax: 021- 64345308
Email: xinyu_shi@jwypharmlab.com.cn
Country: China
ProdList: 12000
Advantage: 58

Shanghai Chenzhu Pharmaceutical Co., Ltd.

Tel: 13162380607
Fax: QQ:1696175688
Email: 1696175688@qq.com
Country: China
ProdList: 817
Advantage: 55

Shanghai Carlow Chemicals Co., Ltd.

Tel: 21-33526724 18930996265
Fax: +86 21 37023730
Email: info@carlowchem.com
Country: China
ProdList: 1969
Advantage: 50

SuZhou ShiYa Biopharmaceuticals, Inc.

Tel: 0512-0512-52358471 17715136450
Fax: 05125235 6881
Email: sales@shiyabiopharm.com
Country: China
ProdList: 12127
Advantage: 58

Zhengzhou Alfachem Co.,Ltd.

Tel: 0371-53778726 18003825608
Fax: QQ：2885354392
Email: liuxiaoyan@alfachem.cn
Country: China
ProdList: 1986
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Suzhou JingTong Pharmaceutical Co., Ltd.

Tel: 13675155016
Fax: 18912765016
Email: tongtf110@sina.com
Country: China
ProdList: 963
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Nanjing Klender Bio-Technology Co., Ltd.

Tel: 025-52343882 18112933882
Fax: 025-52343882
Email: sales@kldbio.com
Country: China
ProdList: 2019
Advantage: 55

Nanijing m&m biotechnology Co. ,Ltd.

Tel: 025-87782433 18021532344
Fax: 025-87782433
Email: 1345332203@qq.com
Country: China
ProdList: 4134
Advantage: 58

Shandong Ono Chemical Co., Ltd.

Tel: 0539-6362799 20）
Fax: 0539-6362799（To 20）
Country: China
ProdList: 10007
Advantage: 58

Sichuan BaiPeng Biotechnology Co., Ltd.

Tel: 028-65791793 18140026355
Fax: QQ568470422
Email: 568470422@qq.com
Country: China
ProdList: 9997
Advantage: 58

Shanghai WangFa Chemical Technology Co., Ltd.

Tel: 13918479294
Fax: -
Email: xiebenfa@163.com
Country: China
ProdList: 4090
Advantage: 58

Suzhou Nuoouman Biological Technology Co., Ltd.

Tel: 15026866316
Email: 180642609@qq.com
Country: China
ProdList: 4967
Advantage: 58

SHANGHAI FDC-CHEMICAL CO.,LTD

Tel: 021-61469567 13482353728
Fax: 021-61161605
Email: sales@fdc-chemical.com
Country: China
ProdList: 9717
Advantage: 58

Rhawn Reagent

Tel: 400-400-1332688 18019345275
Fax: 400-133-2688
Email: amy@rhawn.cn
Country: China
ProdList: 14948
Advantage: 58

Bejing Famous Pharmaceutical Technology Co., Ltd.

Tel: 13331045123
Fax: 86-10-80339217
Email: 2559355526@qq.com
Country: China
ProdList: 14193
Advantage: 58

Hebei Huaxing Chemical Co., Ltd

Tel: 0319-6931777 13930968617
Fax: +86-319-6931577
Email: 630669494@qq.com
Country: China
ProdList: 1021
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Zhengzhou Ruke Biological Co., Ltd.

Tel: 15981811963
Fax: QQ：1410472904
Email: 1410472904@qq.com
Country: China
ProdList: 5825
Advantage: 58

Shanghai HongMin Pharmaceutical Co., Ltd.

Tel: 13651987816
Fax: -
Email: hongminpharm@163.com
Country: China
ProdList: 2326
Advantage: 58

Shanghai SPAR pharmaceutical technology co., LTD

Tel: 021-000000 13917643586;
Email: admin@jingshipharmatech.com
Country: China
ProdList: 9856
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Nanjing Meihao Pharmaceutical Technology Co., Ltd.

Tel: meitaochem@126.com
Email: meitaochem@126.com
Country: China
ProdList: 19103
Advantage: 58

Allfluoro pharmaceutical co. ltd.

Tel: +86-400-0216110 +86-15958047586
Fax: 0086-21-33275002
Email: sales@allfluoro.com
Country: China
ProdList: 11385
Advantage: 58

ANHUI WITOP BIOTECH CO., LTD

Tel: +8615255079626
Email: eric@witopchemical.com
Country: China
ProdList: 23541
Advantage: 58

Labnetwork lnc.

Tel: +86-27-50766799 +8618062016861
Email: contact@labnetwork.com
Country: China
ProdList: 19987
Advantage: 58

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 20284
Advantage: 58

Less

View Lastest Price from 5-Trifluoromethyl-pyridine-2-carbaldehyde manufacturers

PNP Biotech Co. Ltd

Product: 5-(Trifluoromethyl)-2-pyridinecarboxyaldehyde 31224-82-5
Price: US $0.00/kg
Min. Order: 25kg
Purity: 98%
Supply Ability: Inquiry
Release date: 2023-07-13

Dideu Industries Group Limited

Product: 5-Trifluoromethyl-pyridine-2-carbaldehyde 31224-82-5
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-08-31

Career Henan Chemical Co

Product: 5-Trifluoromethyl-pyridine-2-carbaldehyde 31224-82-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2019-12-31

31224-82-5, 5-Trifluoromethyl-pyridine-2-carbaldehydeRelated Search:

5-Trifluoromethyl-pyridine-2-carbaldehyde

5-(trifluoromethyl)picolinaldehyde

5-Trifluoromethyl-Pyridine-2-Carbaldehyde 5-Trifluoromethyl-Pyridine-2-Carbaldehyde

Picolinaldehyde, 5-(trifluoromethyl)-

5-Trifluoromethyl-2-pyridinecarbaldehyde

2-Pyridinecarboxaldehyde, 5-(trifluoromethyl)-

5-(Trifluoromethyl)pyridine-2-carboxaldehyde,95%

5-Trifluoromethyl-pyridine-2-carbaldehyde ISO 9001：2015 REACH

5-trifluoromethyl pyridine-2-formaldehyde

31224-82-5