BOC-D-DAP-OH

Product Name: BOC-D-DAP-OH
CAS No.: 76387-70-7
Chemical Name: BOC-D-DAP-OH
Synonyms: BOC-D-2,3-DIAMINOPROPIONIC ACID;BOC-D-DAP-OH;BOC-D-DAPA-OH;BOC-D-DAP-OH 98%;3-AMino-N-Boc-D-alanine;76387-70-7 BOC-D-DAP-OH;N-t-BOC-?amino-D-alanine;3-Amino-N-N-BOC-D-alanine;N-Boc-beta-Amino-D-alanine;N-T-BOC-BETA-AMINO-D-ALANINE
CBNumber: CB7161245
Molecular Formula: C8H16N2O4
Formula Weight: 204.22
MOL File: 76387-70-7.mol

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BOC-D-DAP-OH Property

Melting point:: 200-203℃
Boiling point:: 364.4±37.0 °C(Predicted)
Density: 1.189±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
pka: 2.88±0.16(Predicted)
form: solid
color: White
optical activity: Consistent with structure
InChI: InChI=1S/C8H16N2O4/c1-8(2,3)14-7(13)10-5(4-9)6(11)12/h5H,4,9H2,1-3H3,(H,10,13)(H,11,12)/t5-/m1/s1
InChIKey: KRJLRVZLNABMAT-RXMQYKEDSA-N
SMILES: C(O)(=O)[C@@H](CN)NC(OC(C)(C)C)=O

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Safety

HazardClass: IRRITANT
HS Code: 29225090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: B201728
Product name: BOC-D-DAP-OH
Packaging: 100mg
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB48822
Product name: N-alpha-Boc-D-2,3-diaminopropionic acid
Packaging: 500mg
Price: $60
Updated: 2021/12/16

Apolloscientific

Product number: OR307061
Product name: 3-Amino-N-(tert-butoxycarbonyl)-D-alanine
Packaging: 5g
Price: $64
Updated: 2021/12/16

Matrix Scientific

Product number: 041453
Product name: Boc-D-Dap-OH
Packaging: 5g
Price: $83
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H57-1-R6
Product name: 3-Amino-N-(tert-butoxycarbonyl)-D-alanine
Packaging: 5G
Price: $88
Updated: 2021/12/16

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BOC-D-DAP-OH Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Uses

N(alpha)-Boc-D-2,3-diaminopropionic acid is used as pharmaceutical intermediate.

Synthesis

7536-55-2

76387-70-7

N-Boc-L-asparagine (13; 3.48 g, 15 mmol) was used as starting material, which was co-dissolved with PIDA (5.81 g, 18 mmol) in a solvent mixture of EtOAc, MeCN, and H2O (2:2:1, v/v, total volume 62.5 mL). The reaction was carried out at 16°C for 30 min. Subsequently, the reaction system was slowly warmed to room temperature and stirring was continued for 4 hours. A precipitate was generated during the reaction, which was collected by filtration and dried to afford the target product (R)-3-amino-2-((tert-butoxycarbonyl)amino)propionic acid in a yield of 2.02 g (66% yield, 9.89 mmol) as a colorless solid with a melting point of 211-213 °C (literature value 216 °C). The product was confirmed by 1H NMR (500 MHz, DMSO-d6): δ= 1.40 [s, 9H, C(CH3)3], 2.76 (dd, 3J = 9.2 Hz, 2J = 11.8 Hz, 1H, CH2), 3.06 (dd, 3J = 5.1 Hz, 2J = 11.8 Hz, 1H, CH2), 3.65-3.69 (m 1H, COCH), 6.08 (s, 1H, OCONH). No proton signals were observed for the COOH and NH2 groups.13C NMR (125 MHz, DMSO-d6) data: δ = 28.3, 40.8, 51.1, 78.2, 155.2, 171.2. LC-MS (ESI) analysis showed 100% purity of the product; m/z = 205.19 ([M + H]+), 203.09 ([ M - H]-). HRMS (ESI+) analysis results: calculated value C8H16N2O4 ([M + H]+) m/z = 205.1183; measured value: 205.1177.

References

[1] Organic and Biomolecular Chemistry, 2015, vol. 13, # 6, p. 1629 - 1633
[2] Chemical Communications, 2011, vol. 47, # 4, p. 1198 - 1200
[3] Journal of Organic Chemistry, 2012, vol. 77, # 13, p. 5696 - 5704
[4] Synlett, 2008, # 4, p. 513 - 516
[5] Journal of Peptide Science, 2017, vol. 23, # 3, p. 202 - 214

BOC-D-DAP-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-D-DAP-OH Suppliers

Canada 1 China 171 France 1 Germany 5 India 2 Japan 2 Switzerland 1 United Kingdom 3 United States 15 Global 201

Sichuan jiayinglai technology CO.,LTD

Tel: 9018 15982359653
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Suzhou Biosyntech Co., Ltd.

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J & K SCIENTIFIC LTD.

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Meryer (Shanghai) Chemical Technology Co., Ltd.

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Alfa Aesar

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Email: saleschina@alfa-asia.com
Country: China
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Energy Chemical

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Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
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Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
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Beijing Ouhe Technology Co., Ltd

Tel: 13552068683 13522913783
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Jia Xing Isenchem Co.,Ltd

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View Lastest Price from BOC-D-DAP-OH manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Boc-D-Dap-OH 76387-70-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T+
Release date: 2023-09-23

Sichuan Jiaying Lai Technology Co.,LTD

Product: Boc-D-Dap-OH 76387-70-7
Price: US $1.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 100KG
Release date: 2019-07-19

Career Henan Chemical Co

Product: BOC-D-DAP-OH 76387-70-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 10KG
Release date: 2019-08-05

76387-70-7, BOC-D-DAP-OHRelated Search:

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N-ALPHA-BOC-D-2,3-DIAMINOPROPIONIC ACID

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N-ALPHA-TERT-BUTYLOXYCARBONYL-D-2,3-DIAMINOPROPIONIC ACID

N-ALPHA-T-BUTOXYCARBONYL-D-2,3-DIAMINOPROPIONIC ACID

N-T-BOC-BETA-AMINO-D-ALANINE

N-t-BOC-?amino-D-alanine

N-α-Boc-D-2,3-diaminopropionic acid

a-N-tert-butoxycarbonyl-b-amino-L-alanine

N-Boc-beta-Amino-D-alanine

N-TERT-BOC-BETA-AMINO-D-ALANINE

N-ALPHA-T-BUTYLOXYCARBONYL-D-2,3-DIAMINOPROPIONIC ACID

N-A -BOC-D-2,3-DIAMINOPROPIONIC ACID

N2-BOC-R-2,3-DIAMINOPROPIONIC ACID

Boc-D-Dap-OH(Na-Boc-D-2,3-DiaMinopropionic acid)

BOC-D-ALPHA,BETA-DIAMINOPROPIONIC ACID

BOC-D-DAP-OH

BOC-D-DAPA-OH

(R)-3-AMino-2-((tert-butoxycarbonyl)aMino)propanoic acid

(2R)-3-amino-2-{[(tert-butoxy)carbonyl]amino}propanoic acid

3-AMino-N-Boc-D-alanine

3-Amino-N-(tert-butoxycarbonyl)-D-alanine

N<sup>α</sup>-Boc-D-2,3-diaMinopropionic acid

(Tert-Butoxy)Carbonyl D-Dap-OH

(2R)-3-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoicacid

D-Alanine,3-aMino-N-[(1,1-diMethylethoxy)carbonyl]-

Na-Boc-(R)-2,3-diaminopropionic acid

Nα-Boc-D-2,3-diaminopropionic acid≥ 99% (Titration)

BOC-D-2,3-DIAMINOPROPIONIC ACI

(R)-2-(Aminomethyl)-4-(tert-butoxy)-4-oxobutanoicacid

N(^a)-Boc-D-2,3-diaminopropionicacid,97%

76387-70-7 BOC-D-DAP-OH

3-Amino-N-[(1,1-dimethylethoxy)carbonyl]-D-alanine

BOC-D-DAP-OH 98%

3-Amino-N-N-BOC-D-alanine

(R)-2-tert-butoxycarbonyl-3-aminopropionic acid

BOC-D-2,3-DIAMINOPROPIONIC ACID

76387-70-7