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BREVETOXIN B

Product Name
BREVETOXIN B
CAS No.
79580-28-2
Chemical Name
BREVETOXIN B
Synonyms
gb2;t4-7;btx-b;PBTX-2;GBTX-2;gb2toxin;toxint-34;t4-7toxin;BREVETOXIN B;BREVETOXIN 2
CBNumber
CB7161922
Molecular Formula
C50H70O14
Formula Weight
895.08
MOL File
79580-28-2.mol
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BREVETOXIN B Property

Melting point:
270(Disassembly)
Density 
1.188±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Ethyl Acetate: soluble
form 
A film
pka
13.72±0.70(Predicted)
optical activity
+154.022 (CHCl3)
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Safety

Hazard Codes 
T+
Risk Statements 
26/27/28
Safety Statements 
22-36/37/39-45
RIDADR 
UN 2811 6.1/PG 2
WGK Germany 
3
RTECS 
XW5886000
HazardClass 
6.1(a)
PackingGroup 
I
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
203732
Product name
Brevetoxin PbTx-2, Ptychodiscus brevis - CAS 79580-28-2 - Calbiochem
Purity
Lipid-solublepolyetherneurotoxinthatbindstoNa+channelsonnervesandmusc
Packaging
100μg
Price
$712
Updated
2024/03/01
Cayman Chemical
Product number
10011498
Product name
Brevetoxin B
Purity
≥95%
Packaging
100μg
Price
$275
Updated
2024/03/01
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BREVETOXIN B Chemical Properties,Usage,Production

Description

Brevetoxin B is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. It binds to site 5 on the alpha subunit of voltage-gated sodium channels (IC50 = 15 nM) on neurons at the neuromuscular junction, causing the channel to open irreversibly at potentials more negative than normal, discharging action potentials repetitively. Brevetoxin B is ichthyotoxic at nanomolar concentrations and is responsible for an illness described as neurotoxic shellfish poisoning.

Definition

ChEBI: Brevetoxin B is a ciguatoxin.

BREVETOXIN B Preparation Products And Raw materials

Raw materials

Preparation Products

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BREVETOXIN B Suppliers

China 33 France 1 Germany 1 India 1 Switzerland 1 United Kingdom 1 United States 8 Global 46
SIGMA-RBI
Tel
--
Fax
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Country
Switzerland
ProdList
6896
Advantage
91

79580-28-2, BREVETOXIN BRelated Search:

TRI(PROPYLENE GLYCOL) PROPYL ETHER 5,6-DIHYDRO-2H-PYRAN-2-ONE TETRAETHYLENE GLYCOL MONOTETRADECYL ETHER OCTAETHYLENE GLYCOL 2-(2-Ethoxyethoxy)ethyl acrylate HEXAETHYLENE GLYCOL MONODECYL ETHER HEXAETHYLENE GLYCOL MONODODECYL ETHER Nonaethylene glycol Octadecyl acrylate BEHENYL ACRYLATE Decaethylene glycol C16E4 C10 E8 CIS-2-METHYL-7-OCTADECENE OCTAETHYLENE GLYCOL MONOMETHYL ETHER NONAETHYLENE GLYCOL MONOMETHYL ETHER BREVETOXIN B 3-METHOXYBUTYL ACRYLATE

  • PBTX-2
  • brevetoxint34
  • btx-b
  • gb2
  • gb2toxin
  • t4-7
  • t4-7toxin
  • toxint-34
  • BREVETOXIN 2
  • BREVETOXIN B
  • BREVETOXIN PBTX-2
  • BREVETOXIN PBTX-2, PTYCHODISCUS BREVIS
  • GBTX-2
  • Brevetoxinpbtx-2-20c
  • 1H-Pyrano(2'',3'':5',6')pyrano(2',3':5,6)pyrano(3,2-B)pyrano(2'''''',3'''''':5''''',6''''')pyrano(2''''',3''''':5'''',6'''')pyrano(2'''',3'''':6''',7''')oxepino(2''',3''':6'',7'')oxepino(2'',3'':5',6')pyrano(2',3':5,6)pyrano(2,3-G)oxocin-3-propanal, 2,3,4A,5,5A,6A,9,9A,10A,11,11A,12A,13,14,14A,15A,16,16A,18,20A,21A,22,22A,23A,24,25,25A,26A,27,27A,28A,29,29A,30A-tetratriacontahydro-1-hydroxy-9A,13,20,21A,25A,26A,30A-heptamethyl-alpha-methylene-18-oxo-, (1S-(1alpha,3alpha,4aalpha,5aalpha,6aalpha,9aalpha,10aalpha, 11aalpha,12aalpha,13beta,14aalpha,15aalpha,16aalpha,20abeta, 21abeta,22abeta,23abet
  • Gb 2 (gymnodinium)
  • 79580-28-2
  • C30H22O12
  • C50H70O14
  • BioChemical
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Other Sodium Channel Modulators
  • Voltage-gated Ion Channels
  • Sodium Channel Modulators
  • Ion Channels
  • Monovalent Ion Channels