2-AMINO-5-(2-CHLOROPHENYL)-1,3,4-THIADIAZOLE

Product Name: 2-AMINO-5-(2-CHLOROPHENYL)-1,3,4-THIADIAZOLE
CAS No.: 828-81-9
Chemical Name: 2-AMINO-5-(2-CHLOROPHENYL)-1,3,4-THIADIAZOLE
Synonyms: 5-(2-Chlorophenyl);VITAS-BB TBB000090;IFLAB-BB F1386-0067;5-(2-CHLOROPHENYL)-1,3,4-THIADIAZOL-2-AMINE;2-AMINO-5-(2-CHLOROPHENYL)-1,3,4-THIADIAZOLE;1,3,4-Thiadiazol-2-aMine, 5-(2-chlorophenyl)-;5-(2-CHLORO-PHENYL)-[1,3,4]THIADIAZOL-2-YLAMINE
CBNumber: CB7162141
Molecular Formula: C8H6ClN3S
Formula Weight: 211.67
MOL File: 828-81-9.mol

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2-AMINO-5-(2-CHLOROPHENYL)-1,3,4-THIADIAZOLE Property

Melting point:: 192-195 °C
Boiling point:: 393.8±44.0 °C(Predicted)
Density: 1.461±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
form: solid
pka: 2.28±0.10(Predicted)
Appearance: Light yellow to brown Solid
InChI: 1S/C8H6ClN3S/c9-6-4-2-1-3-5(6)7-11-12-8(10)13-7/h1-4H,(H2,10,12)
InChIKey: JKSGNHRIXMYPIO-UHFFFAOYSA-N
SMILES: Nc1nnc(s1)-c2ccccc2Cl

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Safety

Hazard Codes: Xi,T
Risk Statements: 25
Safety Statements: 45
WGK Germany: WGK 3
HazardClass: IRRITANT
Storage Class: 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications: Acute Tox. 3 Oral

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

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N-Bromosuccinimide Price

TRC

Product number: C350815
Product name: 5-(2-Chlorophenyl)-1,3,4-thiadiazol-2-amine
Packaging: 250mg
Price: $75
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0033140
Product name: 2-AMINO-5-(2-CHLOROPHENYL)-1,3,4-THIADIAZOLE
Purity: 95.00%
Packaging: 1G
Price: $721.57
Updated: 2021/12/16

AK Scientific

Product number: V7899
Product name: 5-(2-Chlorophenyl)-1,3,4-thiadiazol-2-amine
Packaging: 10g
Price: $824
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0033140
Product name: 2-AMINO-5-(2-CHLOROPHENYL)-1,3,4-THIADIAZOLE
Purity: 95.00%
Packaging: 2.5G
Price: $983.88
Updated: 2021/12/16

Matrix Scientific

Product number: 009946
Product name: 5-(2-Chloro-phenyl)-[1,3,4]thiadiazol-2-ylamine
Packaging: 1g
Price: $113
Updated: 2021/12/16

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2-AMINO-5-(2-CHLOROPHENYL)-1,3,4-THIADIAZOLE Chemical Properties,Usage,Production

Synthesis

79-19-6

118-91-2

828-81-9

5.1.1 Synthesis of 5-(2-chlorophenyl)-1,3,4-thiadiazol-2-amine (68): 2-chlorobenzoic acid (5.18 g, 25 mmol) and aminothiourea (2.28 g, 25 mmol) were dissolved in POCl3 (7 ml) and stirred vigorously for 0.5 hr at 75 °C. After completion of the reaction, H2O (30 ml) was added and the mixture was heated to reflux for 4 hours. Subsequently, the reaction mixture was adjusted with 50% NaOH solution to pH 8. The precipitate was collected by filtration and the filter cake was purified by recrystallization from ethanol to give the yellow crystalline product 68 in a yield of 3.90 g, 88% yield, melting point 190-192 °C (EtOH). The product was analyzed by ESI-MS, m/z: 212.1 [M + H]+; 1H NMR (CDCl3) δ 7.45-7.50 (m, 4H), 7.60-7.62 (m, 1H), 7.99-8.01 (m, 1H). Compounds 60-81 were synthesized in the same way.

References

[1] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1999, vol. 38, # 8, p. 998 - 1001
[2] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 21, p. 5766 - 5775
[3] Medicinal Chemistry Research, 2018, vol. 27, # 7, p. 1800 - 1821
[4] Medicinal Chemistry Research, 2012, vol. 21, # 6, p. 816 - 824
[5] Journal of Chemical Research, 2014, vol. 38, # 6, p. 347 - 350

2-AMINO-5-(2-CHLOROPHENYL)-1,3,4-THIADIAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-5-(2-CHLOROPHENYL)-1,3,4-THIADIAZOLE Suppliers

Canada 1 China 32 France 1 India 1 Russia 3 Ukraine 1 United Kingdom 2 United States 5 Global 46

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ANHUI WITOP BIOTECH CO., LTD

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Suzhou Victorypharm Co.,Ltd.

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View Lastest Price from 2-AMINO-5-(2-CHLOROPHENYL)-1,3,4-THIADIAZOLE manufacturers

Honest Joy Holdings Limited

Product: 5-(2-Chlorophenyl)-1,3,4-thiadiazol-2-amine 828-81-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97.6%
Supply Ability: 100 tons
Release date: 2022-02-20

828-81-9, 2-AMINO-5-(2-CHLOROPHENYL)-1,3,4-THIADIAZOLERelated Search:

2-AMINO-5-(4-CHLOROPHENYL)-1,3,4-THIADIAZOLE 2-AMINO-5-(4-CHLOROPHENYL)-1 3 4- 5-Amino-3-(4-chlorophenyl)-1,2,4-thiadiazole 2-AMINO-5-(2,4-DICHLOROPHENYL)-1,3,4-THIADIAZOLE 2-AMINO-5-(2-CHLOROPHENYL)-1,3,4-THIADIAZOLE 5-(2,6-dichlorophenyl)-1,3,4-thiadiazol-2-amine 5-(2,5-dichlorophenyl)-1,3,4-thiadiazol-2-amine 5-(2-CHLORO-5-NITRO-PHENYL)-[1,3,4]THIADIAZOL-2-YLAMINE 5-(2-CHLORO-4-NITRO-PHENYL)-[1,3,4]THIADIAZOL-2-YLAMINE 5-(2-chloro-4-fluorophenyl)-1,3,4-thiadiazol-2-amine 5-(2,4-DICHLOROPHENYL)-1,3,4-THIADIAZOL-2-YLAMINE HYDROCHLORIDE 5-(2,3-dichlorophenyl)-1,3,4-thiadiazol-2-amine 5-(2-chloro-6-fluorophenyl)-1,3,4-thiadiazol-2-amine

VITAS-BB TBB000090

IFLAB-BB F1386-0067

5-(2-CHLOROPHENYL)-1,3,4-THIADIAZOL-2-AMINE

5-(2-CHLORO-PHENYL)-[1,3,4]THIADIAZOL-2-YLAMINE

2-AMINO-5-(2-CHLOROPHENYL)-1,3,4-THIADIAZOLE

5-(2-Chlorophenyl)

1,3,4-Thiadiazol-2-aMine, 5-(2-chlorophenyl)-

828-81-9