Picotamide

Product Name: Picotamide
CAS No.: 32828-81-2
Chemical Name: Picotamide
Synonyms: g137;PICOTAMIDE;N,N’-Bis(3-Pyridinylmethyl)-4-Me;n,n’-bis(3-picolyl)-4-methoxyisophthalamide;4-methoxy-n,n’-bis(3-pyridylmethyl)isophthalamide;4-methoxy-n,n’-bis(3-pyridylmethyl)-isophthalamid;4-methoxy-N,N'-bis(3-pyridylmethyl)isophthaldiamide;Isophthalamide, 4-methoxy-N,N'-bis(3-pyridylmethyl)-;n,n’-bis(3-pyridinylmethyl)-4-methoxy-3-benzenedicarboxamide;4-METHOXY-N,N'-BIS(3-PYRIDINYLMETHYL)-1,3-BENZENEDICARBOXAMIDE
CBNumber: CB7167904
Molecular Formula: C21H20N4O3
Formula Weight: 376.41
MOL File: 32828-81-2.mol

More

Less

Picotamide Property

Melting point:: 128-131℃
Boiling point:: 668.1±55.0 °C(Predicted)
Density: 1.246±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 5 mg/ml with warming).
pka: 13.31±0.46(Predicted)
form: White solid.
color: White
Stability:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.

More

Less

Safety

WGK Germany: 2
RTECS: CZ2235500
Toxicity: LD50 i.p. in male mice: 1205 mg/kg (Orzalesi, Selleri, 1976)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P8477
Product name: Picotamide
Packaging: 5mg
Price: $277
Updated: 2024/03/01

Alfa Aesar

Product number: J67232
Product name: Picotamide, 98%
Packaging: 10mg
Price: $144.9
Updated: 2023/01/06

Cayman Chemical

Product number: 21690
Product name: Picotamide
Purity: ≥98%
Packaging: 5mg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 21690
Product name: Picotamide
Purity: ≥98%
Packaging: 10mg
Price: $109
Updated: 2024/03/01

Cayman Chemical

Product number: 21690
Product name: Picotamide
Purity: ≥98%
Packaging: 25mg
Price: $239
Updated: 2024/03/01

More

Less

Picotamide Chemical Properties,Usage,Production

Description

Picotamide is an unique antithrombotic agent which acts by selectively inhibiting thromboxane synthesis and blocking platelet thromboxane receptors without affecting prostaglandin synthesis. It is reported to be useful in the treatment of myocardial infarction, cerebrovascular disorders, pulmonary embolism and atherosclerosis.

Originator

Manetti-Roberts (Beecham (Italy)

Uses

Picotamide is a dual inhibitor of thromboxane A2 and thromboxane A2 synthase. It is used in aptamers for targeting coagulation factor XIII and there used for treatment of thrombosis.

Uses

Keratolytic.

Definition

ChEBI: 4-methoxy-N1,N3-bis(3-pyridinylmethyl)benzene-1,3-dicarboxamide is a member of benzamides.

brand name

Plactidil

References

Modesti, et al. (1989), Competitive inhibition of platelet thromboxane A2 receptor binding by picotamide; Eur. J. Pharmacol.. 169 85 Modesti, et al. (1991), Acute reduction of TxA2 platelet binding sites after in vivo administration of a TxA2 inhibitor; Br. J. Pharmacol.. 31 439 Ratti et al. (1998), Picotamide, an antithromboxane agent. Inhibits the migration and proliferation of arterial myocytes; Eur. J. Pharmacol. 355 77

Picotamide Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Picotamide Suppliers

China 22 Europe 2 France 1 Germany 1 India 2 Switzerland 1 United Kingdom 3 United States 17 Global 49

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7815
Advantage: 57

Shanghai TaoSu Biochemical Technology Co., Ltd.

Tel: 021-33632979
Fax: 021-34692979
Email: info@tsbiochem.com
Country: China
ProdList: 8073
Advantage: 58

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9709
Advantage: 58

Shanghai Vigor Biotechnology Co., Ltd.

Tel: info@vigorchem.cn 1801605789
Fax: QQ：1801605789
Country: China
ProdList: 169
Advantage: 58

Shanghai Yu Ben Biotechnology Co., Ltd.

Tel: 15502154572
Fax: -
Email: yuben012@sina.com
Country: China
ProdList: 505
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: 0551-65418671
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34572
Advantage: 58

Hefei Hirisun Pharmatech Co., Ltd

Tel: +8615056975894
Fax: 86-0551-62678551
Email: shawn@hirisunpharm.com
Country: CHINA
ProdList: 9923
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11289
Advantage: 58

Wuhan penglei Biotechnology Co., Ltd

Tel: 15871464247
Email: 1545569349@QQ.COM
Country: China
ProdList: 707
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44941
Advantage: 58

Jinan Jiuli Biotechnology Co. , Ltd.

Tel: 2717893647 14768611851
Email: 486064515@qq.com
Country: China
ProdList: 966
Advantage: 58

Shanghai Universal Biotech Co.,Ltd

Tel: 18768175414
Email: gaojun@univ-bio.com
Country: China
ProdList: 24998
Advantage: 58

Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.

Tel: +86-027-59232304 15387063101
Email: 2881924050@qq.com
Country: China
ProdList: 9940
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24131
Advantage: 58

Shaanxi Dideu Newmaterial Co., Ltd.

Tel: 029-63373950 15353716720
Email: 1052@dideu.com
Country: China
ProdList: 10011
Advantage: 58

Suzhou Zhixin Biotechnology Co., Ltd.

Tel: 0512-65118909 15162312715
Email: sales@szzxbio.com
Country: China
ProdList: 2999
Advantage: 58

Xianning Shen Lan Biomedical Research and Development Co., Ltd.

Tel: 18171815831
Email: 1341138380@qq.com
Country: China
ProdList: 2780
Advantage: 58

LEAPCHEM CO., LTD.

Tel: +86-852-30606658
Email: market18@leapchem.com
Country: China
ProdList: 43348
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6846
Advantage: 58

HeFei PhotoChem Trading CO.,LTD

Tel: --
Fax: --
Country: China
ProdList: 40
Advantage: 46

Guangzhou WeiBo Chemical Co., Ltd.

Tel: --
Fax: --
Email: weibochem@163.com
Country: China
ProdList: 6187
Advantage: 67

32828-81-2, PicotamideRelated Search:

N-Eicosanoyl Serotonin DO264 Ibrutinib 3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-Thiophenecarboxamide 3-METHYL-4-METHOXYBENZYLAMINE (4-METHOXY-BENZYL)-PYRIDIN-3-YLMETHYL-AMINE ISOPHTHALAMIDE (2-METHOXY-BENZYL)-PYRIDIN-3-YLMETHYL-AMINE 5-Methylsalicylamide 3-carbamyl-(3'-picolyl)-4-methoxy-1-benzamide Picotamide

4-METHOXY-N,N'-BIS(3-PYRIDINYLMETHYL)-1,3-BENZENEDICARBOXAMIDE

PICOTAMIDE

4-methoxy-n,n’-bis(3-pyridylmethyl)-isophthalamid

4-methoxy-n,n’-bis(3-pyridylmethyl)isophthalamide

g137

n,n’-bis(3-picolyl)-4-methoxyisophthalamide

n,n’-bis(3-pyridinylmethyl)-4-methoxy-1,3-benzenedicarboxamide

n,n’-bis(3-pyridinylmethyl)-4-methoxy-3-benzenedicarboxamide

4-methoxy-N,N'-bis(3-pyridylmethyl)isophthaldiamide

-1,3-Benzenedicarboxamide, N,N'-bis(3-pyridinylmethyl)-4-methoxy

Isophthalamide, 4-methoxy-N,N'-bis(3-pyridylmethyl)-

N,N’-Bis(3-Pyridinylmethyl)-4-Me

4-methoxy-1-N,3-N-bis(pyridin-3-ylmethyl)benzene-1,3-dicarboxamide

1,3-Benzenedicarboxamide, 4-methoxy-N1,N3-bis(3-pyridinylmethyl)-

inhibit,Picotamide,Inhibitor,Prostaglandin Receptor,Antiplatelet,Microalbuminuria,Carotid plaques

32828-81-2

C21H20N4O3H2O

C21H20N4O3

Enzymes, Inhibitors, and Substrates

Enzyme Inhibitors

Enzyme Inhibitors by Enzyme

Thromboxane synthase

R to Z

BioChemical

Biochemicals and Reagents