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DULCITOL

Product Name
DULCITOL
CAS No.
6051-87-2
Chemical Name
DULCITOL
Synonyms
BNF;BETA-NF;DULCITE;NSC 136015;MELAMPYRITE;β-Naphthoflavon;5,6-BENZOFLAVONE;B-NAPHTHOFLAVONE;β-Naphthoflavone;BetaNapthoflavone
CBNumber
CB7174209
Molecular Formula
C19H12O2
Formula Weight
272.3
MOL File
6051-87-2.mol
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DULCITOL Property

Melting point:
164-166 °C (lit.)
Boiling point:
275-280 °C (1 mmHg)
Density 
1.1382 (rough estimate)
refractive index 
1.5510 (estimate)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly, Heated)
form 
Crystalline Powder
color 
yellow to tan
BRN 
18991
LogP
5.003 (est)
CAS DataBase Reference
6051-87-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi,C,F
Risk Statements 
22-34-11
Safety Statements 
24/25-45-36/37/39-26-16
WGK Germany 
3
RTECS 
QL6200000
3-10
Hazard Note 
Irritant
HS Code 
29329900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N3633
Product name
β-Naphthoflavone
Purity
≥98%
Packaging
1g
Price
$54.3
Updated
2024/03/01
Sigma-Aldrich
Product number
N3633
Product name
β-Naphthoflavone
Purity
≥98%
Packaging
5g
Price
$151
Updated
2024/03/01
TCI Chemical
Product number
N0518
Product name
beta-Naphthoflavone
Purity
>99.0%(GC)
Packaging
1g
Price
$34
Updated
2024/03/01
TCI Chemical
Product number
N0518
Product name
beta-Naphthoflavone
Purity
>99.0%(GC)
Packaging
5g
Price
$109
Updated
2024/03/01
Alfa Aesar
Product number
A18543
Product name
beta-Naphthoflavone, 98+%
Packaging
1g
Price
$36.65
Updated
2024/03/01
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DULCITOL Chemical Properties,Usage,Production

Chemical Properties

SLIGHTLY BEIGE CRYSTALLINE POWDER

Uses

beta-Naphthoflavone is a Cytochrome P450 enzyme system inducer. It can also be used in biological study of novel dual-color luciferase reporter assay for simultaneous detection of estrogen and aryl hydrocarbon receptor activation.

Definition

ChEBI: An extended flavonoid resulting from the formal fusion of a benzene ring with the f side of flavone.

General Description

β-Naphthoflavone is a polyaromatic hydrocarbon.

Biochem/physiol Actions

β-Naphthoflavone (BNF) is an exogenous ligand for aryl hydrocarbon receptor (AhR) in humans. It is an inducer of phase I detoxification enzymes (CYPs) and phase II enzymes (UDP-GTs) and NAD(P)H-dependent quinone oxyreductase-1(NQO1). It also induces cytochrome P450 (Cyp1a). BNF represses the expression of Duchenne muscular dystrophy gene, dystrophin (Dp)71 by altering the binding of the transcription factors.

DULCITOL Preparation Products And Raw materials

Raw materials

Preparation Products

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DULCITOL Suppliers

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