2-BROMO-6-FLUOROBENZOTHIAZOLE
- Product Name
- 2-BROMO-6-FLUOROBENZOTHIAZOLE
- CAS No.
- 152937-04-7
- Chemical Name
- 2-BROMO-6-FLUOROBENZOTHIAZOLE
- Synonyms
- 2-BROMO-6-FLUOROBENZOTHIAZOLE;2-bromo-6-fluoroobenzothiazole;Benzothiazole, 2-bromo-6-fluoro-;2-bromo-6-fluorobenzo[d]thiazole;2-broMo-6-fluoro-1,3-benzothiazole;2-Bromo-6-fluoroobenzo[d]thiazole, 97%
- CBNumber
- CB7176975
- Molecular Formula
- C7H3BrFNS
- Formula Weight
- 232.07
- MOL File
- 152937-04-7.mol
2-BROMO-6-FLUOROBENZOTHIAZOLE Property
- Boiling point:
- 298.3±32.0 °C(Predicted)
- Density
- 1.832
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -0.39±0.10(Predicted)
- Appearance
- Light yellow to yellow Solid
Safety
- HS Code
- 29342000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H290May be corrosive to metals
H302Harmful if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P337+P313IF eye irritation persists: Get medical advice/attention.
P390Absorb spillage to prevent material damage.
N-Bromosuccinimide Price
- Product number
- B700270
- Product name
- 2-Bromo-6-fluorobenzothiazole
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 072677
- Product name
- 2-Bromo-6-fluorobenzothiazole
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $34
- Updated
- 2021/12/16
- Product number
- 072677
- Product name
- 2-Bromo-6-fluorobenzothiazole
- Purity
- 95+%
- Packaging
- 500mg
- Price
- $52
- Updated
- 2021/12/16
- Product number
- 072677
- Product name
- 2-Bromo-6-fluorobenzothiazole
- Purity
- 95+%
- Packaging
- 1g
- Price
- $79
- Updated
- 2021/12/16
- Product number
- 8561CS
- Product name
- 2-Bromo-6-fluorobenzothiazole
- Packaging
- 5g
- Price
- $350
- Updated
- 2021/12/16
2-BROMO-6-FLUOROBENZOTHIAZOLE Chemical Properties,Usage,Production
Synthesis
348-40-3
7787-70-4
152937-04-7
(Step 1) Synthesis of 2-bromo-6-fluorobenzothiazole: Copper(I) bromide (619 mg, 4.32 mmol) was suspended in acetonitrile (10 mL). To this suspension was added tert-butyl nitrite (640 mg, 5.38 mmol) followed by stirring at 60°C for 5 min. To the reaction mixture was added 2-amino-6-fluorobenzothiazole (605 mg, 3.60 mmol). The resulting mixture was stirred at 60°C for 10 minutes. After completion of the reaction, it was cooled to room temperature and the reaction mixture was diluted with ethyl acetate. The ethyl acetate layer was washed sequentially with 1N HCl and saturated saline and then dried over anhydrous sodium sulfate. The solvent was removed by distillation under reduced pressure to obtain the crude product. The crude product was purified by silica gel column chromatography using n-hexane/ethyl acetate (5:1, v/v) as eluent to afford 2-bromo-6-fluorobenzothiazole (330 mg, 40% yield) as a brown solid. The structure of the product was confirmed by 1H-NMR (CDCl3) δ: 7.19-7.24 (m, 1H), 7.49-7.52 (m, 1H), 7.92-7.96 (m, 1H) and mass spectrometry (ESI) m/z 273.8 ([M + H + MeCN]+).
References
[1] Patent: EP1346982, 2003, A1
[2] Patent: US5371093, 1994, A
2-BROMO-6-FLUOROBENZOTHIAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
2-BROMO-6-FLUOROBENZOTHIAZOLE Suppliers
- Tel
- 021-31261262/ 49 (0)17662837245
- Fax
- (0)21-33250524
- sales@novochemy.com
- Country
- Germany
- ProdList
- 6328
- Advantage
- 58
View Lastest Price from 2-BROMO-6-FLUOROBENZOTHIAZOLE manufacturers
- Product
- 2-BROMO-6-FLUOROBENZOTHIAZOLE 152937-04-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000KG
- Release date
- 2019-12-23