2-Bromo-1,3-benzothiazole
- Product Name
- 2-Bromo-1,3-benzothiazole
- CAS No.
- 2516-40-7
- Chemical Name
- 2-Bromo-1,3-benzothiazole
- Synonyms
- 2-bromobenzo[d]thiazole;2-BROMOBENZOTHIAZOLE;Benzothiazole, 2-bromo-;2-Benzothiazolyl Bromide;2-Bromobenzothiazole >2-BroMobenzothiazole 95%;2-Bromo-1,2-benzothiazole;2-BROMO-1,3-BENZOTHIAZOLE;2-Bromo-1,3-benzothiazole ,97%;Benzothiazole, 2-bromo- (7CI,8CI,9CI)
- CBNumber
- CB2492298
- Molecular Formula
- C7H4BrNS
- Formula Weight
- 214.08
- MOL File
- 2516-40-7.mol
2-Bromo-1,3-benzothiazole Property
- Melting point:
- 39-43 °C
- Boiling point:
- 125°C/7mmHg(lit.)
- Density
- 1.748±0.06 g/cm3(Predicted)
- Flash point:
- >110°(230°F)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- -0.23±0.10(Predicted)
- form
- Crystalline Solid
- color
- Pale yellow
- Water Solubility
- Slightly soluble in water.
- InChI
- InChI=1S/C7H4BrNS/c8-7-9-5-3-1-2-4-6(5)10-7/h1-4H
- InChIKey
- DRLMMVPCYXFPEP-UHFFFAOYSA-N
- SMILES
- S1C2=CC=CC=C2N=C1Br
- CAS DataBase Reference
- 2516-40-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/21/22-36/37/38-36-22
- Safety Statements
- 26-36/37/39
- RIDADR
- 2811
- WGK Germany
- 3
- Hazard Note
- Irritant
- HazardClass
- 6.1
- PackingGroup
- Ⅲ
- HS Code
- 29342000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 678600
- Product name
- 2-Bromobenzothiazole
- Purity
- 95%
- Packaging
- 1g
- Price
- $56.58
- Updated
- 2025/07/31
- Product number
- B3740
- Product name
- 2-Bromobenzothiazole
- Purity
- >95.0%(GC)
- Packaging
- 1g
- Price
- $56
- Updated
- 2025/07/31
- Product number
- B680490
- Product name
- 2-Bromo-1,3-benzothiazole
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- JK238611
- Product name
- 2-Bromo-1,3-benzothiazole
- Purity
- 97%
- Packaging
- 1g
- Price
- $78
- Updated
- 2021/12/16
- Product number
- 7H70-9-Z5
- Product name
- 2-Bromo-1,3-benzothiazole
- Packaging
- 5G
- Price
- $80
- Updated
- 2021/12/16
2-Bromo-1,3-benzothiazole Chemical Properties,Usage,Production
Chemical Properties
White to light brown solid
Uses
2-Bromobenzothiazole, is used as a pharmaceutical intermediate.
Synthesis
95-16-9
2516-40-7
General procedure for the synthesis of 2-bromobenzothiazole from benzothiazole: Benzothiazole (1 mmol, 135.9 mg), carbon tetrabromide (1.1 mmol, 364.8 mg), 5 mL of N,N-dimethylformamide, and sodium tert-butoxide (4.0 mmol, 384.4 mg) were sequentially added to a 10 mL round-bottom flask. The reaction mixture was stirred at room temperature for 3 hours, during which time the progress of the reaction was monitored by thin layer chromatography (TLC). After completion of the reaction, the mixture was poured into water and extracted with dichloromethane. The organic phases were combined and dried with anhydrous sodium sulfate. Subsequently, the dichloromethane was removed by rotary evaporator to obtain the crude product. The crude product was purified by silica gel column chromatography using petroleum ether and ethyl acetate (v/v=30:1) as eluents to give 2-bromobenzothiazole (light yellow oily liquid, 199 mg, 93% yield).
References
[1] Organic and Biomolecular Chemistry, 2018, vol. 16, # 6, p. 886 - 890
[2] Patent: CN107501023, 2017, A. Location in patent: Paragraph 0051; 0052
[3] Organic Letters, 2009, vol. 11, # 2, p. 421 - 423
[4] Journal of Organic Chemistry, 2009, vol. 74, # 21, p. 8309 - 8313
[5] European Journal of Organic Chemistry, 2013, # 9, p. 1644 - 1648
2-Bromo-1,3-benzothiazole Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Bromo-1,3-benzothiazole manufacturers
- Product
- 2-Bromo-1,3-benzothiazole 2516-40-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 5mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-06
- Product
- 2-Bromo-1,3-benzothiazole 2516-40-7
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- customise
- Release date
- 2018-08-09