6-Bromobenzothiazole
- Product Name
- 6-Bromobenzothiazole
- CAS No.
- 53218-26-1
- Chemical Name
- 6-Bromobenzothiazole
- Synonyms
- 6-Bromobenzthiazol;6-BROMO-BENZOTHIAZOLE;BENZOTHIAZOLE, 6-BROMO-;6-Bromobenzothiazole,97%;6-BROMO-BENZO[D]THIAZOLE;6-BROMO-1,3-BENZOTHIAZOLE;Benzothiazole, 6-bromo- (9CI);6-Bromo-1,3-benzothiazole 97%;6-Bromo-1,3-benzothiazole ,97%
- CBNumber
- CB9280191
- Molecular Formula
- C7H4BrNS
- Formula Weight
- 214.08
- MOL File
- 53218-26-1.mol
6-Bromobenzothiazole Property
- Melting point:
- 52-54℃
- Boiling point:
- 143 °C(Press: 12 Torr)
- Density
- 1.748±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- form
- Solid
- pka
- 0.21±0.10(Predicted)
- color
- Off-white to yellow
- CAS DataBase Reference
- 53218-26-1(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26-37/39
- RIDADR
- 2811
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H301Toxic if swalloed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P321Specific treatment (see … on this label).
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- B6336
- Product name
- 6-Bromo-1,3-benzothiazole
- Purity
- min. 98.0 %
- Packaging
- 5G
- Price
- $166
- Updated
- 2025/07/31
- Product number
- B680623
- Product name
- 6-Bromobenzothiazole
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- B680623
- Product name
- 6-Bromobenzothiazole
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- HCH0025057
- Product name
- 6-BROMO-1,3-BENZOTHIAZOLE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $159.6
- Updated
- 2021/12/16
- Product number
- 7H70-9-Y1
- Product name
- 6-Bromo-1,3-benzothiazole
- Packaging
- 1g
- Price
- $128
- Updated
- 2021/12/16
6-Bromobenzothiazole Chemical Properties,Usage,Production
Chemical Properties
Off-white powder
Uses
6-Bromobenzothiazole is a benzothiazole analogue. It can be used as a pharmaceutical intermediate or a raw material for the preparation of other aza-aromatic compounds.
Synthesis
533-30-2
53218-26-1
The general procedure for the synthesis of 6-bromobenzothiazole from 6-aminobenzothiazole was as follows: aqueous (1.0 mL) solution of sodium nitrite (0.147 g, 2.1 mmol) was slowly added dropwise to a mixture of 6-aminobenzothiazole (0.30 g, 2.0 mmol) suspended in a 48% aqueous hydrobromic acid solution (3 mL) at 0 °C. After the dropwise addition was completed, the reaction mixture was stirred at room temperature for 30 minutes. Subsequently, the resulting solution was slowly added to a hydrochloric acid solution (concentration not specified, 5 mL) of copper (I) bromide (0.435 g, 3.0 mmol) at 0 °C. After addition, the reaction system was warmed to 60 °C and stirred for 1.5 hours. Upon completion of the reaction, the reaction mixture was cooled, alkalized with excess ammonia and extracted with ether. The organic phases were combined, washed sequentially with water and saturated saline, dried anhydrous and concentrated. Purification by Combiflash fast chromatography afforded 6-bromobenzothiazole (0.26 g). This product was subsequently converted to the target compound using a similar procedure as in Example 1 , with mass spectrometry (ESI) detection showing (M + H)+ = 413.1.
References
[1] Organic Letters, 2007, vol. 9, # 18, p. 3623 - 3625
[2] Patent: WO2004/50659, 2004, A1. Location in patent: Page 49-50
[3] Patent: WO2014/151147, 2014, A1. Location in patent: Paragraph 00154
[4] Patent: US2014/357651, 2014, A1. Location in patent: Paragraph 0498
[5] Patent: US9174994, 2015, B2. Location in patent: Page/Page column 126
6-Bromobenzothiazole Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-Bromobenzothiazole manufacturers
- Product
- 6-Bromobenzothiazole 53218-26-1
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2025-06-29
- Product
- 6-BROMO-1,3-BENZOTHIAZOLE 53218-26-1
- Price
- US $8.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10tons
- Release date
- 2018-12-25