5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE

Product Name: 5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE
CAS No.: 52157-82-1
Chemical Name: 5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE
Synonyms: RU23686;RU 23686;RU-23686;RU 23686 (free base);5-Methoxy-3-(4-piperidinyl)indole;4-(5-Methoxy-3-indolyl)piperidine;5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE;5-Methoxy-3-(4-piperidinyl)-1H-indole;1H-Indole, 5-methoxy-3-(4-piperidinyl)-;4-(5-methoxy-[1H]-indol-3-yl)-piperidine
CBNumber: CB7190636
Molecular Formula: C14H18N2O
Formula Weight: 230.31
MOL File: 52157-82-1.mol

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5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE Property

Melting point:: 152-153℃
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: M266793
Product name: 5-Methoxy-3-piperidin-4-yl-1H-indole
Packaging: 25mg
Price: $45
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0121674
Product name: 5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE
Purity: 95.00%
Packaging: 1G
Price: $983.52
Updated: 2021/12/16

AK Scientific

Product number: 7327AB
Product name: 5-Methoxy-3-piperidin-4-yl-1H-indole
Packaging: 5g
Price: $1467
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0121674
Product name: 5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE
Purity: 95.00%
Packaging: 2.5G
Price: $1473.14
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0121674
Product name: 5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE
Purity: 95.00%
Packaging: 5G
Price: $1928.08
Updated: 2021/12/16

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5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE Chemical Properties,Usage,Production

Uses

RU 23686 free base is a piperidinylindole derivative. RU 23686 free base can be used to investigate the extent to which different neurotransmitters by the interaction with pharmacological agents[1].

Synthesis

66611-26-5

52157-82-1

General procedure for the synthesis of 5-methoxy-3-piperidin-4-yl-1H-indole from 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole: Intermediate 36 (47.0 g, 0.21 mol) was dissolved in ethanol (500 mL) and 10% Pd/C catalyst (4 g) was added. The hydrogenation reaction was carried out at atmospheric pressure for 24 hours. After completion of the reaction, the mixture was filtered through diatomaceous earth and the filtrate was concentrated by evaporation to give 5-methoxy-3-piperidin-4-yl-1H-indole (45.54 g, 0.2 mol) as an orange solid in 96% yield. The product was characterized by 1H NMR (CDCl3, 300 MHz): δ 7.4 (d, 1H), 7.3 (bd, 1H), 7.1 (s, 1H), 7.0 (dd, 1H), 4.0 (s, 3H), 3.4 (dd, 2H), 2.9-3.0 (m, 3H), 2.2 (m, 2H), 1.9 (m, 2H).

References

[1] Boissier JR, et, al. Pharmacological interactions with circling behaviour induced by the piperidinyl indole derivative RU 23686. Psychopharmacology (Berl). 1977 Nov 24;55(1):53-60. DOI:10.1007/BF00432817

5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE manufacturers

Career Henan Chemical Co

Product: 5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE 52157-82-1
Price: US $5.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2020-01-12

52157-82-1, 5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLERelated Search:

6-(trifluoromethyl)-5-methoxyindoline 6-(trifluoromethyl)-5-methoxy-1H-indole 5-METHOXY-3-(PIPERIDIN-4-YL)-1H-INDOLE HYDROCHLORIDE tert-Butyl 4-(5-methoxy-1H-indol-3-yl)-1-piperidinecarboxylate 5-METHOXY-3-(1-METHYL-4-PIPERIDINYL)INDOLE 3-Piperidin-4-yl-1H-indole 5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE

4-(5-methoxy-[1H]-indol-3-yl)-piperidine

5-Methoxy-3-(4-piperidinyl)-1H-indole

4-(5-Methoxy-3-indolyl)piperidine

5-Methoxy-3-(4-piperidinyl)indole

5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE

1H-Indole, 5-methoxy-3-(4-piperidinyl)-

RU 23686

RU23686

RU-23686

RU 23686 (free base)

52157-82-1