5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE
- Product Name
- 5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE
- CAS No.
- 52157-82-1
- Chemical Name
- 5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE
- Synonyms
- RU23686;RU 23686;RU-23686;RU 23686 (free base);5-Methoxy-3-(4-piperidinyl)indole;4-(5-Methoxy-3-indolyl)piperidine;5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE;5-Methoxy-3-(4-piperidinyl)-1H-indole;1H-Indole, 5-methoxy-3-(4-piperidinyl)-;4-(5-methoxy-[1H]-indol-3-yl)-piperidine
- CBNumber
- CB7190636
- Molecular Formula
- C14H18N2O
- Formula Weight
- 230.31
- MOL File
- 52157-82-1.mol
5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE Property
- Melting point:
- 152-153℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M266793
- Product name
- 5-Methoxy-3-piperidin-4-yl-1H-indole
- Packaging
- 25mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- CHM0121674
- Product name
- 5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $983.52
- Updated
- 2021/12/16
- Product number
- 7327AB
- Product name
- 5-Methoxy-3-piperidin-4-yl-1H-indole
- Packaging
- 5g
- Price
- $1467
- Updated
- 2021/12/16
- Product number
- CHM0121674
- Product name
- 5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $1473.14
- Updated
- 2021/12/16
- Product number
- CHM0121674
- Product name
- 5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1928.08
- Updated
- 2021/12/16
5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE Chemical Properties,Usage,Production
Uses
RU 23686 free base is a piperidinylindole derivative. RU 23686 free base can be used to investigate the extent to which different neurotransmitters by the interaction with pharmacological agents[1].
Synthesis
66611-26-5
52157-82-1
General procedure for the synthesis of 5-methoxy-3-piperidin-4-yl-1H-indole from 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole: Intermediate 36 (47.0 g, 0.21 mol) was dissolved in ethanol (500 mL) and 10% Pd/C catalyst (4 g) was added. The hydrogenation reaction was carried out at atmospheric pressure for 24 hours. After completion of the reaction, the mixture was filtered through diatomaceous earth and the filtrate was concentrated by evaporation to give 5-methoxy-3-piperidin-4-yl-1H-indole (45.54 g, 0.2 mol) as an orange solid in 96% yield. The product was characterized by 1H NMR (CDCl3, 300 MHz): δ 7.4 (d, 1H), 7.3 (bd, 1H), 7.1 (s, 1H), 7.0 (dd, 1H), 4.0 (s, 3H), 3.4 (dd, 2H), 2.9-3.0 (m, 3H), 2.2 (m, 2H), 1.9 (m, 2H).
References
[1] Boissier JR, et, al. Pharmacological interactions with circling behaviour induced by the piperidinyl indole derivative RU 23686. Psychopharmacology (Berl). 1977 Nov 24;55(1):53-60. DOI:10.1007/BF00432817
5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE Preparation Products And Raw materials
Raw materials
Preparation Products
5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE Suppliers
- Tel
- --
- Fax
- --
- contact@achemica.com
- Country
- Switzerland
- ProdList
- 6155
- Advantage
- 50
View Lastest Price from 5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE manufacturers
- Product
- 5-METHOXY-3-PIPERIDIN-4-YL-1H-INDOLE 52157-82-1
- Price
- US $5.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2020-01-12