D-ASPARTIC ACID-BETA-METHYL ESTER
- Product Name
- D-ASPARTIC ACID-BETA-METHYL ESTER
- CAS No.
- 21394-81-0
- Chemical Name
- D-ASPARTIC ACID-BETA-METHYL ESTER
- Synonyms
- D-Asp(Ome).HCl;D-Asp(OMe)-OH·HCl;H-D-Aspartic acid-;Asparagine Impurity 24;D-ASPARTICACID-β-METHYLESTER;β-Methyl (2R)-aspartate ester;D-Aspartic acid-β-methyl ester;H-D-Aspartic acid-β-methyl ester;D-ASPARTIC ACID-BETA-METHYL ESTER;H-D-ASPARTIC ACID-SS-METHYL ESTER
- CBNumber
- CB7191668
- Molecular Formula
- C5H9NO4
- Formula Weight
- 147.13
- MOL File
- 21394-81-0.mol
D-ASPARTIC ACID-BETA-METHYL ESTER Property
- Melting point:
- 188-190 °C
- Boiling point:
- 301.7±37.0 °C(Predicted)
- Density
- 1.299
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 2.16±0.23(Predicted)
- Appearance
- White to off-white Solid
- optical activity
- 23.2°(C=1.00g/100ml MEOH)
N-Bromosuccinimide Price
- Product number
- 05942
- Product name
- D-Asparticacidβ-methylesterhydrochloride,99%(Assay)
- Purity
- 99%(Assay)
- Packaging
- 1G
- Price
- $72.8
- Updated
- 2021/12/16
- Product number
- FA48674
- Product name
- D-Aspartic acid beta-methyl ester hydrochloride
- Packaging
- 500mg
- Price
- $95
- Updated
- 2021/12/16
- Product number
- FA48674
- Product name
- D-Aspartic acid beta-methyl ester hydrochloride
- Packaging
- 1g
- Price
- $150
- Updated
- 2021/12/16
- Product number
- AAA0003800
- Product name
- D-ASPARTIC ACID-BETA-METHYL ESTER
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $179.55
- Updated
- 2021/12/16
- Product number
- V1600
- Product name
- D-Asparticacid-beta-methylester
- Packaging
- 25g
- Price
- $235
- Updated
- 2021/12/16
D-ASPARTIC ACID-BETA-METHYL ESTER Chemical Properties,Usage,Production
Definition
ChEBI: Methyl gamma-D-aspartate is a dicarboxylic acid monoester obtained by condensation of the side-chain carboxy group of D-aspartic acid with methanol. It has a role as a bacterial metabolite. It is a D-aspartic acid derivative and a dicarboxylic acid monoester.
Synthesis
67-56-1
1783-96-6
21394-81-0
At 0 °C, 73.7 mL of acetyl chloride (1.4 eq.) was slowly added dropwise to 250 mL of methanol. Maintaining 0 °C, the mixture was added dropwise to a 250 mL methanol suspension containing 100 g (751 mmol) of (R)-2-aminosuccinic acid. The reaction mixture was stirred at 0 °C for 3 h before gradually warming to room temperature and continuing to stir overnight. Five identical reaction vials were set up in parallel for the same operation. The mixtures from all six reaction flasks were combined and concentrated under reduced pressure. The concentrated residue was treated with methyl tert-butyl ether (MTBE) and the resulting precipitate was filtered and dried under reduced pressure to give (R)-2-amino-4-methoxy-4-oxobutanoic acid (600 g, 90% yield) as a white solid. The product was characterized by 1H NMR (400 MHz, deuterium oxide): δ 4.33 (t, J = 5.5 Hz, 1H), 3.81 (s, 1H), 3.72 (s, 3H), 3.10 (d, J = 4.9 Hz, 2H).
References
[1] Patent: WO2017/89458, 2017, A1. Location in patent: Page/Page column 72
[2] Gazzetta Chimica Italiana, 1986, vol. 116, # 10, p. 607 - 608
[3] Patent: CN106518701, 2017, A. Location in patent: Paragraph 0021-0022
D-ASPARTIC ACID-BETA-METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from D-ASPARTIC ACID-BETA-METHYL ESTER manufacturers
- Product
- D-Asp(Ome).HCl 21394-81-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T+
- Release date
- 2024-03-21