2,6-BIS(BROMOMETHYL)PYRIDINE

Product Name: 2,6-BIS(BROMOMETHYL)PYRIDINE
CAS No.: 7703-74-4
Chemical Name: 2,6-BIS(BROMOMETHYL)PYRIDINE
Synonyms: SKL650;2,6-Bis(bromoethyl)pyridine;2,6-Di(bromomethyl)pyridine;2,6-BIS(BROMOMETHYL)PYRIDINE;Pyridine, 2,6-bis(bromomethyl)-;2,6-Bis(bromomethyl)pyridine >2,6-Bis(broMoMethyl)pyridine 98%;alpha,alpha'-Dibromo-2,6-lutidine;2,6-BIS(BROMOMETHYL)PYRIDINE ISO 9001：2015 REACH
CBNumber: CB7192135
Molecular Formula: C7H7Br2N
Formula Weight: 264.95
MOL File: 7703-74-4.mol

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2,6-BIS(BROMOMETHYL)PYRIDINE Property

Melting point:: 85-87 °C(lit.)
Boiling point:: 275.6±30.0 °C(Predicted)
Density: 1.870±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: powder to crystaline
pka: 1.65±0.24(Predicted)
color: White to Almost white
InChI: InChI=1S/C7H7Br2N/c8-4-6-2-1-3-7(5-9)10-6/h1-3H,4-5H2
InChIKey: QUTSYCOAZVHGGT-UHFFFAOYSA-N
SMILES: C1(CBr)=NC(CBr)=CC=C1

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Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38
Safety Statements: 26-36/37/39
RIDADR: UN 3335
WGK Germany: 3
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 405426
Product name: 2,6-Bis(bromomethyl)pyridine
Purity: 98%
Packaging: 1g
Price: $55.8
Updated: 2025/07/31

Sigma-Aldrich

Product number: 405426
Product name: 2,6-Bis(bromomethyl)pyridine
Purity: 98%
Packaging: 5g
Price: $206.08
Updated: 2025/07/31

TCI Chemical

Product number: B1936
Product name: 2,6-Bis(bromomethyl)pyridine
Purity: >99.0%(GC)(T)
Packaging: 1g
Price: $65
Updated: 2025/07/31

TCI Chemical

Product number: B1936
Product name: 2,6-Bis(bromomethyl)pyridine
Purity: >99.0%(GC)(T)
Packaging: 5g
Price: $228
Updated: 2025/07/31

Biosynth Carbosynth

Product number: FB74901
Product name: 2,6-Bis(bromomethyl)pyridine
Packaging: 250mg
Price: $60
Updated: 2021/12/16

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2,6-BIS(BROMOMETHYL)PYRIDINE Chemical Properties,Usage,Production

Uses

2,6-Bis(bromomethyl)pyridine may be used in the preparation of the following:

a new pyridine-pyrazole derivative, 2,6-bis(3,5-diphenylpyrazol-1-ylmethyl)pyridine
a large macrocyclic ligand, N(1),N(7)-pyridine-2,6-dimethyl-N(2),N(6)-bis(6-(3-(1H-benzo[d]imidazol-1-yl)propanamido)pyridin-2-yl)pyridine-2,6-dicarboxamide dibromide
small-ring, potentially tridentate Se(2)N(pyridyl)-donor macrocycles

General Description

Crystal of 2,6-bis(bromomethyl)pyridine has the molecules related by a c-glide-plane operation. Molecules are arranged into stacks along the c axis. It participates in the synthesis of dicationic imidazolium-linked cyclophane.

Synthesis

1195-59-1

7703-74-4

Example 15 Synthesis of 2,6-bis(bromomethyl)pyridine. To pyridine-2,6-dimethanol (2 g, 14 mmol) was slowly added 60% hydrobromic acid (15 mL). The reaction mixture was heated to reflux at 125 °C for 6 h and subsequently cooled to room temperature. The reaction residue was dissolved in water (50 mL) to form a yellow solution. To this solution saturated sodium bicarbonate solution was added dropwise until the pH reached 8. The resulting aqueous solution was extracted with dichloromethane (4 x 50 mL) and the organic layers were combined and dried over anhydrous sodium sulfate. The solvent was removed by rotary evaporation and the resulting crude product was purified by fast column chromatography (ethyl acetate/hexane, 1:9 to 1:4 gradient elution) to afford 2,6-bis(bromomethyl)pyridine (3.5 g, 96% yield) as a white solid. The structure of the product was analyzed by 1H NMR (500 MHz, CDCl3) δ 4.53 (s, 4H), 7.36-7.38 (d, J = 8.0 Hz, 2H), 7.68-7.71 (dd, J = 7.5,8.0 Hz, 1H); 13C NMR (125 MHz, CDCl3) δ 33.8,123.1,138.4, 157.0; LC-TOF (M + H+) calculated value C7H8Br2N 263.90235, measured value 263.90193 confirmed.

References

[1] Patent: US2010/203613, 2010, A1. Location in patent: Page/Page column 10
[2] Journal of Medicinal Chemistry, 2011, vol. 54, # 7, p. 2039 - 2048
[3] Organic and Biomolecular Chemistry, 2014, vol. 12, # 47, p. 9601 - 9620
[4] European Journal of Organic Chemistry, 1999, # 9, p. 2373 - 2381
[5] European Journal of Organic Chemistry, 2017, vol. 2017, # 35, p. 5252 - 5261

2,6-BIS(BROMOMETHYL)PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,6-BIS(BROMOMETHYL)PYRIDINE Suppliers

Americas 1 Belgium 1 China 113 Europe 1 Germany 3 India 7 Japan 2 Switzerland 1 United Kingdom 5 United States 26 Global 160

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View Lastest Price from 2,6-BIS(BROMOMETHYL)PYRIDINE manufacturers

Dideu Industries Group Limited

Product: 2,6-BIS(BROMOMETHYL)PYRIDINE 7703-74-4
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-08-27

Career Henan Chemical Co

Product: 2,6-BIS(BROMOMETHYL)PYRIDINE 7703-74-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2019-07-02

7703-74-4, 2,6-BIS(BROMOMETHYL)PYRIDINERelated Search:

4-Bromo-2,6-bis(bromomethyl)pyridine 2-(Bromomethyl)pyridine hydrobromide 2-BROMOMETHYL-6-METHYL-PYRIDINE HYDROBROMIDE 2,6-BIS(BROMOMETHYL)PYRIDINE 2-(Bromomethyl)-6-methylpyridine

2,6-Bis(broMoMethyl)pyridine 98%

2,6-Di(bromomethyl)pyridine

alpha,alpha'-Dibromo-2,6-lutidine

2,6-BIS(BROMOMETHYL)PYRIDINE

2,6-Bis(bromomethyl)pyridine &gt

Pyridine, 2,6-bis(bromomethyl)-

2,6-BIS(BROMOMETHYL)PYRIDINE ISO 9001：2015 REACH

SKL650

2,6-Bis(bromoethyl)pyridine

7703-74-4

Pyridines

Halogenated Heterocycles

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C7 and C8Heterocyclic Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

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Building Blocks

C7 to C18

C7 to C8

Chemical Synthesis

Halogenated Heterocycles

Heterocyclic Building Blocks