1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE

Product Name: 1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE
CAS No.: 85375-15-1
Chemical Name: 1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE
Synonyms: skf-89976a;SKF89976AHCl;SKF 89976A HYDROCHLORIDE;l-SKF89976A hydrochloride;d,l-SKF89976A hydrochloride;1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE;1-(4,4-Diphenylbut-3-en-1-yl)piperidine-3-carboxylic acid hydrochloride;1-(4,4-Diphenyl-3-buten-1-yl)-3-piperidinecarboxylic acid hydrochloride;Gamma-aminobutyric acid Receptor,γ-Aminobutyric acid Receptor,d,l-SKF89976A,GABA Receptor,SKF89976A,inhibit,SKF89976A hydrochloride,Inhibitor,SKF-89976A hydrochloride
CBNumber: CB7194179
Molecular Formula: C22H26ClNO2
Formula Weight: 371.9
MOL File: 85375-15-1.mol

More

Less

1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE Property

storage temp.: Inert atmosphere,2-8°C
solubility: DMSO: 20 mg/mL, soluble
form: solid
color: white

More

Less

Safety

WGK Germany: 3
RTECS: TM6241000

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S9066
Product name: SKF-89976A
Purity: >98% (HPLC), solid
Packaging: 10mg
Price: $143
Updated: 2022/05/15

Tocris

Product number: 1081
Product name: SKF89976Ahydrochloride
Purity: ≥99%(HPLC)
Packaging: 10
Price: $159
Updated: 2021/12/16

Tocris

Product number: 1081
Product name: SKF89976Ahydrochloride
Purity: ≥99%(HPLC)
Packaging: 50
Price: $658
Updated: 2021/12/16

TRC

Product number: S550003
Product name: SKF-89976A
Packaging: 25mg
Price: $180
Updated: 2021/12/16

ChemScene

Product number: CS-6040
Product name: SKF89976Ahydrochloride
Purity: 99.33%
Packaging: 50mg
Price: $420
Updated: 2021/12/16

More

Less

1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

SKF-89976A is a GABA transporters (GATs) type 1 inhibitor.

Biological Activity

A potent GABA uptake inhibitor, selective for GAT-1 (IC 50 values are 0.13, 550, 944 and 7210 μ M for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). Inhibits transport current competitively (K i = 7 μ M) and transmitter-gated current non-competitively (K i = 0.03 nM). Able to pass the blood-brain barrier after systemic administration and is active in vivo .

storage

+4°C (desiccate)

1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE Suppliers

China 63 Germany 2 Switzerland 1 United Kingdom 3 United States 13 Global 82

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Ascent Scientific

Tel: 4401179829988
Fax: 4402030 700 369
Email: customerservice@ascentscientific.co.uk
Country: United Kingdom
ProdList: 279
Advantage: 60

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14055
Advantage: 65

NCE Biomedical Co.,Ltd.

Tel: 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Fax: +86-27-87599188
Country: China
ProdList: 1493
Advantage: 55

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

Credit Asia Chemical Co., Ltd.

Tel: +86 (21) 61124340
Fax: +86 (21) 6129-4103
Country: China
ProdList: 9756
Advantage: 58

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4512
Advantage: 55

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9248
Advantage: 55

CHMA Chemical Technology (Shanghai) Co., Ltd

Tel: 021-61556450 15800904410
Fax: 021-61556450
Country: China
ProdList: 2832
Advantage: 58

85375-15-1, 1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDERelated Search:

3-Methyl-1-butene 1-METHYLPIPERIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE 1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE

SKF 89976A HYDROCHLORIDE

1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE

SKF89976AHCl

skf-89976a

1-(4,4-Diphenyl-3-buten-1-yl)-3-piperidinecarboxylic acid hydrochloride

1-(4,4-Diphenylbut-3-en-1-yl)piperidine-3-carboxylic acid hydrochloride

l-SKF89976A hydrochloride

d,l-SKF89976A hydrochloride

Gamma-aminobutyric acid Receptor,γ-Aminobutyric acid Receptor,d,l-SKF89976A,GABA Receptor,SKF89976A,inhibit,SKF89976A hydrochloride,Inhibitor,SKF-89976A hydrochloride

85375-15-1

C22H25NO2HCl

Ion Channels

Ligand-Gated Ion Channels

GABA and Glycine Receptor Modulators

Cell Biology

Cell Signaling and Neuroscience

BioChemical

GABA/Glycine receptor

GABA