ChemicalBook > CAS DataBase List > 1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE

1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE

Product Name
1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE
CAS No.
85375-15-1
Chemical Name
1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE
Synonyms
skf-89976a;SKF89976AHCl;SKF 89976A HYDROCHLORIDE;l-SKF89976A hydrochloride;d,l-SKF89976A hydrochloride;1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE;1-(4,4-Diphenylbut-3-en-1-yl)piperidine-3-carboxylic acid hydrochloride;1-(4,4-Diphenyl-3-buten-1-yl)-3-piperidinecarboxylic acid hydrochloride;Gamma-aminobutyric acid Receptor,γ-Aminobutyric acid Receptor,d,l-SKF89976A,GABA Receptor,SKF89976A,inhibit,SKF89976A hydrochloride,Inhibitor,SKF-89976A hydrochloride
CBNumber
CB7194179
Molecular Formula
C22H26ClNO2
Formula Weight
371.9
MOL File
85375-15-1.mol
More
Less

1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE Property

storage temp. 
Inert atmosphere,2-8°C
solubility 
DMSO: 20 mg/mL, soluble
form 
solid
color 
white
More
Less

Safety

WGK Germany 
3
RTECS 
TM6241000
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S9066
Product name
SKF-89976A
Purity
>98% (HPLC), solid
Packaging
10mg
Price
$143
Updated
2022/05/15
Tocris
Product number
1081
Product name
SKF89976Ahydrochloride
Purity
≥99%(HPLC)
Packaging
10
Price
$159
Updated
2021/12/16
Tocris
Product number
1081
Product name
SKF89976Ahydrochloride
Purity
≥99%(HPLC)
Packaging
50
Price
$658
Updated
2021/12/16
TRC
Product number
S550003
Product name
SKF-89976A
Packaging
25mg
Price
$180
Updated
2021/12/16
ChemScene
Product number
CS-6040
Product name
SKF89976Ahydrochloride
Purity
99.33%
Packaging
5mg
Price
$72
Updated
2021/12/16
More
Less

1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

SKF-89976A is a GABA transporters (GATs) type 1 inhibitor.

Biological Activity

A potent GABA uptake inhibitor, selective for GAT-1 (IC 50 values are 0.13, 550, 944 and 7210 μ M for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). Inhibits transport current competitively (K i = 7 μ M) and transmitter-gated current non-competitively (K i = 0.03 nM). Able to pass the blood-brain barrier after systemic administration and is active in vivo .

storage

+4°C (desiccate)

1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE Suppliers

China 63 Germany 2 Switzerland 1 United Kingdom 3 United States 13 Global 82
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
NCE Biomedical Co.,Ltd.
Tel
4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Fax
+86-27-87599188
Country
China
ProdList
1493
Advantage
55
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9756
Advantage
58
LETOPHARM LIMITED
Tel
+86-21-5821 5861
Fax
+86-21-5106 2861
Email
sales@letopharm.com
Country
China
ProdList
2384
Advantage
58
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4512
Advantage
55
SPIRO PHARMA
Tel
Fax
-
Email
eric_feng1954@126.com
Country
China
ProdList
9248
Advantage
55
CHMA Chemical Technology (Shanghai) Co., Ltd
Tel
021-61556450 15800904410
Fax
021-61556450
Country
China
ProdList
2832
Advantage
58
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ：65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
7268
Advantage
58
Shanghai SuperLan Chemcial Technique Centre
Tel
021-2022843681 15618226720
Fax
+86-21-51601218
Email
lucy@atkchemical.com
Country
China
ProdList
10285
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29785
Advantage
68
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
MQ (shanghai) Pharmaceuticals Co., Ltd.
Tel
13761635123
Fax
1014988033@qq
Email
1014988033@qq.com
Country
China
ProdList
4983
Advantage
55
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28806
Advantage
58
Aikon International Limited
Tel
025-66113011 13155353615
Fax
(7)02557626880
Email
qzhang@aikonchem.com
Country
China
ProdList
15394
Advantage
58
Fujian boshi pharmaceutical technology co. LTD
Tel
0595-22008920; 18120708884
Email
393612455@qq.com
Country
China
ProdList
255
Advantage
58
Hefei Hirisun Pharmatech Co., Ltd
Tel
+8615056975894
Fax
86-0551-62678551
Email
shawn@hirisunpharm.com
Country
CHINA
ProdList
9911
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30240
Advantage
58
DC Chemicals
Tel
021-58447131 13564518121
Email
sales@dcchemicals.com
Country
China
ProdList
9409
Advantage
58
Changzhou Chenhong Biotechnology Co., Ltd.
Tel
0519-85788828 13775037613
Email
sales@chemrenpharm.com
Country
China
ProdList
3600
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11217
Advantage
58
Absin Bioscience Inc.
Tel
021-38015121 15000105423
Email
wulan@absin.cn
Country
China
ProdList
24731
Advantage
58
Shanghai hongqu biomedical technology co. LTD
Tel
88888888888
Email
hongquchem@qq.com
Country
China
ProdList
5132
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
Abmole Bioscience Inc.
Tel
021-50967598 02150967598
Email
sales@abmole.cn
Country
China
ProdList
4494
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29774
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
62075
Advantage
58
Kaifeng Mingren Pharmaceutical Co.,LTD
Tel
0371-65741762
Fax
QQ：2860768577
Email
sales@hasunny.com
Country
China
ProdList
2380
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24647
Advantage
58
Suzhou Zhixin Biotechnology Co., Ltd.
Tel
0512-65118909 15162312715
Email
sales@szzxbio.com
Country
China
ProdList
2990
Advantage
58
Wuhan Jingkangen Biomedical Technology Co., Ltd
Tel
13720134139 13720134139
Email
orders@jknbiochem.com
Country
China
ProdList
5797
Advantage
58
https://hanhongsci.com/
Tel
021-54306202 18917919676
Email
info@hanhongsci.com
Country
China
ProdList
29977
Advantage
58
Nanjing Bic Biotechnology Co., Ltd
Tel
025-58906079 17352406906
Email
sales@bicbiotech.com
Country
China
ProdList
7679
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 15850508050
Fax
025-85563444
Email
cindy.huang@synzest.com
Country
China
ProdList
12005
Advantage
58
RD International Technology Co., Limited
Tel
18024082417
Email
market@ubiochem.com
Country
China
ProdList
9272
Advantage
58
Olix (Shanghai) Pharmaceutical Technology Co., Ltd
Tel
17316404525
Email
209533805@qq.com
Country
China
ProdList
9763
Advantage
58
xinguokeji
Tel
13120711461
Email
363372932@qq.com
Country
China
ProdList
496
Advantage
58
Anhui Leyong Biotechnology Co.,Ltd
Tel
15055708011
Email
2093564781@qq.com
Country
China
ProdList
342
Advantage
58
ATK CHEMICAL COMPANY LIMITED
Tel
+undefined-21-51877795
Fax
+86 21 5161 9052/ 5187 7796
Email
ivan@atkchemical.com
Country
China
ProdList
32957
Advantage
60
Wuhan Jingkang en Biomedical Technology Co., Ltd
Tel
+8613720134139
Email
orders@jknbiochem.com
Country
China
ProdList
5221
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6650
Advantage
58
Beijing Dongge Boye Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1861586486@qq.com
Country
CHINA
ProdList
6648
Advantage
58
Shanghai Qiming Biological Technology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6502
Advantage
58
Beijing Taize Jiaye Technology Development Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6050
Advantage
58
Shanghai Haoyang Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
596799915@QQ.COM
Country
CHINA
ProdList
2905
Advantage
58
Xiamen Huijia Biological Technology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6973
Advantage
58
Shanghai Jingke Chemical Technology Co., Ltd.
Tel
--
Fax
--
Email
jingkehuaxue@163.com
Country
CHINA
ProdList
6972
Advantage
58
Shanghai Yuda Industrial Co., Ltd.
Tel
--
Fax
--
Email
lucy@runwelltac.com
Country
CHINA
ProdList
6105
Advantage
58
Wuhan Boot Biotechnology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6829
Advantage
58

85375-15-1, 1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDERelated Search:

3-Methyl-1-butene 1-METHYLPIPERIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE 1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE

  • SKF 89976A HYDROCHLORIDE
  • 1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE
  • SKF89976AHCl
  • skf-89976a
  • 1-(4,4-Diphenyl-3-buten-1-yl)-3-piperidinecarboxylic acid hydrochloride
  • 1-(4,4-Diphenylbut-3-en-1-yl)piperidine-3-carboxylic acid hydrochloride
  • l-SKF89976A hydrochloride
  • d,l-SKF89976A hydrochloride
  • Gamma-aminobutyric acid Receptor,γ-Aminobutyric acid Receptor,d,l-SKF89976A,GABA Receptor,SKF89976A,inhibit,SKF89976A hydrochloride,Inhibitor,SKF-89976A hydrochloride
  • 85375-15-1
  • C22H25NO2HCl
  • Ion Channels
  • Ligand-Gated Ion Channels
  • GABA and Glycine Receptor Modulators
  • Cell Biology
  • Cell Signaling and Neuroscience
  • BioChemical
  • GABA/Glycine receptor
  • GABA