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GMDP

Product Name
GMDP
CAS No.
70280-03-4
Chemical Name
GMDP
Synonyms
GMDP;syl)muramoyl)-l-alanyl-;glucosaminylmuramyldipeptide;4-(2-ACETAMIDO-2-DEOXY-B-D- &;4-(2-acetamido-2-deoxy-B-D-*glucopyranosyl)-N-ace;d-glcnac-β-(1→4)-n-acetylmuramyl-l-ala-d-isoglutamine;D-GLCNAC-BETA-(1->4)-N-ACETYLMURAMYL-L-ALA-D-ISOGLUTAMINE;N-Acetyl-D-glucosaminyl-(b1,4)-N-acetylmuramyl-L-alanyl-D-io;n-acetylglucosaminyl-n-acetylmuramyl-l-alanyl-d-isoglutamine;n-acetyl-beta-glucosaminyl-n-acetylmuramyl-alanylisoglutamine
CBNumber
CB7201998
Molecular Formula
C27H45N5O16
Formula Weight
695.67
MOL File
70280-03-4.mol
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GMDP Property

storage temp. 
−20°C
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22
Safety Statements 
36/37
WGK Germany 
3
RTECS 
MA2275230
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A187085
Product name
N-​Acetyl-​β-​D-​glucosaminyl-​N-​acetylmuramyl-​L-​alanyl-​D-​isoglutamine
Packaging
5mg
Price
$2310
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CRB0004257
Product name
N-ACETYL-BETA-GLUCOSAMINYL-N-ACETYLMURAMYL-ALANYLISOGLUTAMINE
Purity
95.00%
Packaging
5MG
Price
$499.84
Updated
2021/12/16
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GMDP Chemical Properties,Usage,Production

Description

N-acetyl-β-D-glucosaminyl-( 1→4)-N-acetylmuramyl-L-alanyl-D-isoglutamine was launched in Russia for hospital-related infections, psoriasis, cervical precancerous lesions and ophthalmic keratitis caused by herpes. It was found to be less pyrogenic than MDP, the minimally active component of Freund's complete adjuvant. While chemical synthesis is possible, a less laborious method (3 steps) involves the enzymatic degradation of a bacterial peptidoglycan. GDMP is orally active with a low toxicity that acts as an adjuvant to highly purified protein antigens to stimulate the induction of CD8* T-cell response. It was also able to reduce the levels of TNF-α, IL-1α and hypoglycemia induced by LPS administration and to inhibit systemic response to endotoxin.

Originator

Peptech (Australia)

Uses

N-?Acetyl-?β-?D-?glucosaminyl-?N-?acetylmuramyl-?L-?alanyl-?D-?isoglutamine acts as an immunnomodulator or immunostimulant in the treatment of various auto-immune diseases.

Definition

ChEBI: Glucosaminylmuramyl dipeptide is a dipeptide.

brand name

Likopid

GMDP Preparation Products And Raw materials

Raw materials

Preparation Products

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GMDP Suppliers

China 4 Switzerland 1 United Kingdom 1 United States 3 Global 9
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
EMD Biosciences, Inc.
Tel
--
Fax
--
Email
technical@calbiochem.com
Country
United States
ProdList
6529
Advantage
66
MP Biomedicals, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6561
Advantage
81

70280-03-4, GMDPRelated Search:

N-acetyl-nor-muramyl-L-alanyl-D-isoglutamine ISO-PROPYL 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSIDE (R)-(+)-2-METHOXYPROPIONAMIDE D-GLUTAMIC ACID ALPHA-AMIDE HYDROCHLORIDE ETHYL 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSIDE BUTYL 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSIDE N,N'-Diacetylchitobiose PROPYL 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSIDE 2(2-HYDROXYETHOXY)ACETAMIDE Muramyl Dipeptide H-ALA-D-GLU-NH2 2-ACETAMIDO-2-DEOXY-3-O-METHYL-D-GLUCOPYRANOSE GMDP

  • d-alpha-glutamine,n-(n-acetyl-4-o-(2-(acetylamino)-2-deoxy-beta-d-glucopyrano
  • glucosaminylmuramyldipeptide
  • n-acetyl-beta-glucosaminyl-(1-4)-n-acetylmuramyl-l-alanyl-d-isoglutamine
  • n-acetyl-beta-glucosaminyl-n-acetylmuramyl-alanylisoglutamine
  • n-acetylglucosaminyl-n-acetylmuramyl-l-alanyl-d-isoglutamine
  • syl)muramoyl)-l-alanyl-
  • 4-(2-acetamido-2-deoxy-B-D-*glucopyranosyl)-N-ace
  • N-Acetyl-D-glucosaminyl-(b1,4)-N-acetylmuramyl-L-alanyl-D-io
  • 4-(2-ACETAMIDO-2-DEOXY-B-D- &
  • 4-(2-acetamido-2-deoxy-β-d-glucopyranosyl)-n-acetylmuramyl-l-ala-d-glu amide
  • d-glcnac-β-(1→4)-n-acetylmuramyl-l-ala-d-isoglutamine
  • D-GLCNAC-BETA-(1->4)-N-ACETYLMURAMYL-L-ALA-D-ISOGLUTAMINE
  • GMDP
  • N-ACETYL-D-GLUCOSAMINYL-(BETA1,4)-N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE
  • 4-(2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSYL)-N-ACETYLMURAMYL-L-ALA-D-GLU AMIDE
  • N-Acetyl-beta-D-Glucosaminyl-N-Acetylmuramyl-L-Alanyl-D-Isoglutamine
  • D-α-Glutamine, N-[N-acetyl-4-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]muramoyl]-L-alanyl-
  • (4R)-4-((2S)-2-((2R)-2-(((3R,4R,5S,6R)-3-acetamido-5-(((2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)propanamido)propanamido)-5-amino-5-oxopentanoic acid
  • N-?Acetyl-?β-?D-?glucosaminyl-?N-?acetylmuramyl-?L-?alanyl-?D-?isoglutamine
  • 70280-03-4
  • C27H45N5O16
  • Dipeptides and Tripeptides
  • Dipeptides
  • BioChemical
  • Amino Acids and Peptides
  • Biochemicals and Reagents