ChemicalBook > CAS DataBase List > 14(R),15(S)-EPOXY-(5Z,8Z,11Z)-EICOSATRIENOIC ACID

14(R),15(S)-EPOXY-(5Z,8Z,11Z)-EICOSATRIENOIC ACID

Product Name
14(R),15(S)-EPOXY-(5Z,8Z,11Z)-EICOSATRIENOIC ACID
CAS No.
105304-92-5
Chemical Name
14(R),15(S)-EPOXY-(5Z,8Z,11Z)-EICOSATRIENOIC ACID
Synonyms
14[R],15[S]-EET;14(R),15(S)-epoxy-(5Z,8Z,11Z)-*eicosatrienoic aci;14(R),15(S)-EPOXY-(5Z,8Z,11Z)-EICOSATRIENOIC ACID
CBNumber
CB7204959
Molecular Formula
C20H32O3
Formula Weight
320.47
MOL File
105304-92-5.mol
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14(R),15(S)-EPOXY-(5Z,8Z,11Z)-EICOSATRIENOIC ACID Property

storage temp. 
−20°C
solubility 
Ethanol: Soluble
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Safety

Hazard Codes 
F,Xi
Risk Statements 
11-36/37/38
Safety Statements 
16-26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
28631
Product name
14S(15R)-EET
Packaging
10μg
Price
$118
Updated
2023/06/20
Cayman Chemical
Product number
28631
Product name
14S(15R)-EET
Packaging
100μg
Price
$824
Updated
2023/06/20
Cayman Chemical
Product number
28631
Product name
14S(15R)-EET
Packaging
25μg
Price
$281
Updated
2023/06/20
Cayman Chemical
Product number
28631
Product name
14S(15R)-EET
Packaging
50μg
Price
$502
Updated
2023/06/20
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14(R),15(S)-EPOXY-(5Z,8Z,11Z)-EICOSATRIENOIC ACID Chemical Properties,Usage,Production

Uses

14S(15R)-EET is an endogenous epoxytrienoic acid derivative that mainly exists in rat organs. By studying its metabolic process, it was found that its stereoselective hydration and formation of chiral diols were significantly affected by epoxidase. Different 14,15-EET enantiomers showed different regions and stereochemistry of hydration reactions, among which 14(R),15(S)-EET showed specific hydration for C15. These findings reveal the important role of epoxidase in the metabolism of endogenous EETs, and the differences in enzyme affinity and reaction rate for individual EET enantiomers may lead to their stereoselective metabolism[1].

Definition

ChEBI: 14,15-Epoxy-5,8,11-eicosatrienoic acid is a long-chain fatty acid.

References

[1] Zeldin DC, et al. Metabolism of epoxyeicosatrienoic acids by cytosolic epoxide hydrolase: substrate structural determinants of asymmetric catalysis. Arch Biochem Biophys. 1995 Jan 10;316(1):443-51. DOI:10.1006/abbi.1995.1059

14(R),15(S)-EPOXY-(5Z,8Z,11Z)-EICOSATRIENOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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14(R),15(S)-EPOXY-(5Z,8Z,11Z)-EICOSATRIENOIC ACID Suppliers

ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Cayman Chemical Company
Tel
800-364-9897
Email
sales@caymanchem.com
Country
China
ProdList
6838
Advantage
58
DAYANG CHEM (HANGZHOU) CO.,LTD
Tel
+86-88938639 +86-17705817739
Email
info@dycnchem.com
Country
China
ProdList
53899
Advantage
58

105304-92-5, 14(R),15(S)-EPOXY-(5Z,8Z,11Z)-EICOSATRIENOIC ACIDRelated Search:


  • 14[R],15[S]-EET
  • 14(R),15(S)-EPOXY-(5Z,8Z,11Z)-EICOSATRIENOIC ACID
  • 14(R),15(S)-epoxy-(5Z,8Z,11Z)-*eicosatrienoic aci
  • 105304-92-5
  • BioChemical
  • Biochemicals and Reagents
  • Unsaturated fatty acids and derivatives
  • Polyunsaturated
  • Lipids
  • Epoxy acids
  • Fatty Acids