14(R),15(S)-EPOXY-(5Z,8Z,11Z)-EICOSATRIENOIC ACID
- Product Name
- 14(R),15(S)-EPOXY-(5Z,8Z,11Z)-EICOSATRIENOIC ACID
- CAS No.
- 105304-92-5
- Chemical Name
- 14(R),15(S)-EPOXY-(5Z,8Z,11Z)-EICOSATRIENOIC ACID
- Synonyms
- 14[R],15[S]-EET;14(R),15(S)-epoxy-(5Z,8Z,11Z)-*eicosatrienoic aci;14(R),15(S)-EPOXY-(5Z,8Z,11Z)-EICOSATRIENOIC ACID
- CBNumber
- CB7204959
- Molecular Formula
- C20H32O3
- Formula Weight
- 320.47
- MOL File
- 105304-92-5.mol
14(R),15(S)-EPOXY-(5Z,8Z,11Z)-EICOSATRIENOIC ACID Property
- storage temp.
- −20°C
- solubility
- Ethanol: Soluble
Safety
- Hazard Codes
- F,Xi
- Risk Statements
- 11-36/37/38
- Safety Statements
- 16-26-36
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- 28631
- Product name
- 14S(15R)-EET
- Packaging
- 10μg
- Price
- $118
- Updated
- 2023/06/20
- Product number
- 28631
- Product name
- 14S(15R)-EET
- Packaging
- 100μg
- Price
- $824
- Updated
- 2023/06/20
- Product number
- 28631
- Product name
- 14S(15R)-EET
- Packaging
- 25μg
- Price
- $281
- Updated
- 2023/06/20
- Product number
- 28631
- Product name
- 14S(15R)-EET
- Packaging
- 50μg
- Price
- $502
- Updated
- 2023/06/20
14(R),15(S)-EPOXY-(5Z,8Z,11Z)-EICOSATRIENOIC ACID Chemical Properties,Usage,Production
Uses
14S(15R)-EET is an endogenous epoxytrienoic acid derivative that mainly exists in rat organs. By studying its metabolic process, it was found that its stereoselective hydration and formation of chiral diols were significantly affected by epoxidase. Different 14,15-EET enantiomers showed different regions and stereochemistry of hydration reactions, among which 14(R),15(S)-EET showed specific hydration for C15. These findings reveal the important role of epoxidase in the metabolism of endogenous EETs, and the differences in enzyme affinity and reaction rate for individual EET enantiomers may lead to their stereoselective metabolism[1].
Definition
ChEBI: 14,15-Epoxy-5,8,11-eicosatrienoic acid is a long-chain fatty acid.
References
[1] Zeldin DC, et al. Metabolism of epoxyeicosatrienoic acids by cytosolic epoxide hydrolase: substrate structural determinants of asymmetric catalysis. Arch Biochem Biophys. 1995 Jan 10;316(1):443-51. DOI:10.1006/abbi.1995.1059
14(R),15(S)-EPOXY-(5Z,8Z,11Z)-EICOSATRIENOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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