(+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID
- Product Name
- (+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID
- CAS No.
- 81276-03-1
- Chemical Name
- (+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID
- Synonyms
- 14,15-EET;14(15)-EPETRE;(+/-)14,15-EET;(+/-)14(15)-EPETRE;14,15-Epoxyeicosatrienoic acid;14,15-epoxy-5,8,11-eicosatrienoicacid;(+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID;(+/-)14(15)-EPOXY-5Z,8Z,11Z-EICOSATRIENOIC ACID;5,8,11-Tridecatrienoic acid, 13-(3-pentyl-2-oxiranyl)-;"14,15-Epoxyeicosa-5,8,11-trienoic Acid D11 (14,15-EET)"
- CBNumber
- CB2767998
- Molecular Formula
- C20H32O3
- Formula Weight
- 320.47
- MOL File
- 81276-03-1.mol
(+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID Property
- Boiling point:
- 464.5±33.0 °C(Predicted)
- Density
- 0.983±0.06 g/cm3(Predicted)
- Flash point:
- 14 °C
- storage temp.
- −20°C
- pka
- 4.78±0.10(Predicted)
- form
- Liquid (Density: 0.983±0.06 g/cm3)
- color
- Colorless to light yellow
Safety
- Hazard Codes
- F,Xi
- Risk Statements
- 11-36/37/38
- Safety Statements
- 16-26-36-7
- RIDADR
- UN 1170 3/PG 2
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
N-Bromosuccinimide Price
- Product number
- 412022
- Product name
- 14,15-Epoxyeicosatrienoic Acid
- Packaging
- 50g
- Price
- $333
- Updated
- 2021/12/16
- Product number
- INB0001879
- Product name
- (+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.86
- Updated
- 2021/12/16
(+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID Chemical Properties,Usage,Production
Uses
Epoxyeicosatrienoic Acid (EET) has antihypertensive and anti-inflammatory properties and play a role in the maintenance of renal vascular function. N,?N''-?dicyclohexylurea (DCU) increased release of 14,15-EET when the cells were stimulated with a calcium ionophore.Also, it is derived from Arachidonic Acid >97% (A765000), which is an essential fatty acid and a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. Arachidonic Acid occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and Arachidonic Acid is also a constituent of animal phosphatides.
Definition
ChEBI: 14,15-Epoxy-5,8,11-eicosatrienoic acid is a long-chain fatty acid.
in vivo
14,15-Epoxyeicosatrienoic acid (0.3 mg/kg i.v.) inhibits platelet aggregation in mouse cerebral arterioles[2].
14,15-Epoxyeicosatrienoic acid (200 ng/ml) infusion into the hippocampus reversed Aβ deposition in the brains of 6-month-old male FAD mice[1].
IC 50
Human Endogenous Metabolite
(+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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