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AM 404

Product Name
AM 404
CAS No.
183718-77-6
Chemical Name
AM 404
Synonyms
AM 404;N-(4-HYDROXYPHENYL)-ARACHIDONAMIDE;N-(4-HYDROXYPHENYL)ARACHIDONYLAMIDE;N-(4-HYDROXYPHENYL) ARACHIDONOYLAMIDE;ARACHIDONOYLAMIDE, N-(4-HYDROXYPHENYL);N-(4-HYDROXYPHENYL)-5Z,8Z,11Z,14Z-EICOSATETRENAMIDE;N-(4-HYDROXYPHENYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE;(all-Z)-N-(4-Hydroxyphenyl)-5,8,11,14-eicosatetraenaMide;(5Z,8Z,11Z,14Z)-N-(4-Hydroxyphenyl)-5,8,11,14-eicosatetraenaMide;5,8,11,14-Eicosatetraenamide, N-(4-hydroxyphenyl)-, (5Z,8Z,11Z,14Z)-
CBNumber
CB7205077
Molecular Formula
C26H37NO2
Formula Weight
395.58
MOL File
183718-77-6.mol
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AM 404 Property

Boiling point:
579.4±50.0 °C(Predicted)
Density 
1.007±0.06 g/cm3(Predicted)
Flash point:
14 °C
storage temp. 
-20°C
solubility 
ethanol: 24 mg/mL Photosensitive solution.
form 
solution
pka
10.11±0.26(Predicted)
color 
Colorless to light yellow
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Safety

Hazard Codes 
F
Risk Statements 
36/37/38-11
Safety Statements 
7-16
RIDADR 
UN 1170 3/PG 2
WGK Germany 
1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H1911
Product name
N-(4-Hydroxyphenyl)-arachidonylamide
Purity
≥98%, ethanol solution
Packaging
10mg
Price
$181
Updated
2025/07/31
Cayman Chemical
Product number
90060
Product name
AM404
Purity
≥98%
Packaging
5mg
Price
$25
Updated
2024/03/01
Cayman Chemical
Product number
90060
Product name
AM404
Purity
≥98%
Packaging
10mg
Price
$45
Updated
2024/03/01
Cayman Chemical
Product number
90060
Product name
AM404
Purity
≥98%
Packaging
50mg
Price
$186
Updated
2024/03/01
Cayman Chemical
Product number
90060
Product name
AM404
Purity
≥98%
Packaging
100mg
Price
$324
Updated
2024/03/01
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AM 404 Chemical Properties,Usage,Production

Uses

It is a metabolite of the well-known analgesic Paracetamol. ase (FAAH) in vivo.

Uses

Potentiates the activity of endogenous anandamide by blocking its re-uptake into presynaptic membranes. AM404 selectively inhibits the carrier-mediated transport of anandamide without affecting anandamide hydrolysis.

in vivo

AM404 (1-5 mg/kg, i.p.) exerts dose-dependent anxiolytic-like effects in the three models: elevated plus maze, defensive withdrawal and separation-induced ultrasonic vocalizations.

Animal Model:Adult male Sprague-Dawley rats (250-300?g)[2]
Dosage:2.5-10?mg/kg
Administration:Intraperitoneal (i.p.)
Result:Caused a dose-dependent increase in anandamide levels in prefrontal cortex, hippocampus and thalamus.

storage

-20°C

AM 404 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from AM 404 manufacturers

RongNa Biotechnology Co.,Ltd
Product
AM 404 183718-77-6
Price
US $10.00/ASSAYS
Min. Order
1ASSAYS
Purity
99%
Supply Ability
1 ton
Release date
2025-08-29

183718-77-6, AM 404Related Search:


  • N-(4-HYDROXYPHENYL)-ARACHIDONAMIDE
  • N-(4-HYDROXYPHENYL) ARACHIDONOYLAMIDE
  • N-(4-HYDROXYPHENYL)ARACHIDONYLAMIDE
  • N-(4-HYDROXYPHENYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE
  • N-(4-HYDROXYPHENYL)-5Z,8Z,11Z,14Z-EICOSATETRENAMIDE
  • ARACHIDONOYLAMIDE, N-(4-HYDROXYPHENYL)
  • AM 404
  • (5Z,8Z,11Z,14Z)-N-(4-Hydroxyphenyl)-5,8,11,14-eicosatetraenaMide
  • (all-Z)-N-(4-Hydroxyphenyl)-5,8,11,14-eicosatetraenaMide
  • 5,8,11,14-Eicosatetraenamide, N-(4-hydroxyphenyl)-, (5Z,8Z,11Z,14Z)-
  • 183718-77-6
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