AM 404
- Product Name
- AM 404
- CAS No.
- 183718-77-6
- Chemical Name
- AM 404
- Synonyms
- AM 404;N-(4-HYDROXYPHENYL)-ARACHIDONAMIDE;N-(4-HYDROXYPHENYL)ARACHIDONYLAMIDE;N-(4-HYDROXYPHENYL) ARACHIDONOYLAMIDE;ARACHIDONOYLAMIDE, N-(4-HYDROXYPHENYL);N-(4-HYDROXYPHENYL)-5Z,8Z,11Z,14Z-EICOSATETRENAMIDE;N-(4-HYDROXYPHENYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE;(all-Z)-N-(4-Hydroxyphenyl)-5,8,11,14-eicosatetraenaMide;(5Z,8Z,11Z,14Z)-N-(4-Hydroxyphenyl)-5,8,11,14-eicosatetraenaMide;5,8,11,14-Eicosatetraenamide, N-(4-hydroxyphenyl)-, (5Z,8Z,11Z,14Z)-
- CBNumber
- CB7205077
- Molecular Formula
- C26H37NO2
- Formula Weight
- 395.58
- MOL File
- 183718-77-6.mol
AM 404 Property
- Boiling point:
- 579.4±50.0 °C(Predicted)
- Density
- 1.007±0.06 g/cm3(Predicted)
- Flash point:
- 14 °C
- storage temp.
- -20°C
- solubility
- ethanol: 24 mg/mL Photosensitive solution.
- form
- solution
- pka
- 10.11±0.26(Predicted)
- color
- Colorless to light yellow
Safety
- Hazard Codes
- F
- Risk Statements
- 36/37/38-11
- Safety Statements
- 7-16
- RIDADR
- UN 1170 3/PG 2
- WGK Germany
- 1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- H1911
- Product name
- N-(4-Hydroxyphenyl)-arachidonylamide
- Purity
- ≥98%, ethanol solution
- Packaging
- 10mg
- Price
- $181
- Updated
- 2025/07/31
- Product number
- 90060
- Product name
- AM404
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $25
- Updated
- 2024/03/01
- Product number
- 90060
- Product name
- AM404
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $45
- Updated
- 2024/03/01
- Product number
- 90060
- Product name
- AM404
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $186
- Updated
- 2024/03/01
- Product number
- 90060
- Product name
- AM404
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $324
- Updated
- 2024/03/01
AM 404 Chemical Properties,Usage,Production
Uses
It is a metabolite of the well-known analgesic Paracetamol. ase (FAAH) in vivo.
Uses
Potentiates the activity of endogenous anandamide by blocking its re-uptake into presynaptic membranes. AM404 selectively inhibits the carrier-mediated transport of anandamide without affecting anandamide hydrolysis.
in vivo
AM404 (1-5 mg/kg, i.p.) exerts dose-dependent anxiolytic-like effects in the three models: elevated plus maze, defensive withdrawal and separation-induced ultrasonic vocalizations.
| Animal Model: | Adult male Sprague-Dawley rats (250-300?g)[2] |
| Dosage: | 2.5-10?mg/kg |
| Administration: | Intraperitoneal (i.p.) |
| Result: | Caused a dose-dependent increase in anandamide levels in prefrontal cortex, hippocampus and thalamus. |
storage
-20°C
AM 404 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from AM 404 manufacturers
- Product
- AM 404 183718-77-6
- Price
- US $10.00/ASSAYS
- Min. Order
- 1ASSAYS
- Purity
- 99%
- Supply Ability
- 1 ton
- Release date
- 2025-08-29