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NORCODEINE

Product Name
NORCODEINE
CAS No.
467-15-2
Chemical Name
NORCODEINE
Synonyms
NORCODEINE;Norcodeinum;N-Norcodeine;17-Norcodeine;(-)-N-Norcodeine;N-Demethylcodeine;N-Desmethylcodeine;Codeinone Impurity 5;3-O-Methylnormorphine;N-Demethylated codeine
CBNumber
CB7211845
Molecular Formula
C17H19NO3
Formula Weight
285.34
MOL File
467-15-2.mol
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NORCODEINE Property

Melting point:
1850C
Boiling point:
467.7±45.0 °C(Predicted)
Density 
1.37±0.1 g/cm3(Predicted)
Flash point:
9℃
storage temp. 
-20°C
solubility 
DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 10 mg/ml
form 
A crystalline solid
pka
pKa 9.23± 0.01(H2O,t =25±0.1,I=0.15(KCl)Ar)(Approximate)
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Safety

Hazard Codes 
F,T
Risk Statements 
11-23/24/25-39/23/24/25
Safety Statements 
7-16-36/37-45
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P311Call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N-005
Product name
Norcodeine solution
Purity
1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$38.5
Updated
2022/05/15
Cayman Chemical
Product number
23816
Product name
Norcodeine
Packaging
5mg
Price
$72
Updated
2023/06/20
Cayman Chemical
Product number
23816
Product name
Norcodeine
Packaging
10mg
Price
$108
Updated
2023/06/20
AK Scientific
Product number
4281CR
Product name
Norcodeine
Packaging
10mg
Price
$221
Updated
2021/12/16
Chemtos
Product number
N-4302
Product name
NorcodeineLabeledd3
Packaging
10mg
Price
$1500
Updated
2021/12/16
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NORCODEINE Chemical Properties,Usage,Production

Chemical Properties

Crystalline Solid

Uses

(-)-N-Norcodeine is a metabolite of Codeine. Morphine derivative.

Definition

ChEBI: A morphinane-like compound that is the N-demethylated derivative of codeine.

Purification Methods

It crystallises from acetone or ethyl acetate. [Speyer & Walther Chem Ber 63 822 1930.] The hydrochloride has m 309o(dec) when crystallised from H2O. [Beilstein 18 III/IV 8091.]

NORCODEINE Preparation Products And Raw materials

Raw materials

Preparation Products

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NORCODEINE Suppliers

467-15-2, NORCODEINERelated Search:


  • NORCODEINE
  • (5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-3-methoxymorphinan-6-ol
  • 7,8-didehydro-4,5-alpha-epoxy-3-methoxy-morphinan-6-alpha-o
  • 7,8-Didehydro-4,5-alpha-epoxy-3-methoxymorphinan-6-alpha-ol
  • 7,8-didehydro-4,5-epoxy-3-methoxy-,(5-alpha,6-alpha)-morphinan-6-o
  • Morphinan-6alpha-ol, 7,8-didehydro-4,5alpha-epoxy-3-methoxy-
  • Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-, (5alpha,6alpha)-
  • N-Demethylated codeine
  • N-Demethylcodeine
  • N-Desmethylcodeine
  • N-Norcodeine
  • Normorphine 3-methyl ether
  • (5a,6a)-7,8-Didehydro-4,5-epoxy-3-methoxy-morphinan-6-ol
  • 17-Norcodeine
  • 3-O-Methylnormorphine
  • Norcodeinum
  • NORCODEINE,1.0MG/MLINMETHANOL
  • NORCODEINE TRIFLUOROACETATE
  • HKOIXWVRNLGFOR-KOFBORESSA-N
  • 7,8-Didehydro-4,5α-epoxy-3-methoxymorphinan-6α-ol
  • Norcodeine solution
  • Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-, (5α,6α)-
  • (-)-N-Norcodeine
  • 4,5α-epoxy-3-methoxy-7,8-didehydromorphinan-6α-ol(norcodeine)
  • Codeinone Impurity 5
  • Codeine Monohydrate Impurity H
  • Codeine Monohydrate EP Impurity H
  • Carfentrazone-ethyl Impurity 2
  • 467-15-2
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals