ChemicalBook > CAS DataBase List > 4-METHYLUMBELLIFERYL OLEATE

4-METHYLUMBELLIFERYL OLEATE

Product Name
4-METHYLUMBELLIFERYL OLEATE
CAS No.
18323-58-5
Chemical Name
4-METHYLUMBELLIFERYL OLEATE
Synonyms
4-MU-OLEATE;Einecs 242-210-7;4-METHYLUMBELLIFERYL OLEATE;4-Methylumbelliferone oleate;Oleoyl 4-MethyluMbelliferone;4-MethylumbelliferylOleateA.R.;7-Hydroxy-4-MethylcouMarin Oleate;4-methylumbrellaketoneoleate,4-MUO;OLEIC ACID-4-METHYLUMBELLIFERYL ESTER;4-Methyl-2-oxo-2H-chroMen-7-yl oleate
CBNumber
CB7212923
Molecular Formula
C28H40O4
Formula Weight
440.61
MOL File
18323-58-5.mol
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4-METHYLUMBELLIFERYL OLEATE Property

Melting point:
37-38 °C (lit.)
Boiling point:
471.81°C (rough estimate)
Density 
1.023
refractive index 
1.4840 (estimate)
Flash point:
281.3℃
storage temp. 
-20°C
solubility 
2-methoxyethanol: soluble
form 
Solid
color 
Colorless to Pale Yellow Oil
Appearance
Solid Powder
BRN 
4887028
CAS DataBase Reference
18323-58-5(CAS DataBase Reference)
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Safety

WGK Germany 
3
8-10
HS Code 
29322090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
75164
Product name
4-Methylumbelliferyl oleate
Purity
suitable for fluorescence, ≥95% (HPCE)
Packaging
25mg
Price
$102
Updated
2025/07/31
Sigma-Aldrich
Product number
75164
Product name
4-Methylumbelliferyl oleate
Purity
suitable for fluorescence, ≥95% (HPCE)
Packaging
100mg
Price
$315
Updated
2025/07/31
Cayman Chemical
Product number
19590
Product name
4-Methylumbelliferyl Oleate
Purity
≥98%
Packaging
25mg
Price
$48
Updated
2024/03/01
Cayman Chemical
Product number
19590
Product name
4-Methylumbelliferyl Oleate
Purity
≥98%
Packaging
50mg
Price
$85
Updated
2024/03/01
Cayman Chemical
Product number
19590
Product name
4-Methylumbelliferyl Oleate
Purity
≥98%
Packaging
100mg
Price
$121
Updated
2024/03/01
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4-METHYLUMBELLIFERYL OLEATE Chemical Properties,Usage,Production

Description

4-Methylumbelliferyl (4-MU) oleate is a fluorogenic substrate for acid and alkaline lipases. It is cleaved by lipases, liberating 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.

Chemical Properties

Colourless Oil

Uses

Fluorogenic substrate for lipases.

Uses

4-Methylumbelliferyl oleate has been used:

  • as a substrate to assay the activity of non-specific esterases
  • to determine lipase activity
  • as a substrate to evaluate pancreatic lipase inhibitory activity

Uses

4-Methylumbelliferyl oleate can act as Fatty acyl esters for use as fluorogenic substrates to continuously follow the hydrolytic activity of carboxylesterases, such as acid and alkaline lipases.

References

[1] M L ARMSTRONG. Lipid metabolism in xanthomatous skin of hypercholesterolemic rabbits.[J]. American Journal of Pathology, 1986, 125 2: 339-348.
[2] BERNARD J MONCLA K M P. Oleate lipase activity in Gardnerella vaginalis and reconsideration of existing biotype schemes.[J]. ACS Applied Energy Materials, 2009: 78. DOI: 10.1186/1471-2180-9-78
[3] AKIHIRO OGAWA. Lactobacillus gasseri SBT2055 suppresses fatty acid release through enlargement of fat emulsion size in vitro and promotes fecal fat excretion in healthy Japanese subjects.[J]. Lipids in Health and Disease, 2015, 14: 20. DOI: 10.1186/s12944-015-0019-0

Excitation / Emission Maximum

330 nm (pH 4.6), 370 nm (pH 7.4), 385 nm (pH 10.4)/445-454 nm

4-METHYLUMBELLIFERYL OLEATE Preparation Products And Raw materials

Raw materials

Preparation Products

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18323-58-5, 4-METHYLUMBELLIFERYL OLEATERelated Search:


  • OLEIC ACID-4-METHYLUMBELLIFERYL ESTER
  • 4-METHYLUMBELLIFERYL OLEATE
  • 4-MU-OLEATE
  • 4-methyl-2-oxo-2H-1-benzopyran-7-yl oleate
  • 4-METHYLUMBELLIFERYL OLEATE, FOR FLUORES CENCE
  • 4-MethylumbelliferylOleateA.R.
  • (9Z)-9-Octadecenoic Acid 4-Methyl-2-oxo-2H-1-benzopyran-7-yl Ester
  • (Z)-9-Octadecenoic acid (4-methyl-2-oxo-2H-1-benzopyran-7-yl) ester
  • (Z)-9-Octadecenoic acid 4-methyl-2-oxo-2H-1-benzopyran-7-yl ester
  • 4-Methylumbelliferone oleate
  • 9-Octadecenoic acid (Z)-, 4-methyl-2-oxo-2H-1-benzopyran-7-yl ester
  • Einecs 242-210-7
  • (9Z)-octadec-9-enoic acid 4-methyl-2-oxo-2H-chromen-7-yl ester
  • 7-Hydroxy-4-MethylcouMarin Oleate
  • Oleoyl 4-MethyluMbelliferone
  • 4-Methyl-2-oxo-2H-chroMen-7-yl oleate
  • 9-Octadecenoic acid (9Z)-, 4-methyl-2-oxo-2H-1-benzopyran-7-yl ester
  • (4-Methyl-2-oxochromen-7-yl) (Z)-octadec-9-enoate
  • 4-Methylumbelliferyl oleate, suitable for fluorescence, ≥95%
  • 4-methylumbrellaketoneoleate,4-MUO
  • 4-Methylumbelliferyl oleate, Fluorogenic substrate for lipases
  • 18323-58-5
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