4-METHYLUMBELLIFERYL OLEATE Property

Melting point:

37-38 °C (lit.)

Boiling point:

471.81°C (rough estimate)

Density 

1.023

refractive index 

1.4840 (estimate)

Flash point:

281.3℃

storage temp. 

-20°C

solubility 

2-methoxyethanol: soluble

form 

Solid

color 

Colorless to Pale Yellow Oil

BRN 

4887028

CAS DataBase Reference

18323-58-5(CAS DataBase Reference)

Safety

WGK Germany 

3

F 

8-10

HS Code 

29322090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

4-METHYLUMBELLIFERYL OLEATE Chemical Properties,Usage,Production

Description

4-Methylumbelliferyl (4-MU) oleate is a fluorogenic substrate for acid and alkaline lipases. It is cleaved by lipases, liberating 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.

Chemical Properties

Colourless Oil

Uses

Fluorogenic substrate for lipases.

Uses

4-Methylumbelliferyl oleate has been used:

• as a substrate to assay the activity of non-specific esterases
• to determine lipase activity
• as a substrate to evaluate pancreatic lipase inhibitory activity

Uses

4-Methylumbelliferyl oleate can act as Fatty acyl esters for use as fluorogenic substrates to continuously follow the hydrolytic activity of carboxylesterases, such as acid and alkaline lipases.