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AMBRETTOLIDE

Product Name
AMBRETTOLIDE
CAS No.
28645-51-4
Chemical Name
AMBRETTOLIDE
Synonyms
Nsc 31697;FEMA 2555;AMBRETTOLIDE;Fema no. 2555;Einecs 249-120-7;HEXADECEN-8-OLIDE;Ambrettolide 1832003;OMEGA-6-HEXADECENLACTONE;Oxacycloheptadec-10-en-2-on;1-oxacycloheptadec-10-en-2-one
CBNumber
CB7213218
Molecular Formula
C16H28O2
Formula Weight
252.39
MOL File
28645-51-4.mol
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AMBRETTOLIDE Property

Boiling point:
185-190 °C16 mm Hg(lit.)
Density 
0.956 g/mL at 25 °C(lit.)
vapor pressure 
0.003Pa at 25℃
refractive index 
n20/D 1.479(lit.)
FEMA 
4145 | ISOAMBRETTOLIDE
Flash point:
>230 °F
storage temp. 
Refrigerator
solubility 
Chloroform (Sparingly), Methanol (Sparingly)
form 
Oil
color 
Clear Colorless
Odor
at 10.00 % in dipropylene glycol. sweet musk ambrette fruity waxy fatty
Odor Type
musk
Water Solubility 
15μg/L at 25℃
JECFA Number
1991
LogP
6.7 at 23℃
EPA Substance Registry System
Oxacycloheptadec-10-en-2-one (28645-51-4)
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Safety

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
26-36
WGK Germany 
2
Toxicity
Both the acute oral LD50 value in rats and the acute dermal LD50 value in rabbits exceeded 5 g/kg(Wohl, 1974).
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W414522
Product name
Isoambrettolide
Purity
≥97%, FG
Packaging
SAMPLE-K
Price
$50
Updated
2024/03/01
Sigma-Aldrich
Product number
W414522
Product name
Isoambrettolide
Purity
≥97%, FG
Packaging
100g
Price
$70
Updated
2024/03/01
Sigma-Aldrich
Product number
W414522
Product name
Isoambrettolide
Purity
≥97%, FG
Packaging
1kg
Price
$400
Updated
2024/03/01
Sigma-Aldrich
Product number
W414522
Product name
Isoambrettolide
Purity
≥97%, FG
Packaging
100G-K
Price
$70
Updated
2023/06/20
Sigma-Aldrich
Product number
W414522
Product name
Isoambrettolide
Purity
≥97%, FG
Packaging
1KG-K
Price
$400
Updated
2023/06/20
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AMBRETTOLIDE Chemical Properties,Usage,Production

Chemical Properties

AMBRETTOLIDE is not reported as being found in nature, in contrast to (Z)-7-hexadecen-16-olide, which occurs in ambrette seed oil and which is also referred to as ambrettolide. It is a colorless to slightly yellow liquid, d204 0.949–0.957, n20D 1.477–1.482, with an intense and powerful musk odor. It is prepared by treating aleuritic acid (9,10,16-trihydroxyhexadecanoic acid) with trimethyl orthoformate to give a dioxolane derivative. Reaction with acetic anhydride yields ??-acetoxy (E)-9-hexadecenoic acid methyl ester. This is lactonized with potassium hydroxide to give the title compound .

Occurrence

Found in oil of ambrette seed[Givaudan Index, 1961).

Uses

Ambrettolide is a macrocyclic lactone that naturally occurs in ambrette seed oil. Ambrettolide is nontoxic, has a musky odour, and is commonly used as a fixative in perfume formulations.

Definition

ChEBI: Isoambrettolide is a macrolide.

Preparation

From bromohexadecenoic acid(Bedoukian, 1967).

Flammability and Explosibility

Not classified

AMBRETTOLIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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AMBRETTOLIDE Suppliers

China 44 Germany 2 India 4 South Korea 1 United Kingdom 2 United States 28 Global 81
jiliang chemicals
Tel
21-62165282 15801962796;
Fax
021 61153784
Email
bidingchem@163.com
Country
China
ProdList
1165
Advantage
60
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14059
Advantage
65
Qingdao Free Trade Zone United International Co.,Ltd.
Tel
0532-83893697 18561902820
Fax
83893695
Email
sissili@unitedint.com
Country
China
ProdList
352
Advantage
58
Shanghai Youd Chemical Technology Co., Ltd.
Tel
15821801668
Fax
021-37910267
Email
cong44@126.com
Country
China
ProdList
291
Advantage
58
Shanghai Hao Yun Chemical Science Co.,Ltd.
Tel
021-68367562 15002147577;
Fax
021-68369562
Email
sales@haoyunchem.com
Country
China
ProdList
463
Advantage
55
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9503
Advantage
50
Shanghai Witofly Chemical Co. ,Ltd.
Tel
021-021-50630626 18964684208
Email
sales@witofly.com
Country
China
ProdList
1150
Advantage
55
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400-6387771-6038 18902104717
Email
sales@heowns.com
Country
China
ProdList
20512
Advantage
60
Shanghai Shuai Sun Industrial Co., Ltd.
Tel
021-37590756 57450129
Fax
021-57450128
Country
China
ProdList
4287
Advantage
58
Chengdu Saint - Kay Biotechnology Co., Ltd.
Tel
028-85157043 15882256948
Email
676046971@qq.com
Country
China
ProdList
4392
Advantage
58
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View Lastest Price from AMBRETTOLIDE manufacturers

Career Henan Chemical Co
Product
AMBRETTOLIDE 28645-51-4
Price
US $2.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
ask
Release date
2019-12-18

28645-51-4, AMBRETTOLIDERelated Search:

OXACYCLOHEPTADEC-10-EN-2-ONE, TECH cis-Iso ambrettolide OXACYCLOHEPTADEC-10-EN-2-ONE oxacycloheptadec-14-en-2-one AMBRETTOLIDE LG,(Z)-Oxacycloheptadec-8-en-2-on oxacycloheptadec-13-en-2-one Ambrettolide, Oxacycloheptadec-10-en-2-one,oxacycloheptadec-7-en-2-one ,Ambrettolide, Oxacycloheptadec-10-en-2-one,OXACYCLOHEPTADEC-8-EN-2-ONE,AMBRETTOLIDE

  • AMBRETTOLIDE
  • OMEGA-6-HEXADECENLACTONE
  • Oxacycloheptadec-10-en-2-on
  • 16-Hydroxy-9-hexadecenoic acid lactone
  • 1-Oxacycloheptadeca-10-en-2-one
  • Δ9-Isooambrettolic acid lactone
  • 9-Hexadecenoic acid, 16-hydroxy-, o-lactone
  • Einecs 249-120-7
  • Fema no. 2555
  • Nsc 31697
  • Omega-6-hexadecenlactone (natural)
  • (E)-oxacycloheptadec-10-en-2-one
  • 16-HYDROXY-7-HEXADECENOIC ACID O-LACTONE
  • HEXADECEN-8-OLIDE
  • FEMA 2555
  • AMBRETTOLIDE 99% CAS 28645-51-4
  • Ambrettolide 1832003
  • 1-oxacycloheptadec-10-en-2-one
  • 28645-51-4