DIETHYL 4-CHLOROPHENYL MALONATE

Product Name: DIETHYL 4-CHLOROPHENYL MALONATE
CAS No.: 19677-37-3
Chemical Name: DIETHYL 4-CHLOROPHENYL MALONATE
Synonyms: RARECHEM AL BI 0611;2-(4-chlorophenyl)Malonic acid;DIETHYL 4-CHLOROPHENYL MALONATE;Diethyl (p-chlorophenyl)malonate;Diethyl 2-(4-chlorophenyl)Malonate;diethyl 2-(4-chlorophenyl)propanedioate;4-chlorophenyl 1-ethyl 2-ethylpropanedioate;2-(4-Chlorophenyl)-malonic acid diethylester;PROPANEDIOIC ACID, 2-(4-CHLOROPHENYL)-, 1,3-DIETHYL ESTER
CBNumber: CB7217034
Molecular Formula: C13H15ClO4
Formula Weight: 270.71
MOL File: 19677-37-3.mol

More

Less

DIETHYL 4-CHLOROPHENYL MALONATE Property

Boiling point:: 178-180 °C(Press: 15 Torr)
Density: 1.206±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 11.06±0.46(Predicted)
Appearance: Colorless to light yellow Liquid

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

More

Less

N-Bromosuccinimide Price

AK Scientific

Product number: 0138AB
Product name: Diethyl2-(4-chlorophenyl)malonate
Packaging: 250mg
Price: $157
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD155273
Product name: Diethyl 2-(4-chlorophenyl)malonate
Packaging: 2
Price: $400
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0142632
Product name: DIETHYL-4-CHLOROPHENYL MALONATE
Purity: 97.00%
Packaging: 1G
Price: $465.15
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD155273
Product name: Diethyl 2-(4-chlorophenyl)malonate
Packaging: 5G
Price: $500
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD155273
Product name: Diethyl 2-(4-chlorophenyl)malonate
Packaging: 10g
Price: $600
Updated: 2021/12/16

More

Less

DIETHYL 4-CHLOROPHENYL MALONATE Chemical Properties,Usage,Production

Synthesis

106-39-8

105-53-3

19677-37-3

The general procedure for the synthesis of diethyl 2-(4-chlorophenyl)malonate from 4-bromochlorobenzene and diethyl malonate is as follows: Example 6: Preparation of diethyl 2-(4-chlorophenyl)malonate by coupling reaction of 4-chlorobromobenzene with diethyl malonate 1. 191.5 mg (1 mmol) of 4-chlorobromobenzene and 160 mg (1 mmol) of diethyl malonate were dissolved in 5 mL of N,N-dimethylformamide (DMF), and 652 mg (2 mmol) of cesium carbonate was added to the reaction system under the protection of an inert gas, and the reaction mixture was stirred for 1 hour. 2. 17.9 mg (4 mol%) of HBPNS ligand and 9.0 mg (4 mol%) of palladium(II) acetate were added to the reaction system and the reaction mixture was subsequently heated to 80 °C and maintained at this temperature for 24 hours. 3. Upon completion of the reaction, post-treatment was performed: 5 mL of water and 10 mL of toluene were added to the reaction mixture, which was fully shaken and separated, and the lower aqueous phase was discarded. The organic phase was washed once more with 5 mL of water to remove residual DMF. 4. Finally, toluene was removed by rotary evaporator to give 230 mg (0.85 mmol, 85% yield) of the target product diethyl 2-(4-chlorophenyl)malonate.

References

[1] Patent: US2008/221350, 2008, A1. Location in patent: Page/Page column 5

DIETHYL 4-CHLOROPHENYL MALONATE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

DIETHYL 4-CHLOROPHENYL MALONATE Suppliers

China 30 Germany 3 India 1 United Kingdom 2 United States 4 Global 40

Tetranov Biopharm

Tel: 13526569071
Email: sales@leadmedpharm.com
Country: China
ProdList: 7892
Advantage: 64

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66028182 18626450290
Email: yftan@aikonchem.com
Country: China
ProdList: 16679
Advantage: 50

Chengdu YouSuo Biotechnology Limited

Tel: 13693449011
Fax: -
Email: 83948782@qq.com
Country: China
ProdList: 92
Advantage: 50

Zhengzhou Alfachem Co., Ltd.

Tel: 0371-53765687 18937137882
Fax: QQ:2885373884
Email: 2853979813@qq.com
Country: China
ProdList: 7991
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Nanjing KaiMubo Pharmaceutical Co., Ltd.

Tel: 025-66162170
Fax: 025-66162170
Country: China
ProdList: 7181
Advantage: 55

Chengdu Feibai Pharmaceutical Co., Ltd.

Tel: 028-84641798 18782128315
Email: 3302391190@qq.com
Country: China
ProdList: 9800
Advantage: 55

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30229
Advantage: 58

LEADMEDPHARM CO.,LTD

Tel: 13674959855 13674959855
Email: sales@synthontech.com
Country: China
ProdList: 3035
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44894
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44119
Advantage: 58

Beijing Stronger Science Co., Ltd.

Tel: 0531-88924771 15614660963
Email: elsa.hang@strongerscience.com
Country: China
ProdList: 10623
Advantage: 58

Hefei Mokai Pharmaceutical Technology Co., Ltd

Tel: 18130062233
Email: 3362556465@qq.com
Country: China
ProdList: 8100
Advantage: 58

Qi Qi hang Biotechnology Co., Ltd.

Tel: 15870833005
Email: 2232044025@qq.com
Country: China
ProdList: 8206
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39653
Advantage: 58

Pushan Industry (Shaanxi) Co., Ltd.

Tel: 029-81310890 13571859809
Email: info@pushanshiye.com
Country: China
ProdList: 9955
Advantage: 58

Shanghai Haohong Scientific Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 39845
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

https://hanhongsci.com/

Tel: 021-54306202 18917919676
Email: info@hanhongsci.com
Country: China
ProdList: 29995
Advantage: 58

Henan Vcommend Consultrading Co., Ltd.

Tel: 13393721940
Email: sales@vcommend.com
Country: China
ProdList: 9963
Advantage: 58

Wuhan WinYuanBei Trading Company

Tel: 86-13349903920 13349903920
Fax: -
Email: 869523959@qq.com
Country: China
ProdList: 9625
Advantage: 58

Tianjin Rongshen Chemical Co., Ltd

Tel: 18317763565; 18317763565
Email: 18317763565@163.com
Country: China
ProdList: 9516
Advantage: 58

Shanghai Hanhong Scientific Co., Ltd.

Tel: +undefined17612118332
Email: Lucky@hanhonggroup.com
Country: China
ProdList: 5844
Advantage: 58

DAYANG CHEM (HANGZHOU) CO.,LTD

Tel: +86-88938639 +86-17705817739
Email: info@dycnchem.com
Country: China
ProdList: 53899
Advantage: 58

HANGZHOU LEAP CHEM CO., LTD.

Tel: +86-571-87711850
Email: market18@leapchem.com
Country: China
ProdList: 43339
Advantage: 58

Hangzhou MolCore BioPharmatech Co.,Ltd.

Tel: +86-057181025280; +8617767106207
Fax: 0571-85806285
Email: sales@molcore.com
Country: China
ProdList: 49734
Advantage: 58

Rudong physical and chemical plants

Tel: --
Fax: --
Email: sales@frinton.com
Country: China
ProdList: 4687
Advantage: 80

19677-37-3, DIETHYL 4-CHLOROPHENYL MALONATERelated Search:

Sulfur trioxide Potassium hydroxide DIETHYL 2-(3,4-DICHLOROPHENYL)MALONATE DIETHYL 2,4-DICHLOROPHENYL MALONATE DIETHYL 4-CHLOROPHENYL MALONATE RARECHEM AL BI 0607 DIETHYL 2-(4-CHLORO-2-FLUOROPHENYL)MALONATE

DIETHYL 4-CHLOROPHENYL MALONATE

PROPANEDIOIC ACID, 2-(4-CHLOROPHENYL)-, 1,3-DIETHYL ESTER

Diethyl (p-chlorophenyl)malonate

2-(4-Chlorophenyl)-malonic acid diethylester

4-chlorophenyl 1-ethyl 2-ethylpropanedioate

2-(4-chlorophenyl)Malonic acid

Diethyl 2-(4-chlorophenyl)Malonate

RARECHEM AL BI 0611

diethyl 2-(4-chlorophenyl)propanedioate

19677-37-3

C13H15ClO4