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Cyclo(L-Pro-L-Trp-)

Product Name
Cyclo(L-Pro-L-Trp-)
CAS No.
38136-70-8
Chemical Name
Cyclo(L-Pro-L-Trp-)
Synonyms
Brevianamide F;Cyclo(-Trp-Pro);Cyclo(L-Trp-L-Pro-);Cyclo(L-Pro-L-Trp-);Eptifibatide Impurity 11;Cyclo-L-tryptophyl-L-proline;L-Prolyl-L-tryptophan anhydride;Trp-Pro-diketopiperazine Eptifibatide;(3S,8AS)-3-(1H-INDOL-3-YLMETHYL)HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE;(3S,8aα)-3β-(1H-Indole-3-ylmethyl)octahydropyrrolo[1,2-a]pyrazine-1,4-dione
CBNumber
CB72232479
Molecular Formula
C16H17N3O2
Formula Weight
283.33
MOL File
38136-70-8.mol
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Cyclo(L-Pro-L-Trp-) Property

Melting point:
165-167 °C
Boiling point:
633.2±48.0 °C(Predicted)
Density 
1.37±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
13.20±0.40(Predicted)
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML3432
Product name
Brevianamide F
Purity
≥98% (HPLC)
Packaging
5MG
Price
$63.2
Updated
2023/06/20
Sigma-Aldrich
Product number
SML3432
Product name
Brevianamide F
Purity
≥98% (HPLC)
Packaging
25MG
Price
$255
Updated
2023/06/20
Cayman Chemical
Product number
23493
Product name
Brevianamide F
Purity
≥98%
Packaging
5mg
Price
$50
Updated
2024/03/01
Cayman Chemical
Product number
23493
Product name
Brevianamide F
Purity
≥98%
Packaging
10mg
Price
$90
Updated
2024/03/01
Cayman Chemical
Product number
23493
Product name
Brevianamide F
Purity
≥98%
Packaging
25mg
Price
$176
Updated
2024/03/01
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Cyclo(L-Pro-L-Trp-) Chemical Properties,Usage,Production

Description

Brevianamide F is an alkaloid metabolite produced by various Streptomyces, Actinomycetes, and Aspergillus strains that has diverse biological activities. It inhibits growth of M. luteus and S. aureus in an inhibitory disc assay when used at a concentration of 30 μg/disc as well as the Bacille Calmette-Guerin M. bovis strain (MIC = 12.5 μg/ml). Brevianamide F has antifouling activity, inhibiting attachment of B. neritina larvae to PVC plates without inducing lethality (EC50 = 6.35 μg/ml; LC50 = >200 μg/ml in paint used to coat PVC plates).

Uses

Brevianamide F is used in the preparation, reactions, medicinal and cheical propreties of diketopiperazines as bioactive natural products. Acts as a reagent in the total synthesis and antitumor activity in vitro of glioperazine C and its derivatives, synthesis and biological evaluation of a post-synthetically trp-based diketopiperazine and it’s antitumor structure-activity relationship.

Definition

ChEBI: A pyrrolopyrazine that is hexahydropyrrolo[1,2-a]pyrazine-1,4-dione bearing an indol-3-ylmethyl substituent at position 3 (the 3S,8aS-diastereomer, obtained by formal cyclocondensation of L-tr ptophan and L-proline).

Cyclo(L-Pro-L-Trp-) Preparation Products And Raw materials

Raw materials

Preparation Products

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Cyclo(L-Pro-L-Trp-) Suppliers

China 64 India 2 United States 8 Global 74
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View Lastest Price from Cyclo(L-Pro-L-Trp-) manufacturers

Career Henan Chemical Co
Product
Cyclo(L-Pro-L-Trp-) 38136-70-8
Price
US $1.00/ASSAYS
Min. Order
1ASSAYS
Purity
95%~99%
Supply Ability
per week:100kg
Release date
2019-09-05

38136-70-8, Cyclo(L-Pro-L-Trp-)Related Search:

L-Aspartic acid, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-, (1→3')-disulfide with L-tryptophyl-L-prolyl-L-cysteinamide (9CI) Eptifibatide impurity 3/Deamidated Eptifibatide Impurity/(3R,11S,17S,20S,25aS)-20-((1H-indol-3-yl)Methyl)-17-(carboxymethyl)-11-(4-guanidinobutyl)-1,9,12,15,18,21-hexaoxodocosahydro-1H-pyrrolo[2,1-g][1,2,5,8,11,14,17,20]dithiahexaazacyclotricosine-3-carbo L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-, bimol. cyclic (1→1'),(6→6')-bis(disulfide) N-[2-(Phenylmethyl)phenyl]-2-chloroacetamide Acetamide, 2-methoxy-N-[2-(phenylmethyl)phenyl]- Methanone, (2-aminophenyl)phenyl-, hydrazone, (Z)- L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1→7)-disulfide (9CI) Benzamide, N-[(6,11-dihydro-5H-dibenz[b,e]azepin-6-yl)methyl]-2-(hydroxymethyl)- 7-Bromo Epinastine Eptifibatide non cyclic impurity 3'-Hydroxyacetophenone 6-Chloromethylmorphanthridine Acetamide, 2-(1-methylethoxy)-N-[2-(phenylmethyl)phenyl]-

  • (3S)-2,3,6,7,8,8aα-Hexahydro-3β-(1H-indol-3-ylmethyl)pyrrolo[1,2-a]pyrazine-1,4-dione
  • (3S,8aα)-3β-(1H-Indole-3-ylmethyl)octahydropyrrolo[1,2-a]pyrazine-1,4-dione
  • Brevianamide F
  • Cyclo(L-Pro-L-Trp-)
  • Cyclo(L-Trp-L-Pro-)
  • (3S,8AS)-3-(1H-INDOL-3-YLMETHYL)HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE
  • Cyclo(-Trp-Pro)
  • Cyclo-L-tryptophyl-L-proline
  • Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(1H-indol-3-ylmethyl)-, (3S,8aS)-
  • Trp-Pro-diketopiperazine Eptifibatide
  • Bacterial,Inhibitor,PI3K,Brevianamide F,antibacterial,PI3Kα,inhibit,Phosphoinositide 3-kinase,mycotoxin
  • Eptifibatide Impurity 11
  • L-Prolyl-L-tryptophan anhydride
  • 38136-70-8