METHYL 3-(TRIFLUOROMETHYL)PHENYLACETATE
- Product Name
- METHYL 3-(TRIFLUOROMETHYL)PHENYLACETATE
- CAS No.
- 62451-84-7
- Chemical Name
- METHYL 3-(TRIFLUOROMETHYL)PHENYLACETATE
- Synonyms
- Methyl 2-(3-(;AURORA KA-6005;Methyl 2-(3-(trifluoromethyl);METHYL 3-(TRIFLUOROMETHYL)PHENYLACETATE;Methyle3-(trifluoromethyl)phenylacetate;Methyl3-(trifluoromethyl)phenylacetate,95%;Methyl 2-[3-(trifluoromethyl)phenyl]acetate;Methyl 3-(trifluoromethyl)phenylacetate,97%;Methyl 3-(trifluoromethyl)phenylacetate 97%;(3-TRIFLUOROMETHYLPHENYL) ACETIC ACID METHYL ESTER
- CBNumber
- CB7225114
- Molecular Formula
- C10H9F3O2
- Formula Weight
- 218.17
- MOL File
- 62451-84-7.mol
METHYL 3-(TRIFLUOROMETHYL)PHENYLACETATE Property
- Boiling point:
- 211℃
- Density
- 1.24
- refractive index
- 1.45-1.452
- storage temp.
- Sealed in dry,Room Temperature
- form
- Liquid
- color
- Clear colorless
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- EME00055
- Product name
- Methyl 2-[3-(trifluoromethyl)phenyl]acetate
- Packaging
- 1G
- Price
- $36.7
- Updated
- 2025/07/31
- Product number
- M332153
- Product name
- Methyl3-(trifluoromethyl)phenylacetate
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- 9411AB
- Product name
- Methyl2-(3-(trifluoromethyl)phenyl)acetate
- Packaging
- 1g
- Price
- $67
- Updated
- 2021/12/16
- Product number
- 9411AB
- Product name
- Methyl2-(3-(trifluoromethyl)phenyl)acetate
- Packaging
- 5g
- Price
- $99
- Updated
- 2021/12/16
- Product number
- PC4391
- Product name
- Methyl3-(trifluoromethyl)phenylacetate
- Packaging
- 25g
- Price
- $135
- Updated
- 2021/12/16
METHYL 3-(TRIFLUOROMETHYL)PHENYLACETATE Chemical Properties,Usage,Production
Chemical Properties
clear colorless liquid
Synthesis
67-56-1
351-35-9
62451-84-7
Concentrated sulfuric acid (50 mL) was added slowly to a solution of methanol (1200 mL) of m-trifluoromethylphenylacetic acid (1.0 mol). The reaction mixture was heated to reflux and the reaction was stirred overnight. Upon completion of the reaction, the reaction solution was concentrated to dryness under reduced pressure. Water (600 mL) was added to the residue and extracted with ethyl acetate (3 x 400 mL). The organic layers were combined and washed with water until neutral. The organic layer was dried with anhydrous sodium sulfate, filtered and concentrated. The crude product was purified by column chromatography (eluent: ethyl acetate/petroleum ether=1:20) to afford methyl 3-trifluoromethylphenylacetate (108 g, 100% yield) as a yellow oil.
References
[1] Bioorganic and Medicinal Chemistry, 2003, vol. 11, # 13, p. 2843 - 2866
[2] Patent: US2005/234046, 2005, A1. Location in patent: Page/Page column 97
[3] Helvetica Chimica Acta, 1971, vol. 54, p. 868 - 897
[4] Tetrahedron Letters, 2018, vol. 59, # 22, p. 2161 - 2166
[5] Patent: US2479295, 1946,
METHYL 3-(TRIFLUOROMETHYL)PHENYLACETATE Preparation Products And Raw materials
Raw materials
Preparation Products
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