CALMIDAZOLIUM CHLORIDE

Product Name: CALMIDAZOLIUM CHLORIDE
CAS No.: 94724-12-6
Chemical Name: CALMIDAZOLIUM CHLORIDE
Synonyms: R 24571;CALMIDAZOLIUM;COMPOUND 48/80;COMPOUND R24571;R 24571 CHLORIDE;CALMIDAZOLIUM CHLORIDE;CALMODULIN INHIBITOR R 24571;COMPOUND 48/80 TRIHYDROCHLORIDE;Poly-p-methoxyphenethylmethylamine;Compound 48/80 trihydrochloride, G protein activator
CBNumber: CB7231629
Molecular Formula: C32H45N3O3
Formula Weight: 519.72
MOL File: 94724-12-6.mol

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CALMIDAZOLIUM CHLORIDE Property

Boiling point:: 630.9±50.0 °C(Predicted)
Density: 1.050±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: H₂O: 50 mg/mL
pka: 10.81±0.10(Predicted)
form: solid
color: white

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Safety

Hazard Codes: T
Risk Statements: 23/24/25
Safety Statements: 22-24/25-45-36/37
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
F: 3-8-10

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Hazard and Precautionary Statements (GHS)

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CALMIDAZOLIUM CHLORIDE Chemical Properties,Usage,Production

Uses

Compound 48/80 (Poly-p-methoxyphenethylmethylamine) is widely used in animal and tissue models as a "selective" mast cell activator. Compound 48/80 acts at the mast cell membrane to stimulate trimeric G-proteins and induces degranulation via phospholipase C and D pathways[1][2].

References

[1] Schemann M, et al. The mast cell degranulator compound 48/80 directly activates neurons. PLoS One. 2012;7(12):e52104. DOI:10.1371/journal.pone.0052104
[2] Wang YH, Taché Y, Harris AG, Kreutner W, Daly AF, Wei JY. Desloratadine prevents compound 48/80-induced mast cell degranulation: visualization using a vital fluorescent dye technique. Allergy. 2005;60(1):117-124. DOI:10.1111/j.1398-9995.2004.00641.x
[3] Darzynkiewicz Z, Carter S. Compound 48/80 impairs cytokinesis in murine leukemic cells. J Cell Physiol. 1984;119(1):1-6. DOI:10.1002/jcp.1041190102

CALMIDAZOLIUM CHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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CALMIDAZOLIUM CHLORIDE Suppliers

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94724-12-6, CALMIDAZOLIUM CHLORIDERelated Search:

Bovine albumin CALMIDAZOLIUM CHLORIDE,CALMIDAZOLIUM,CALMIDAZOLIUM CHLORIDE

COMPOUND 48/80

COMPOUND 48/80 TRIHYDROCHLORIDE

COMPOUND R24571

R 24571

R 24571 CHLORIDE

CALMODULIN INHIBITOR R 24571

CALMIDAZOLIUM

CALMIDAZOLIUM CHLORIDE

1-[Bis(4-Chlorophenyl)methyl]-3-[2-(2,4-dichlorophenyl)-2-(2,4-dichlorobenzyloxy)ethyl]-1H-imidazolium chloride

1-[BIS-(4-CHLOROPHENYL)METHYL]-3-[2-(2,4-DICHLOROPHENYL)-2-[(2,4-DICHLOROPHENYL)METHOXY]-ETHYL]-1H-IMIDAZOLIUM CHLORIDE

1-[BIS(4-CHLOROPHENYL)METHYL]-3-[2,4-DICHLORO-BETA-(2,4-DICHLOROBENZYLOXY)PHENETHYL]IMIDAZOLIUM CHLORIDE

1-[BIS(P-CHLOROPHENYL)METHYL]-3-[2-(2,4-DICHLORO-BETA-(2,4-DICHLOROBENZYLOXY)PHENETHYL)]IMIDAZOLIUM CHLORIDE

1-[BIS(P-CHLOROPHENYL)METHYL]-3-[2,4-DICHLORO-BETA-(2,4 DICHLOROBENZYLOXY) PHENETHYL]-IMIDAZOLIUM CHLORIDE

[1-BIS-P-CHLOROPHENYL) METHYL]-3-[2,4-DICHLORO-BETA-(2,4-DICHLOROBENZYLOXY) PHENYL]-IMIDAZOLIUM CHLORIDE

Benzeneethanamine, 4-methoxy-3,5-bis[[2-methoxy-5-[2-(methylamino)ethyl]phenyl]methyl]-N-methyl-

Poly-p-methoxyphenethylmethylamine

Compound 48/80 trihydrochloride, G protein activator

94724-12-6

C32H45N3O3

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