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CALMIDAZOLIUM CHLORIDE

Product Name
CALMIDAZOLIUM CHLORIDE
CAS No.
94724-12-6
Chemical Name
CALMIDAZOLIUM CHLORIDE
Synonyms
R 24571;CALMIDAZOLIUM;COMPOUND 48/80;COMPOUND R24571;R 24571 CHLORIDE;CALMIDAZOLIUM CHLORIDE;CALMODULIN INHIBITOR R 24571;COMPOUND 48/80 TRIHYDROCHLORIDE;Poly-p-methoxyphenethylmethylamine;Compound 48/80 trihydrochloride, G protein activator
CBNumber
CB7231629
Molecular Formula
C32H45N3O3
Formula Weight
519.72
MOL File
94724-12-6.mol
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CALMIDAZOLIUM CHLORIDE Property

Boiling point:
630.9±50.0 °C(Predicted)
Density 
1.050±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
H2O: 50 mg/mL
pka
10.81±0.10(Predicted)
form 
solid
color 
white
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Safety

Hazard Codes 
T
Risk Statements 
23/24/25
Safety Statements 
22-24/25-45-36/37
RIDADR 
UN 2811 6.1/PG 2
WGK Germany 
3
F 
3-8-10
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Hazard and Precautionary Statements (GHS)

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CALMIDAZOLIUM CHLORIDE Chemical Properties,Usage,Production

Uses

Compound 48/80 (Poly-p-methoxyphenethylmethylamine) is widely used in animal and tissue models as a "selective" mast cell activator. Compound 48/80 acts at the mast cell membrane to stimulate trimeric G-proteins and induces degranulation via phospholipase C and D pathways[1][2].

References

[1] Schemann M, et al. The mast cell degranulator compound 48/80 directly activates neurons. PLoS One. 2012;7(12):e52104. DOI:10.1371/journal.pone.0052104
[2] Wang YH, Taché Y, Harris AG, Kreutner W, Daly AF, Wei JY. Desloratadine prevents compound 48/80-induced mast cell degranulation: visualization using a vital fluorescent dye technique. Allergy. 2005;60(1):117-124. DOI:10.1111/j.1398-9995.2004.00641.x
[3] Darzynkiewicz Z, Carter S. Compound 48/80 impairs cytokinesis in murine leukemic cells. J Cell Physiol. 1984;119(1):1-6. DOI:10.1002/jcp.1041190102

CALMIDAZOLIUM CHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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CALMIDAZOLIUM CHLORIDE Suppliers

China 30 Germany 1 Japan 1 Switzerland 2 United Kingdom 1 United States 9 Global 44
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71

94724-12-6, CALMIDAZOLIUM CHLORIDERelated Search:

Bovine albumin CALMIDAZOLIUM CHLORIDE,CALMIDAZOLIUM,CALMIDAZOLIUM CHLORIDE

  • COMPOUND 48/80
  • COMPOUND 48/80 TRIHYDROCHLORIDE
  • COMPOUND R24571
  • R 24571
  • R 24571 CHLORIDE
  • CALMODULIN INHIBITOR R 24571
  • CALMIDAZOLIUM
  • CALMIDAZOLIUM CHLORIDE
  • 1-[Bis(4-Chlorophenyl)methyl]-3-[2-(2,4-dichlorophenyl)-2-(2,4-dichlorobenzyloxy)ethyl]-1H-imidazolium chloride
  • 1-[BIS-(4-CHLOROPHENYL)METHYL]-3-[2-(2,4-DICHLOROPHENYL)-2-[(2,4-DICHLOROPHENYL)METHOXY]-ETHYL]-1H-IMIDAZOLIUM CHLORIDE
  • 1-[BIS(4-CHLOROPHENYL)METHYL]-3-[2,4-DICHLORO-BETA-(2,4-DICHLOROBENZYLOXY)PHENETHYL]IMIDAZOLIUM CHLORIDE
  • 1-[BIS(P-CHLOROPHENYL)METHYL]-3-[2-(2,4-DICHLORO-BETA-(2,4-DICHLOROBENZYLOXY)PHENETHYL)]IMIDAZOLIUM CHLORIDE
  • 1-[BIS(P-CHLOROPHENYL)METHYL]-3-[2,4-DICHLORO-BETA-(2,4 DICHLOROBENZYLOXY) PHENETHYL]-IMIDAZOLIUM CHLORIDE
  • [1-BIS-P-CHLOROPHENYL) METHYL]-3-[2,4-DICHLORO-BETA-(2,4-DICHLOROBENZYLOXY) PHENYL]-IMIDAZOLIUM CHLORIDE
  • Benzeneethanamine, 4-methoxy-3,5-bis[[2-methoxy-5-[2-(methylamino)ethyl]phenyl]methyl]-N-methyl-
  • Poly-p-methoxyphenethylmethylamine
  • Compound 48/80 trihydrochloride, G protein activator
  • 94724-12-6
  • C32H45N3O3
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Calcium Antagonists
  • BioChemical
  • Biochemicals and Reagents
  • Antibiotics
  • Antibiotics A-F
  • Antibiotics A to Z
  • Other
  • Intracellular Calcium Signaling
  • Enzyme Inhibitors by Type
  • Enzyme Inhibitors
  • Enzymes, Inhibitors, and Substrates
  • Antibiotics A-FEnzyme Inhibitors by Enzyme
  • Phospholipase CLipids in Cell Signaling
  • Phospholipase Inhibitors
  • Antibiotics
  • Antibiotics A to
  • P to
  • Phospholipid Metabolism