5,10,15,20-TETRAKIS(4-HYDROXYPHENYL)-21H,23H-PORPHINE
- Product Name
- 5,10,15,20-TETRAKIS(4-HYDROXYPHENYL)-21H,23H-PORPHINE
- CAS No.
- 51094-17-8
- Chemical Name
- 5,10,15,20-TETRAKIS(4-HYDROXYPHENYL)-21H,23H-PORPHINE
- Synonyms
- RARECHEM AS SA 0037;MESO-TETRA(P-HYDROXYPHENYL)PORPHINE;meso-Tetrakis(4-hydroxyphenyl)porphyrin;5,10,15,20-tetrakis(4-hydroxyphenyl)-21H;5,10,15,20-tetra(4-hydroxyphenyl)porphyrin;5,10,15,20-Tetrakis(4-hydroxyphenyl)porphin;5,10,15,20-Tetrakis(4-hydroxyphenyl)porphyrin;5,10,15,20-TETRAKIS(4-HYDROXYPHENYL)-21H,23H-PORPHINE;5,10,15,20-TETRAKIS-(4-HYDROXYPHENYL)-21,23H-PORPHYRIN;5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphyrin
- CBNumber
- CB7234897
- Molecular Formula
- C44H30N4O4
- Formula Weight
- 678.73
- MOL File
- 51094-17-8.mol
5,10,15,20-TETRAKIS(4-HYDROXYPHENYL)-21H,23H-PORPHINE Property
- Melting point:
- >300 °C(lit.)
- Density
- 1.401±0.06 g/cm3(Predicted)
- storage temp.
- room temp
- form
- powder to crystal
- color
- Gray to Dark purple to Black
- λmax
- 421 nm
- ε(extinction coefficient)
- ≥285000 at 417-423nm in methanol at 0.001g/L
- InChIKey
- VFHDWGAEEDVVPD-LWQDQPMZSA-N
- SMILES
- C1(C2=CC=C(O)C=C2)=C2N=C(C(C3=CC=C(O)C=C3)=C3NC(=C(C4=CC=C(O)C=C4)C4=NC(=C(C5=CC=C(O)C=C5)C5NC1=CC=5)C=C4)C=C3)C=C2 |c:20,t:8,23,35|
Safety
- Hazard Codes
- C
- Risk Statements
- 34-37
- Safety Statements
- 26-36/37/39-45
- RIDADR
- UN 3263 8/PG 3
- WGK Germany
- 1
- HS Code
- 2934.30.5000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 477567
- Product name
- 5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphine
- Purity
- Dye content 95%
- Packaging
- 250mg
- Price
- $107
- Updated
- 2025/07/31
- Product number
- 477567
- Product name
- 5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphine
- Purity
- Dye content 95%
- Packaging
- 1g
- Price
- $312
- Updated
- 2025/07/31
- Product number
- T1497
- Product name
- 5,10,15,20-Tetrakis(4-hydroxyphenyl)porphyrin
- Purity
- >95.0%(HPLC)
- Packaging
- 100mg
- Price
- $76
- Updated
- 2025/07/31
- Product number
- T310525
- Product name
- meso-Tetra(p-hydroxyphenyl)porphine
- Packaging
- 250mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- T310525
- Product name
- meso-Tetra(p-hydroxyphenyl)porphine
- Packaging
- 500mg
- Price
- $115
- Updated
- 2021/12/16
5,10,15,20-TETRAKIS(4-HYDROXYPHENYL)-21H,23H-PORPHINE Chemical Properties,Usage,Production
Description
5,10,15,20-(tetra-4-hydroxyphenyl)porphyrin is a porphyrin derivative used for detection of water-soluble vitamins by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry.
Uses
meso-Tetra(p-hydroxyphenyl)porphine is a porphyrin derivative used for research.
Synthesis
109-97-7
123-08-0
51094-17-8
6.1 g of p-hydroxybenzaldehyde was dissolved in 110 mL of propionic acid, 6 mL of dimethyl sulfoxide (DMSO) was added, the mixture was mechanically stirred and heated to 128°C. Freshly distilled 3.5 mL of pyrrole was dissolved in 10 mL of propionic acid and slowly added dropwise at a rate of 1 drop per second to the above reaction mixture. The temperature of the reaction system was then raised to 141 °C and the reaction was refluxed for 2 hours. Upon completion of the reaction, hot filtration was performed and the filter cake was washed twice with propionic acid to obtain a blue solid 5,10,15,20-tetrakis(4-hydroxyphenyl)porphyrin crude product. 10 g of the dried crude product was placed in a 100 mL round-bottomed flask, 20 mL of anhydrous ethanol was added and heated to reflux for 15 minutes before continuing to heat for 1.5 hours. The reaction solution was cooled in an ice bath for 1.5 h. The reaction solution was filtered and washed twice with ethanol to give 0.6172 g of 5,10,15,20-tetrakis(4-hydroxyphenyl)porphyrin in 7.27% yield. Finally, the purified product was purified by silica gel column chromatography (200 mesh) using acetone as eluent.
References
[1] Patent: CN105085536, 2018, B. Location in patent: Paragraph 0060; 0117-0122
[2] Journal of the American Chemical Society, 2013, vol. 135, # 49, p. 18513 - 18519
[3] Macromolecular Bioscience, 2013, vol. 13, # 6, p. 808 - 816
[4] Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals, 2001, vol. 364, p. 611 - 623
[5] Tetrahedron Letters, 2007, vol. 48, # 41, p. 7287 - 7290
5,10,15,20-TETRAKIS(4-HYDROXYPHENYL)-21H,23H-PORPHINE Preparation Products And Raw materials
Raw materials
Preparation Products
5,10,15,20-TETRAKIS(4-HYDROXYPHENYL)-21H,23H-PORPHINE Suppliers
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View Lastest Price from 5,10,15,20-TETRAKIS(4-HYDROXYPHENYL)-21H,23H-PORPHINE manufacturers
- Product
- 5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphine 51094-17-8
- Price
- US $18.00-48.00/KG
- Min. Order
- 0.01KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2025-06-19
- Product
- 5,10,15,20-Tetrakis(4-hydroxyphenyl)porphyrin 51094-17-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-12-25