ChemicalBook > CAS DataBase List > 1,3-Dioxo-1H-benzo[de]isoquinoline-2(3H)-acetic acid sodium salt
1,3-Dioxo-1H-benzo[de]isoquinoline-2(3H)-acetic acid sodium salt
- Product Name
- 1,3-Dioxo-1H-benzo[de]isoquinoline-2(3H)-acetic acid sodium salt
- CAS No.
- 51876-97-2
- Chemical Name
- 1,3-Dioxo-1H-benzo[de]isoquinoline-2(3H)-acetic acid sodium salt
- Synonyms
- AY-22284A;Alrestatin sodium;Alrestatine sodium;sodium,2-(1,3-dioxobenzo[de]isoquinolin-2-yl)acetate;1,3-Dioxo-1H-benz[de]isoquinoline-2(3H)-acetic acid sodium salt;1,3-Dioxo-1H-benzo[de]isoquinoline-2(3H)-acetic acid sodium salt
- CBNumber
- CB72395871
- Formula Weight
- 0
- MOL File
- 51876-97-2.mol
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- CHM1037109
- Product name
- SODIUM 2-(1,3-DIOXOBENZO[DE]ISOQUINOLIN-2-YL)ACETATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $499.32
- Updated
- 2021/12/16
Crysdot
- Product number
- CD31001656
- Product name
- Alrestatinsodium
- Purity
- 98+%
- Packaging
- 5mg
- Price
- $55
- Updated
- 2021/12/16
CSNpharm
- Product number
- CSN18314
- Product name
- AlrestatinSodium
- Packaging
- 5mg
- Price
- $77
- Updated
- 2021/12/16
Crysdot
- Product number
- CD31001656
- Product name
- Alrestatinsodium
- Purity
- 98+%
- Packaging
- 10mg
- Price
- $83
- Updated
- 2021/12/16
CSNpharm
- Product number
- CSN18314
- Product name
- AlrestatinSodium
- Packaging
- 10mg
- Price
- $115
- Updated
- 2021/12/16
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1,3-Dioxo-1H-benzo[de]isoquinoline-2(3H)-acetic acid sodium salt Chemical Properties,Usage,Production
Originator
Alrestatin,BIOMOL
Uses
Enzyme inhibitor (aldose reductase).
Manufacturing Process
1,3-Dioxo-1H-benz[de]isoquinoline-2(3H)-acetic acid:
1,8-Naphthalic acid anhydride (110 g, 0.556 mole), glycine (48 g, 0.64 mole)
and dimethylformamide (750 ml) are heated and stirred at reflux for 2 hr. The
homogeneous dark solution is cooled to about 100°C and 750 ml of hot water
is added slowly to the stirred solution. The reaction mixture is cooled and
allowed to stand in a refrigerator for 16 hr. The precipitate is collected and
recrystallized from ethanol, using decolorizing charcoal, to give the title
compound, MP: 271°-272°C.
In practice it is usually used as sodium salt.
Therapeutic Function
Aldose reductase inhibitor
1,3-Dioxo-1H-benzo[de]isoquinoline-2(3H)-acetic acid sodium salt Preparation Products And Raw materials
Raw materials
Preparation Products
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1,3-Dioxo-1H-benzo[de]isoquinoline-2(3H)-acetic acid sodium salt Suppliers
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