6-METHYL-2,2'-BIPYRIDINE
- Product Name
- 6-METHYL-2,2'-BIPYRIDINE
- CAS No.
- 56100-22-2
- Chemical Name
- 6-METHYL-2,2'-BIPYRIDINE
- Synonyms
- 6-METHYL-2,2'-DIPYRIDYL;6-Methyl-2,2'-Bipyridine;6-Methyl-2,2 '- Dipyridine;2,2'-Bipyridine, 6-Methyl-;6-Methyl-2,2'-dipyridyl 97%;6-methyl-2-(2-pyridyl)pyridine;2-methyl-6-(pyridin-2-yl)pyridine
- CBNumber
- CB7241622
- Molecular Formula
- C11H10N2
- Formula Weight
- 170.21
- MOL File
- 56100-22-2.mol
6-METHYL-2,2'-BIPYRIDINE Property
- Boiling point:
- 117-119 °C0.1 mm Hg(lit.)
- Density
- 1.09 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.607(lit.)
- Flash point:
- >230 °F
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 4.82±0.10(Predicted)
- Appearance
- Yellow to brown Solid-Liquid Mixture
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 0933AQ
- Product name
- 6-Methyl-2,2′-dipyridyl
- Packaging
- 1g
- Price
- $292
- Updated
- 2021/12/16
- Product number
- CHM0160213
- Product name
- 6-METHYL-2,2'-DIPYRIDYL
- Purity
- 97.00%
- Packaging
- 1G
- Price
- $773.73
- Updated
- 2021/12/16
- Product number
- A272877
- Product name
- 6-Methyl-2,2'-bipyridine
- Purity
- 98%
- Packaging
- 5g
- Price
- $800
- Updated
- 2021/12/16
- Product number
- CM171956
- Product name
- 2-methyl-6-pyridin-2-ylpyridine
- Purity
- 95+%
- Packaging
- 5g
- Price
- $812
- Updated
- 2021/12/16
- Product number
- 56100222
- Product name
- 6-Methyl-2,2'-bipyridine
- Packaging
- 5g
- Price
- $529.2
- Updated
- 2021/12/16
6-METHYL-2,2'-BIPYRIDINE Chemical Properties,Usage,Production
Synthesis
366-18-7
917-54-4
56100-22-2
A tetrahydrofuran (26 mL) solution of methyl lithium (1.3 M, 33.80 mmol) was slowly added dropwise to an ethyl ether (100 mL) solution of 2,2'-bipyridine (5.30 g, 34.00 mmol) at 0°C and under nitrogen protection. The reaction mixture was stirred at this temperature for 2 hours and then refluxed at elevated temperature for 3 hours. When the reaction solution was cooled to room temperature, the reaction was quenched by the addition of water (10 mL). The organic phase was separated and the aqueous phase was extracted with ether three times. The organic phases were combined and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure to give an orange colored oil. This oily material was dissolved in acetone solution saturated with potassium permanganate (300 mL) and stirred at room temperature for 1 hour for oxidation reaction. The filtrate was filtered and concentrated to remove the acetone. The residue was purified by vacuum distillation to afford the colorless oily target product 6-methyl-2,2'-bipyridine (3.73 g, 63.8% yield). The structure of the product was confirmed by nuclear magnetic resonance hydrogen spectroscopy (1H NMR, 400MHz, CDCl3), carbon spectroscopy (13C NMR, 100MHz, CDCl3) and electrospray ionization mass spectrometry (ESI-MS): 1H NMR δ 8.65 (s, 1H), 8.38 (d, J = 8.0 Hz, 1H), 8.15 (d, J = 7.9 Hz, 1H), 7.72-7.82 (d, J = 7.9 Hz, 1H), 8.15 (d, J = 7.9 Hz, 1H) 7.72-7.82 (m, 1H), 7.66 (d, J = 7.7 Hz, 1H), 7.21-7.30 (m, 1H), 7.13 (d, J = 7.7 Hz, 1H), 2.61 (s, 3H); 13C NMR δ 157.7, 156.3, 155.4, 149.0, 136.9, 136.7, 123.6, 123.2, 121.02, 117.9, 24.5; ESI-MS m/z: [M+H]+ measured value 171.61 (calculated value 171.22).
References
[1] Angewandte Chemie - International Edition, 2014, vol. 53, # 23, p. 5872 - 5876
[2] Dyes and Pigments, 2016, vol. 128, p. 33 - 40
[3] Patent: CN105669689, 2016, A. Location in patent: Paragraph 0032
[4] Angewandte Chemie - International Edition, 2016, vol. 55, # 37, p. 11207 - 11211
[5] Angew. Chem., 2016, vol. 128, # 37, p. 11373 - 11377,5
6-METHYL-2,2'-BIPYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-METHYL-2,2'-BIPYRIDINE manufacturers
- Product
- 6-METHYL-2,2'-BIPYRIDINE 56100-22-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2019-08-07