ChemicalBook > CAS DataBase List > H-D-PRO-PHE-ARG-PNA 2 HCL
H-D-PRO-PHE-ARG-PNA 2 HCL
- Product Name
- H-D-PRO-PHE-ARG-PNA 2 HCL
- CAS No.
- 62354-56-7
- Chemical Name
- H-D-PRO-PHE-ARG-PNA 2 HCL
- Synonyms
- pFR-pNA;H-D-PRO-PHE-ARG-PNA 2 HCL;H-D-Pro-Phe-Arg-pNA ·2HCI;S-2302 (Chromogenic substrate);D-Pro-Phe-Arg-pNA (hydrochloride);D-pro-phe-arg P-nitroanilide*dihydrochloride;L-Argininamide,D-prolyl-L-phenylalanyl-N-(4-nitrophenyl)-,dihydrochloride
- CBNumber
- CB7243631
- Molecular Formula
- C26H36Cl2N8O5
- Formula Weight
- 611.52
- MOL File
- 62354-56-7.mol
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H-D-PRO-PHE-ARG-PNA 2 HCL Property
- storage temp.
- -15°C
- solubility
- DMF: 10 mg/ml; PBS (pH 7.2): 5 mg/ml
- form
- A crystalline solid
- Sequence
- {d-Pro}-Phe-Arg-{pNA}
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Safety
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-33-36/37/38-63
- Safety Statements
- 28-36/37-45
- WGK Germany
- 3
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 27569
- Product name
- D-Pro-Phe-Arg-pNA (hydrochloride)
- Packaging
- 25mg
- Price
- $81
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 27569
- Product name
- D-Pro-Phe-Arg-pNA (hydrochloride)
- Packaging
- 250mg
- Price
- $632
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 27569
- Product name
- D-Pro-Phe-Arg-pNA (hydrochloride)
- Packaging
- 50mg
- Price
- $152
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 27569
- Product name
- D-Pro-Phe-Arg-pNA (hydrochloride)
- Packaging
- 100mg
- Price
- $286
- Updated
- 2024/03/01
Chem-Impex
- Product number
- 11673
- Product name
- H-D-Pro-Phe-Arg-pNA·2HCl
- Packaging
- 5MG
- Price
- $335.46
- Updated
- 2021/12/16
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H-D-PRO-PHE-ARG-PNA 2 HCL Chemical Properties,Usage,Production
Description
D-Pro-Phe-Arg-pNA is a colorimetric substrate for plasma kallikrein. Plasma kallikrein preferentially binds to and cleaves the D-Pro-Phe-Arg (PFR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of plasma kallikrein activity.
Uses
D-Pro-Phe-Arg-pNA hydrochloride is the substrate for thrombin-like enzyme, with Km of 50.7 μM[1].
References
[1] Magalh?es HP, et al., Mechanism of action and determination of the best substrate for a thrombin-like enzyme from Lachesis muta muta venom by regression analysis of the kinetic parameters determined with peptidyl p-nitroanilide substrates. Toxicon. 2006 Mar 15;47(4):453-8. DOI:10.1016/j.toxicon.2006.01.001
H-D-PRO-PHE-ARG-PNA 2 HCL Preparation Products And Raw materials
Raw materials
Preparation Products
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H-D-PRO-PHE-ARG-PNA 2 HCL Suppliers
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