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GLY-ARG P-NITROANILIDE DIHYDROCHLORIDE

Product Name
GLY-ARG P-NITROANILIDE DIHYDROCHLORIDE
CAS No.
125455-61-0
Chemical Name
GLY-ARG P-NITROANILIDE DIHYDROCHLORIDE
Synonyms
GR-pNA GR;Gly-Arg-4-NA;H-GLY-ARG-PNA 2HCL;H-Gly-Arg-Pna dihydrochloride;GLY-ARG-4-NA;GR-PNAGR; P-NITROANILIDE;GLY-ARG P-NITROANILIDE DIHYDROCHLORIDE;Gly-Arg-p-nitroanilide dihydrochloride unokinase and plasmin substrate
CBNumber
CB3682144
Molecular Formula
C14H23Cl2N7O4
Formula Weight
424.28
MOL File
125455-61-0.mol
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GLY-ARG P-NITROANILIDE DIHYDROCHLORIDE Property

storage temp. 
−20°C
solubility 
DMF: 20mg/mL; DMSO: 3mg/mL; PBS (pH 7.2): 3mg/mL
form 
A solid
InChIKey
UMNMBKCWESYUMR-LCJJWKFENA-N
SMILES
C1(C=CC([N+]([O-])=O)=CC=1)NC(=O)[C@@H](NC(=O)CN)CCCNC(=N)N.Cl.Cl |&1:12,r|
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
27705
Product name
H-Gly-Arg-pNA (hydrochloride)
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
27705
Product name
H-Gly-Arg-pNA (hydrochloride)
Packaging
25mg
Price
$618
Updated
2024/03/01
Cayman Chemical
Product number
27705
Product name
H-Gly-Arg-pNA (hydrochloride)
Packaging
5mg
Price
$161
Updated
2024/03/01
Cayman Chemical
Product number
27705
Product name
H-Gly-Arg-pNA (hydrochloride)
Packaging
10mg
Price
$283
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
AAA0004309
Product name
GLY-ARG-P-NITROANILIDE DIHYDROCHLORIDE
Purity
95.00%
Packaging
25MG
Price
$719.52
Updated
2021/12/16
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GLY-ARG P-NITROANILIDE DIHYDROCHLORIDE Chemical Properties,Usage,Production

Description

H-Gly-Arg-pNA is a colorimetric substrate for thrombin. Thrombin preferentially binds to and cleaves the Gly-Arg (GR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of thrombin activity.

Uses

H-Gly-Arg-pNA hydrochloride (GR-pNA hydrochloride) is a colorimetric substrate for thrombin. H-Gly-Arg-pNA is preferentially bound by thrombin and cleaves the Gly-Arg (GR) peptide sequence, releasing p-nitroaniline (pNA) that can be detected colorimetrically at 405 nm. H-Gly-Arg-pNA hydrochloride is used as a fluorescent dye to measure thrombin activity[1].

References

[1] Hortin G L, et al. Macromolecular chromogenic substrates for measuring proteinase activity[J]. Clinical chemistry, 2001, 47(2): 215-222. PMID:11159769

GLY-ARG P-NITROANILIDE DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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GLY-ARG P-NITROANILIDE DIHYDROCHLORIDE Suppliers

Hangzhou Beiputai Biopharmaceutical Co., Ltd
Tel
0571-85350119 15888826472
Email
bptsales@163.com
Country
China
ProdList
3834
Advantage
58
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9125
Advantage
58
Nanjing Leon Biological Technology Co., Ltd.
Tel
17705183659
Fax
84523390
Email
sales@njleonbiotech.com
Country
China
ProdList
5501
Advantage
55
Nanjing Peptide Biotech Ltd.
Tel
025-58361106-805 15951641583
Fax
025-58361106-806
Email
zhao.xu@njpeptide.com
Country
China
ProdList
9979
Advantage
55
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
Shenzhen GeneSeqTools Bioscience & Technology Co. Ltd.
Tel
0755-23251735 13302967066
Email
sales@geneseqtools.com
Country
China
ProdList
1420
Advantage
58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
Tel
meitaochem@126.com
Email
meitaochem@126.com
Country
China
ProdList
19103
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58

125455-61-0, GLY-ARG P-NITROANILIDE DIHYDROCHLORIDERelated Search:


  • H-GLY-ARG-PNA 2HCL
  • GLY-ARG P-NITROANILIDE DIHYDROCHLORIDE
  • H-Gly-Arg-Pna dihydrochloride
  • Gly-Arg-4-NA
  • GLY-ARG-4-NA;GR-PNAGR; P-NITROANILIDE
  • GR-pNA GR
  • Gly-Arg-p-nitroanilide dihydrochloride unokinase and plasmin substrate
  • 125455-61-0
  • C14H21N7O42HCl
  • C14H21N7O42ClH
  • Coagulation Proteins and Reagents
  • Proteins and Derivatives
  • Plasma & Blood Proteins
  • BioChemical
  • Biochemicals and Reagents
  • Coagulation Proteins and ReagentsEnzyme Substrates
  • Plasma&Blood Proteins
  • PlasminEnzyme Substrates
  • Protease Substrates
  • Proteins and Derivatives
  • Substrates by Enzyme
  • Urokinase
  • UrokinaseEnzyme Substrates