GLY-ARG P-NITROANILIDE DIHYDROCHLORIDE

Product Name: GLY-ARG P-NITROANILIDE DIHYDROCHLORIDE
CAS No.: 125455-61-0
Chemical Name: GLY-ARG P-NITROANILIDE DIHYDROCHLORIDE
Synonyms: GR-pNA GR;Gly-Arg-4-NA;H-GLY-ARG-PNA 2HCL;H-Gly-Arg-Pna dihydrochloride;GLY-ARG-4-NA;GR-PNAGR; P-NITROANILIDE;GLY-ARG P-NITROANILIDE DIHYDROCHLORIDE;Gly-Arg-p-nitroanilide dihydrochloride unokinase and plasmin substrate
CBNumber: CB3682144
Molecular Formula: C14H23Cl2N7O4
Formula Weight: 424.28
MOL File: 125455-61-0.mol

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GLY-ARG P-NITROANILIDE DIHYDROCHLORIDE Property

storage temp.: −20°C
solubility: DMF: 20mg/mL; DMSO: 3mg/mL; PBS (pH 7.2): 3mg/mL
form: A solid
InChIKey: UMNMBKCWESYUMR-LCJJWKFENA-N
SMILES: C1(C=CC([N+]([O-])=O)=CC=1)NC(=O)[C@@H](NC(=O)CN)CCCNC(=N)N.Cl.Cl |&1:12,r|

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 27705
Product name: H-Gly-Arg-pNA (hydrochloride)
Packaging: 1mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 27705
Product name: H-Gly-Arg-pNA (hydrochloride)
Packaging: 25mg
Price: $618
Updated: 2024/03/01

Cayman Chemical

Product number: 27705
Product name: H-Gly-Arg-pNA (hydrochloride)
Packaging: 5mg
Price: $161
Updated: 2024/03/01

Cayman Chemical

Product number: 27705
Product name: H-Gly-Arg-pNA (hydrochloride)
Packaging: 10mg
Price: $283
Updated: 2024/03/01

American Custom Chemicals Corporation

Product number: AAA0004309
Product name: GLY-ARG-P-NITROANILIDE DIHYDROCHLORIDE
Purity: 95.00%
Packaging: 25MG
Price: $719.52
Updated: 2021/12/16

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GLY-ARG P-NITROANILIDE DIHYDROCHLORIDE Chemical Properties,Usage,Production

Description

H-Gly-Arg-pNA is a colorimetric substrate for thrombin. Thrombin preferentially binds to and cleaves the Gly-Arg (GR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of thrombin activity.

Uses

H-Gly-Arg-pNA hydrochloride (GR-pNA hydrochloride) is a colorimetric substrate for thrombin. H-Gly-Arg-pNA is preferentially bound by thrombin and cleaves the Gly-Arg (GR) peptide sequence, releasing p-nitroaniline (pNA) that can be detected colorimetrically at 405 nm. H-Gly-Arg-pNA hydrochloride is used as a fluorescent dye to measure thrombin activity[1].

References

[1] Hortin G L, et al. Macromolecular chromogenic substrates for measuring proteinase activity[J]. Clinical chemistry, 2001, 47(2): 215-222. PMID:11159769

GLY-ARG P-NITROANILIDE DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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GLY-ARG P-NITROANILIDE DIHYDROCHLORIDE Suppliers

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125455-61-0, GLY-ARG P-NITROANILIDE DIHYDROCHLORIDERelated Search:

Chymotrypsin Substrate II, Fluorogenic SAR-PRO-ARG P-NITROANILIDE DIHYDROCHLORIDE H-D-PRO-PHE-ARG-PNA 2 HCL GLY-ARG P-NITROANILIDE DIHYDROCHLORIDE Z-LYS-ARG-PNA 2 HCL CATHEPSIN B SUBSTRATE I, COLORIMETRIC Z-D-ARG-GLY-ARG-PNA 2 HCL D-ILE-PRO-ARG P-NITROANILIDE DIHYDROCHLORIDE

H-GLY-ARG-PNA 2HCL

GLY-ARG P-NITROANILIDE DIHYDROCHLORIDE

H-Gly-Arg-Pna dihydrochloride

Gly-Arg-4-NA

GLY-ARG-4-NA;GR-PNAGR; P-NITROANILIDE

GR-pNA GR

Gly-Arg-p-nitroanilide dihydrochloride unokinase and plasmin substrate

125455-61-0

C14H21N7O42HCl

C14H21N7O42ClH

Coagulation Proteins and Reagents

Proteins and Derivatives

Plasma & Blood Proteins

BioChemical

Biochemicals and Reagents

Coagulation Proteins and ReagentsEnzyme Substrates

Plasma&Blood Proteins

PlasminEnzyme Substrates

Protease Substrates

Proteins and Derivatives

Substrates by Enzyme

Urokinase

UrokinaseEnzyme Substrates