PENTAFLUOROBENZENESULFONYL CHLORIDE Property

Boiling point:

210-211 °C(lit.)

Density 

1.796 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.479(lit.)

Flash point:

195 °F

storage temp. 

Sealed in dry,Room Temperature

form 

clear liquid

color 

Colorless to Almost colorless

Specific Gravity

1.797

Water Solubility 

Soluble in water (reacts slowly).

Sensitive 

Moisture Sensitive

BRN 

2142325

CAS DataBase Reference

832-53-1(CAS DataBase Reference)

Safety

Hazard Codes 

C

Risk Statements 

34-37

Safety Statements 

26-36/37/39-45-24/25

RIDADR 

UN 3265 8/PG 2

WGK Germany 

3

F 

21

Hazard Note 

Corrosive

HazardClass 

8

PackingGroup 

II

HS Code 

29049090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

PENTAFLUOROBENZENESULFONYL CHLORIDE Chemical Properties,Usage,Production

Chemical Properties

clear colourless to light yellow liquid

Uses

Pentafluorobenzenesulfonyl chloride is used as derivatizing reagent for simultaneous determination of fluoxetine and p-trifluoromethylphenol, an O-dealkylated metabolite of fluoxetine in human liver microsomes. It is also used for electrophore labeling of small tyrosyl peptides for their analysis by gas chromatography with electron-capture detection. It is also employed as derivatizing reagent for amphetamine in determination of amphetamine in human plasma samples using gas chromatography with electron-capture detection.

General Description

Pentafluorobenzenesulfonyl chloride reacts with benzene and thiophene derivatives in the presence of a ruthenium (II) catalyst to form corresponding perfluorophenylated compounds.

Biochem/physiol Actions

Pentafluorobenzenesulfonyl chloride is derivatizing reagent for amphetamine in determination of amphetamine in human plasma samples using gas chromatography with electron-capture detectio.